Project name: 5wkz:H

Chain sequence(s)	H: QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANYAQKFQGRVTITADESTSTAYMELSSLRSEDTAVYYCARHMGYQLRETMDVWGKGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8534
• Maximal score value: 2.3991
• Average score: -0.5433
• Total score value: -120.0657

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5094
2	V	H	-1.1179
3	Q	H	-1.4984
4	L	H	0.0000
5	V	H	0.2378
6	Q	H	-0.3867
7	S	H	-0.6884
8	G	H	-0.5155
9	A	H	-0.3278
10	E	H	-0.4506
11	V	H	0.0757
12	K	H	-1.2152
13	K	H	-2.1464
14	P	H	-2.1359
15	G	H	-1.5131
16	S	H	-1.1897
17	S	H	-1.3385
18	V	H	0.0000
19	K	H	-1.9825
20	V	H	0.0000
21	S	H	-0.5840
22	C	H	0.0000
23	K	H	-1.0855
24	A	H	0.0000
25	S	H	-0.8914
26	G	H	-1.2280
27	G	H	-1.0262
28	T	H	-0.8441
29	F	H	0.0000
30	S	H	-0.2261
31	S	H	0.6985
32	Y	H	1.0798
33	A	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.0201
39	Q	H	-0.4165
40	A	H	-1.0052
41	P	H	-1.1757
42	G	H	-1.3245
43	Q	H	-1.5653
44	G	H	-0.6522
45	L	H	0.8751
46	E	H	0.2134
47	W	H	0.4250
48	M	H	0.0000
49	G	H	0.0000
50	G	H	0.0000
51	I	H	0.3969
52	I	H	0.0000
53	P	H	0.7425
54	I	H	1.9627
55	F	H	2.0863
56	G	H	0.7073
57	T	H	0.3038
58	A	H	-0.2434
59	N	H	-1.1094
60	Y	H	-1.0845
61	A	H	-1.4433
62	Q	H	-2.5781
63	K	H	-2.6360
64	F	H	0.0000
65	Q	H	-2.5010
66	G	H	-1.6346
67	R	H	-1.5740
68	V	H	0.0000
69	T	H	-0.9511
70	I	H	0.0000
71	T	H	-0.4600
72	A	H	-1.0006
73	D	H	-1.8297
74	E	H	-2.1996
75	S	H	-1.3683
76	T	H	-1.2171
77	S	H	-1.5209
78	T	H	0.0000
79	A	H	0.0000
80	Y	H	-0.6614
81	M	H	0.0000
82	E	H	-1.6224
83	L	H	0.0000
84	S	H	-1.1394
85	S	H	-1.1123
86	L	H	0.0000
87	R	H	-2.8308
88	S	H	-2.2590
89	E	H	-2.4965
90	D	H	0.0000
91	T	H	-0.9956
92	A	H	0.0000
93	V	H	0.0597
94	Y	H	0.0000
95	Y	H	0.0100
96	C	H	0.0000
97	A	H	0.0000
98	R	H	-0.0963
99	H	H	0.0000
100	M	H	0.3980
101	G	H	0.2954
102	Y	H	1.1530
103	Q	H	-0.2015
104	L	H	-0.6825
105	R	H	-1.8062
106	E	H	-1.1882
107	T	H	-0.7795
108	M	H	-0.5347
109	D	H	-1.2455
110	V	H	-0.5190
111	W	H	-0.1676
112	G	H	0.0000
113	K	H	-1.4386
114	G	H	-0.6545
115	T	H	0.0000
116	T	H	-0.2292
117	V	H	0.0000
118	T	H	-0.6480
119	V	H	0.0000
120	S	H	-1.1827
121	S	H	-1.1012
122	A	H	-0.6100
123	S	H	-0.6773
124	T	H	-0.7424
125	K	H	-1.1910
126	G	H	-1.4336
127	P	H	-0.5975
128	S	H	-0.0741
129	V	H	0.0000
130	F	H	0.9774
131	P	H	0.0273
132	L	H	0.5451
133	A	H	-0.5004
134	P	H	0.0000
135	S	H	-1.0229
136	S	H	-1.1889
137	K	H	-1.9149
138	S	H	-1.0149
139	T	H	-1.0334
140	S	H	-0.9885
141	G	H	-0.8431
142	G	H	-0.8959
143	T	H	-0.6148
144	A	H	0.0000
145	A	H	-0.2042
146	L	H	0.0000
147	G	H	0.0000
148	C	H	0.0000
149	L	H	0.7953
150	V	H	0.0000
151	K	H	-0.2087
152	D	H	-0.3239
153	Y	H	0.0000
154	F	H	0.0000
155	P	H	0.0000
156	E	H	-0.8819
157	P	H	-1.1180
158	V	H	-0.9064
159	T	H	-0.6773
160	V	H	-0.3488
161	S	H	-0.4852
162	W	H	0.0000
163	N	H	-0.9347
164	S	H	-0.7082
165	G	H	-0.5757
166	A	H	-0.2787
167	L	H	-0.0497
168	T	H	-0.3373
169	S	H	-0.3957
170	G	H	-0.5027
171	V	H	-0.1166
172	H	H	-0.6274
173	T	H	0.0151
174	F	H	0.6933
175	P	H	0.4105
176	A	H	1.1035
177	V	H	2.3991
178	L	H	2.0675
179	Q	H	0.5695
180	S	H	0.0027
181	S	H	-0.2445
182	G	H	-0.0076
183	L	H	0.2126
184	Y	H	0.6944
185	S	H	0.6437
186	L	H	0.0000
187	S	H	0.5833
188	S	H	0.0000
189	V	H	0.3197
190	V	H	0.0000
191	T	H	-0.2623
192	V	H	0.0000
193	P	H	-0.6348
194	S	H	-0.5711
195	S	H	-0.5702
196	S	H	0.0000
197	L	H	-0.8237
198	G	H	-1.0372
199	T	H	-0.8423
200	Q	H	-1.5012
201	T	H	-1.3122
202	Y	H	0.0000
203	I	H	-1.4741
204	C	H	0.0000
205	N	H	0.0000
206	V	H	0.0000
207	N	H	-2.0741
208	H	H	0.0000
209	K	H	-2.8534
210	P	H	-1.6087
211	S	H	-1.9317
212	N	H	-2.6113
213	T	H	-2.1217
214	K	H	-2.7229
215	V	H	-1.5505
216	D	H	-2.6543
217	K	H	-2.0696
218	R	H	-2.6724
219	V	H	0.0000
220	E	H	-2.5105
221	P	H	-1.1546