Project name: 5ggq:H

Chain sequence(s)	H: VQLVESGGGVVQPGRSLRLDCKASGITFSNSGMHWVRQAPGKGLEWVAVIWYDGSKRYYADSVKGRFTISRDNSKNTLFLQMNSLRAEDTAVYYCATNDDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0468
• Maximal score value: 2.4147
• Average score: -0.6455
• Total score value: -134.2599

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	H	1.1895
3	Q	H	-0.5749
4	L	H	0.0000
5	V	H	-0.7870
6	E	H	0.0000
7	S	H	-0.9991
8	G	H	-1.0094
9	G	H	-0.4558
10	G	H	-0.3225
11	V	H	-0.1275
12	V	H	0.0000
13	Q	H	-2.0232
14	P	H	-2.3098
15	G	H	-2.2831
16	R	H	-2.8226
17	S	H	-1.9303
18	L	H	-1.5107
19	R	H	-2.1494
20	L	H	0.0000
21	D	H	-1.4815
22	C	H	0.0000
23	K	H	-2.5002
24	A	H	0.0000
25	S	H	-0.6264
26	G	H	-0.0135
27	I	H	0.1132
28	T	H	-0.3073
29	F	H	0.0000
30	S	H	-1.3634
31	N	H	-1.3366
32	S	H	-1.0941
33	G	H	-1.2324
34	M	H	0.0000
35	H	H	-0.3636
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.5004
40	A	H	-1.0794
41	P	H	-1.0375
42	G	H	-1.5726
43	K	H	-2.1152
44	G	H	-1.0144
45	L	H	0.4933
46	E	H	-0.4335
47	W	H	0.3085
48	V	H	0.0000
49	A	H	0.0000
50	V	H	0.0000
51	I	H	0.0000
52	W	H	-0.5580
53	Y	H	-0.7200
54	D	H	-1.8880
55	G	H	-1.2606
56	S	H	-1.1703
57	K	H	-1.2773
58	R	H	-0.6709
59	Y	H	0.1276
60	Y	H	-0.4846
61	A	H	-1.0542
62	D	H	-2.3676
63	S	H	-1.6456
64	V	H	0.0000
65	K	H	-2.4862
66	G	H	-1.7801
67	R	H	-1.5976
68	F	H	0.0000
69	T	H	-0.7902
70	I	H	0.0000
71	S	H	-0.7067
72	R	H	-1.1875
73	D	H	-1.8443
74	N	H	-2.1527
75	S	H	-1.6110
76	K	H	-2.7170
77	N	H	-2.3966
78	T	H	0.0000
79	L	H	0.0000
80	F	H	-0.8050
81	L	H	0.0000
82	Q	H	-1.1890
83	M	H	0.0000
84	N	H	-1.8823
85	S	H	-1.8052
86	L	H	0.0000
87	R	H	-2.9020
88	A	H	-1.8466
89	E	H	-2.3532
90	D	H	0.0000
91	T	H	-0.7291
92	A	H	0.0000
93	V	H	0.4683
94	Y	H	0.0000
95	Y	H	0.3960
96	C	H	0.0000
97	A	H	0.0000
98	T	H	0.0000
99	N	H	-2.4559
100	D	H	-3.0468
101	D	H	-2.6199
102	Y	H	-0.4871
103	W	H	-0.2316
104	G	H	-0.6751
105	Q	H	-0.9889
106	G	H	0.0000
107	T	H	0.0408
108	L	H	0.6917
109	V	H	0.0000
110	T	H	0.0000
111	V	H	0.0000
112	S	H	-0.7325
113	S	H	-0.8159
114	A	H	-0.4434
115	S	H	-0.6284
116	T	H	-1.0126
117	K	H	-1.4540
118	G	H	-1.5918
119	P	H	-0.7177
120	S	H	-0.2601
121	V	H	0.0000
122	F	H	0.4098
123	P	H	0.0724
124	L	H	0.6364
125	A	H	0.0806
126	P	H	-0.5414
127	S	H	-0.7210
128	S	H	-1.2429
129	K	H	-2.0681
130	S	H	-1.3258
131	T	H	-1.0553
132	S	H	-0.7473
133	G	H	-0.7994
134	G	H	-0.8687
135	T	H	-0.5688
136	A	H	0.0000
137	A	H	0.2109
138	L	H	0.6032
139	G	H	0.0000
140	C	H	0.0000
141	L	H	0.4575
142	V	H	0.0000
143	K	H	-0.3091
144	D	H	-0.4823
145	Y	H	0.0000
146	F	H	-0.3903
147	P	H	0.0000
148	E	H	-0.7177
149	P	H	-0.8348
150	V	H	0.0000
151	T	H	-0.6424
152	V	H	-0.4467
153	S	H	-0.4820
154	W	H	0.0000
155	N	H	-0.4239
156	S	H	-0.6267
157	G	H	-0.5838
158	A	H	-0.2389
159	L	H	0.0171
160	T	H	-0.3150
161	S	H	-0.3804
162	G	H	-0.4793
163	V	H	0.0034
164	H	H	-0.4641
165	T	H	0.1815
166	F	H	0.9457
167	P	H	0.6970
168	A	H	1.1700
169	V	H	2.4147
170	L	H	2.0273
171	Q	H	0.4253
172	S	H	-0.0741
173	S	H	-0.3266
174	G	H	0.1101
175	L	H	0.2031
176	Y	H	0.6559
177	S	H	0.0000
178	L	H	0.0000
179	S	H	0.6340
180	S	H	0.0000
181	V	H	0.5068
182	V	H	0.0000
183	T	H	-0.1725
184	V	H	0.0000
185	P	H	-0.6039
186	S	H	-0.8897
187	S	H	-0.8298
188	S	H	-0.5945
189	L	H	-0.8121
190	G	H	-0.9607
191	T	H	-0.6842
192	Q	H	-0.9141
193	T	H	-0.3307
194	Y	H	-0.2565
195	I	H	-0.5304
196	C	H	0.0000
197	N	H	-1.5929
198	V	H	0.0000
199	N	H	-1.8647
200	H	H	0.0000
201	K	H	-2.7189
202	P	H	-1.6051
203	S	H	-1.8342
204	N	H	-2.5716
205	T	H	-2.1272
206	K	H	-2.6373
207	V	H	-1.6956
208	D	H	-2.6959
209	K	H	-2.0538