Project name: 3eo9:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGYSSFTGHWMNWVRQAPGKGLEWVGMIHPSDSETRYNQKFKDRFTISVDKSKNTLYLQMNSLRAEDTAVYYCARGIYFYGTTYFDYWGQGTLVTVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKV
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.7819
• Maximal score value: 3.0725
• Average score: -0.5165
• Total score value: -110.532

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.3129
2	V	H	0.0000
3	Q	H	-1.4725
4	L	H	0.0000
5	V	H	0.8704
6	E	H	0.0000
7	S	H	-0.2939
8	G	H	-0.6935
9	G	H	-0.0862
10	G	H	0.5471
11	L	H	0.8199
12	V	H	-0.3436
13	Q	H	-1.5339
14	P	H	-1.6866
15	G	H	-1.4648
16	G	H	-1.0244
17	S	H	-1.1850
18	L	H	-0.8835
19	R	H	-1.9943
20	L	H	0.0000
21	S	H	-0.3148
22	C	H	0.0000
23	A	H	-0.1219
24	A	H	0.0000
25	S	H	-1.1971
26	G	H	-1.6091
27	Y	H	-0.9851
28	S	H	-0.6687
29	F	H	0.0000
30	T	H	-1.1513
31	G	H	-0.6681
32	H	H	-0.3447
33	W	H	-0.0982
34	M	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.2769
40	A	H	-0.9668
41	P	H	-0.9908
42	G	H	-1.5715
43	K	H	-2.0333
44	G	H	-0.8642
45	L	H	0.7285
46	E	H	0.0455
47	W	H	0.2338
48	V	H	0.0000
49	G	H	0.0000
50	M	H	0.0000
51	I	H	0.0000
52	H	H	-1.5620
53	P	H	0.0000
54	S	H	-1.7674
55	D	H	-2.5427
56	S	H	-2.0705
57	E	H	-2.1191
58	T	H	-1.6861
59	R	H	-2.4211
60	Y	H	-2.0605
61	N	H	-2.0876
62	Q	H	-3.2006
63	K	H	-3.1678
64	F	H	0.0000
65	K	H	-3.7819
66	D	H	-3.3180
67	R	H	-2.1063
68	F	H	0.0000
69	T	H	-1.0346
70	I	H	0.0000
71	S	H	-0.4396
72	V	H	-1.2254
73	D	H	-2.0860
74	K	H	-2.9547
75	S	H	-2.0734
76	K	H	-2.6574
77	N	H	-2.0367
78	T	H	-1.1307
79	L	H	0.0000
80	Y	H	-0.3267
81	L	H	0.0000
82	Q	H	-1.0584
83	M	H	0.0000
84	N	H	-1.4954
85	S	H	-1.3754
86	L	H	0.0000
87	R	H	-2.7266
88	A	H	-1.9185
89	E	H	-2.3358
90	D	H	0.0000
91	T	H	-0.6017
92	A	H	0.0000
93	V	H	0.6176
94	Y	H	0.0000
95	Y	H	0.5458
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.2667
99	G	H	0.0000
100	I	H	1.7334
101	Y	H	2.4237
102	F	H	3.0725
103	Y	H	2.4397
104	G	H	1.0416
105	T	H	1.1184
106	T	H	1.5697
107	Y	H	1.9026
108	F	H	1.0944
109	D	H	0.2215
110	Y	H	0.4493
111	W	H	0.3909
112	G	H	-0.0100
113	Q	H	-0.7185
114	G	H	0.0494
115	T	H	0.4108
116	L	H	1.1629
117	V	H	0.0000
118	T	H	-0.1047
119	V	H	0.0000
120	S	H	-0.6893
121	S	H	-0.6315
122	A	H	-0.6553
123	S	H	-0.8541
124	T	H	-1.2034
125	K	H	-2.0853
126	G	H	-1.9483
127	P	H	0.0000
128	S	H	-0.3000
129	V	H	0.0000
130	F	H	0.9555
131	P	H	0.5223
132	L	H	0.7433
133	A	H	0.2384
134	P	H	0.0617
135	S	H	-0.2338
136	S	H	-0.2874
142	G	H	-0.6616
143	T	H	-0.4901
144	A	H	-0.2877
145	A	H	0.0689
146	L	H	0.0000
147	G	H	0.0000
148	C	H	0.0000
149	L	H	0.6427
150	V	H	0.0000
151	K	H	-0.3346
152	D	H	-0.9594
153	Y	H	0.0000
154	F	H	0.0000
155	P	H	-1.2854
156	E	H	-1.6495
157	P	H	-1.5666
158	V	H	-1.2175
159	T	H	-0.9228
160	V	H	-0.3032
161	S	H	-0.4048
162	W	H	0.0000
163	N	H	-0.6987
164	S	H	-0.5937
165	G	H	-0.5659
166	A	H	-0.2429
167	L	H	-0.0265
168	T	H	-0.3037
169	S	H	-0.3752
170	G	H	-0.4759
171	V	H	0.0131
172	H	H	-0.4243
173	T	H	0.1386
174	F	H	0.9228
175	P	H	0.6769
176	A	H	1.0451
177	V	H	2.4695
178	L	H	1.9922
179	Q	H	0.6944
180	S	H	0.1135
181	S	H	-0.2218
182	G	H	0.2044
183	L	H	-0.1069
184	Y	H	0.0000
185	S	H	0.0000
186	L	H	0.0000
187	S	H	0.6526
188	S	H	0.0000
189	V	H	0.4750
190	V	H	0.0000
191	T	H	-0.2312
192	V	H	0.0000
193	P	H	-0.5787
194	S	H	-0.5663
195	S	H	-0.5841
196	S	H	-0.5217
197	L	H	-0.2297
198	G	H	-0.5955
199	T	H	-0.6553
200	Q	H	-1.0114
201	T	H	-0.6451
202	Y	H	0.0000
203	I	H	-0.7595
204	C	H	0.0000
205	N	H	-1.4922
206	V	H	0.0000
207	N	H	-2.5115
208	H	H	0.0000
209	K	H	-3.0863
210	P	H	-2.0544
211	S	H	-2.1425
212	N	H	-2.8349
213	T	H	-2.3820
214	K	H	-2.8205
215	V	H	-1.4827
216	D	H	-2.2497
217	K	H	-1.5243
218	K	H	-1.7271
219	V	H	-0.1859