Project name: 5vh3:L
Status: done
submitted: 2019-03-20 20:37:04, status changed: 2019-03-20 20:48:16
Settings
|
Chain sequence(s)
|
L: DILLTQSSPAILSVSPGERVSFSCRASQFVGSSSIHWYQQRTNGSPRLLIKYASESMSGIPSRFSGSGSGTDFTLSINTVESEDIADYYCQQSHSWPFTFGSGTNLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.702
-
Maximal score value
-
2.05
-
Average score
-
-0.7293
-
Total score value
-
-156.0671
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.1951 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
L |
L |
0.8943 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.4385 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.3994 |
|
| 8 |
P |
L |
0.0919 |
|
| 9 |
A |
L |
0.2351 |
|
| 10 |
I |
L |
0.7814 |
|
| 11 |
L |
L |
0.4312 |
|
| 12 |
S |
L |
-0.0603 |
|
| 13 |
V |
L |
0.0000 |
|
| 14 |
S |
L |
-1.3182 |
|
| 15 |
P |
L |
-1.5393 |
|
| 16 |
G |
L |
-1.9550 |
|
| 17 |
E |
L |
-2.4395 |
|
| 18 |
R |
L |
-2.9429 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
S |
L |
-0.8437 |
|
| 21 |
F |
L |
0.0000 |
|
| 22 |
S |
L |
-0.9293 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.2015 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-0.6138 |
|
| 27 |
Q |
L |
-0.5713 |
|
| 28 |
F |
L |
0.8549 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
G |
L |
0.1263 |
|
| 31 |
S |
L |
0.0433 |
|
| 32 |
S |
L |
0.2348 |
|
| 33 |
I |
L |
0.0000 |
|
| 34 |
H |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.3287 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.7509 |
|
| 39 |
R |
L |
-2.3723 |
|
| 40 |
T |
L |
-1.6671 |
|
| 41 |
N |
L |
-1.8488 |
|
| 42 |
G |
L |
-1.7449 |
|
| 43 |
S |
L |
-1.3804 |
|
| 44 |
P |
L |
-1.4871 |
|
| 45 |
R |
L |
-1.6960 |
|
| 46 |
L |
L |
-0.5558 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
K |
L |
-0.6931 |
|
| 50 |
Y |
L |
0.1977 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-1.0782 |
|
| 53 |
E |
L |
-1.9064 |
|
| 54 |
S |
L |
-1.1243 |
|
| 55 |
M |
L |
-0.5376 |
|
| 56 |
S |
L |
-0.5056 |
|
| 57 |
G |
L |
-0.4455 |
|
| 58 |
I |
L |
-0.2585 |
|
| 59 |
P |
L |
-0.3102 |
|
| 60 |
S |
L |
-0.6305 |
|
| 61 |
R |
L |
-1.3115 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-1.0207 |
|
| 64 |
G |
L |
-0.7297 |
|
| 65 |
S |
L |
-0.7581 |
|
| 66 |
G |
L |
-0.9196 |
|
| 67 |
S |
L |
-0.3665 |
|
| 68 |
G |
L |
-0.3501 |
|
| 69 |
T |
L |
-1.0781 |
|
| 70 |
D |
L |
-2.1345 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.8528 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
S |
L |
-0.9800 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
N |
L |
-2.6487 |
|
| 77 |
T |
L |
-2.3946 |
|
| 78 |
V |
L |
0.0000 |
|
| 79 |
E |
L |
-2.6917 |
|
| 80 |
S |
L |
-1.8016 |
|
| 81 |
E |
L |
-2.4163 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
I |
L |
-0.7900 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
D |
L |
-0.8021 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.1973 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
S |
L |
0.5748 |
|
| 92 |
H |
L |
0.1700 |
|
| 93 |
S |
L |
0.3448 |
|
| 94 |
W |
L |
0.9114 |
|
| 95 |
P |
L |
0.5002 |
|
| 96 |
F |
L |
1.4113 |
|
| 97 |
T |
L |
1.2844 |
|
| 98 |
F |
L |
2.0500 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
S |
L |
0.2459 |
|
| 101 |
G |
L |
0.0336 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
N |
L |
-0.2469 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
E |
L |
0.0000 |
|
| 106 |
V |
L |
-0.3452 |
|
| 107 |
K |
L |
-0.7596 |
|
| 108 |
R |
L |
-0.7833 |
|
| 109 |
T |
L |
-0.1198 |
|
| 110 |
V |
L |
0.2382 |
|
| 111 |
A |
L |
-0.1318 |
|
| 112 |
A |
L |
-0.2729 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1122 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.2606 |
|
| 117 |
I |
L |
1.2805 |
|
| 118 |
F |
L |
1.4875 |
|
| 119 |
P |
L |
-0.1455 |
|
| 120 |
P |
L |
-0.7459 |
|
| 121 |
S |
L |
-1.7868 |
|
| 122 |
D |
L |
-3.2985 |
|
| 123 |
E |
L |
-3.4530 |
|
| 124 |
Q |
L |
-2.4795 |
|
| 125 |
L |
L |
-2.5335 |
|
| 126 |
K |
L |
-3.0615 |
|
| 127 |
S |
L |
-1.9520 |
|
| 128 |
G |
L |
-1.3242 |
|
| 129 |
T |
L |
-1.1616 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0475 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7427 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5125 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6000 |
|
| 138 |
N |
L |
-1.1606 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.1433 |
|
| 142 |
R |
L |
-1.5836 |
|
| 143 |
E |
L |
-2.5588 |
|
| 144 |
A |
L |
-1.8394 |
|
| 145 |
K |
L |
-1.9725 |
|
| 146 |
V |
L |
-1.0340 |
|
| 147 |
Q |
L |
-0.7242 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.7414 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.9690 |
|
| 152 |
N |
L |
-1.5863 |
|
| 153 |
A |
L |
-0.3805 |
|
| 154 |
L |
L |
0.4516 |
|
| 155 |
Q |
L |
-0.2469 |
|
| 156 |
S |
L |
-0.4817 |
|
| 157 |
G |
L |
-1.0048 |
|
| 158 |
N |
L |
-0.9670 |
|
| 159 |
S |
L |
-1.4428 |
|
| 160 |
Q |
L |
-2.2882 |
|
| 161 |
E |
L |
-2.2126 |
|
| 162 |
S |
L |
-1.0675 |
|
| 163 |
V |
L |
-0.0896 |
|
| 164 |
T |
L |
-0.9131 |
|
| 165 |
E |
L |
-2.0321 |
|
| 166 |
Q |
L |
-1.9174 |
|
| 167 |
D |
L |
-2.4016 |
|
| 168 |
S |
L |
-1.9386 |
|
| 169 |
K |
L |
-2.4425 |
|
| 170 |
D |
L |
-1.9841 |
|
| 171 |
S |
L |
-1.7927 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.6944 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.3628 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.6148 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.5133 |
|
| 181 |
L |
L |
-0.7208 |
|
| 182 |
S |
L |
-1.0857 |
|
| 183 |
K |
L |
-2.1251 |
|
| 184 |
A |
L |
-1.9316 |
|
| 185 |
D |
L |
-2.6052 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.6132 |
|
| 188 |
K |
L |
-3.7020 |
|
| 189 |
H |
L |
-3.0891 |
|
| 190 |
K |
L |
-3.2728 |
|
| 191 |
V |
L |
-1.3797 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-1.0173 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.1344 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.6177 |
|
| 200 |
G |
L |
-0.4903 |
|
| 201 |
L |
L |
-0.2640 |
|
| 202 |
S |
L |
-0.4500 |
|
| 203 |
S |
L |
-0.4315 |
|
| 204 |
P |
L |
-0.5530 |
|
| 205 |
V |
L |
-0.1634 |
|
| 206 |
T |
L |
-0.4769 |
|
| 207 |
K |
L |
-0.3285 |
|
| 208 |
S |
L |
-0.2588 |
|
| 209 |
F |
L |
-0.6657 |
|
| 210 |
N |
L |
-1.8332 |
|
| 211 |
R |
L |
-2.5073 |
|
| 212 |
G |
L |
-2.2073 |
|
| 213 |
E |
L |
-2.1756 |
|
| 214 |
C |
L |
-0.3706 |
|