Project name: b91f43caca79492

Chain sequence(s)	A: VNPTVFFDIAVDGEPLGRVSSFELFADKVPKKTAENFRALSTGEKKGFGYKGSCCFHRIIPGFMCQGGDFTRRHNGTGGKSIYGEKKFEEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKKVKEEGMNIVEAMERFGSRNGKTSKKKITIADCGQLEE; B: VVHGVATVAEKTK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4162
• Maximal score value: 2.3916
• Average score: -0.9306
• Total score value: -164.7133

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	A	1.3262
3	N	A	-0.0313
4	P	A	-0.4164
5	T	A	-0.7655
6	V	A	0.0000
7	F	A	0.0000
8	F	A	0.0000
9	D	A	-1.3346
10	I	A	0.0000
11	A	A	0.0000
12	V	A	0.0000
13	D	A	-3.4162
14	G	A	-2.5912
15	E	A	-2.7725
16	P	A	-1.5290
17	L	A	-0.6054
18	G	A	-0.9584
19	R	A	-1.8423
20	V	A	0.0000
21	S	A	0.0000
22	F	A	0.0000
23	E	A	-1.3052
24	L	A	0.0000
25	F	A	-0.9066
26	A	A	-1.3613
27	D	A	-2.0782
28	K	A	-1.6341
29	V	A	0.0000
30	P	A	-1.6509
31	K	A	-1.7889
32	T	A	0.0000
33	A	A	0.0000
34	E	A	-1.1344
35	N	A	0.0000
36	F	A	0.0000
37	R	A	-1.0159
38	A	A	0.0000
39	L	A	0.0000
40	S	A	0.0000
41	T	A	-1.4979
42	G	A	-1.9761
43	E	A	-2.7368
44	K	A	-2.4928
45	G	A	-1.5629
46	F	A	-0.9135
47	G	A	-1.1578
48	Y	A	0.0000
49	K	A	-2.0546
50	G	A	-1.3863
51	S	A	0.0000
52	C	A	-0.9954
53	F	A	0.0000
54	H	A	-1.4738
55	R	A	-1.3227
56	I	A	0.0000
57	I	A	0.0000
58	P	A	-1.4613
59	G	A	-1.3105
60	F	A	0.0000
61	M	A	0.0000
62	C	A	0.0000
63	Q	A	0.0000
64	G	A	0.0000
65	G	A	0.0000
66	D	A	0.0000
67	F	A	-1.2594
68	T	A	-1.5014
69	R	A	-2.7413
70	H	A	-2.5230
71	N	A	-2.4131
72	G	A	-1.2446
73	T	A	-0.7877
74	G	A	-1.2498
75	G	A	-1.1796
76	K	A	-1.5706
77	S	A	0.0000
78	I	A	-0.8185
79	Y	A	-0.6870
80	G	A	-1.4287
81	E	A	-2.6165
82	K	A	-2.5552
83	F	A	0.0000
84	E	A	-3.1700
85	D	A	-2.3429
86	E	A	-1.4922
87	N	A	-0.3992
88	F	A	0.2755
89	I	A	1.4227
90	L	A	0.4806
91	K	A	-1.1964
92	H	A	0.0000
93	T	A	-1.2388
94	G	A	-1.3693
95	P	A	-0.9213
96	G	A	0.0000
97	I	A	0.0000
98	L	A	0.0000
99	S	A	0.0000
100	M	A	0.0000
101	A	A	0.0000
102	N	A	0.0000
103	A	A	-0.4498
104	G	A	-0.8810
105	P	A	-1.7326
106	N	A	-2.6938
107	T	A	-1.7840
108	N	A	0.0000
109	G	A	0.0000
110	S	A	0.0000
111	Q	A	0.0000
112	F	A	0.0000
113	F	A	0.0000
114	I	A	0.0000
115	C	A	0.0000
116	T	A	-0.7854
117	A	A	-1.1644
118	K	A	-2.1481
119	T	A	0.0000
120	E	A	-1.6217
121	W	A	-1.4325
122	L	A	0.0000
123	D	A	-1.4051
124	G	A	-1.3816
125	K	A	-2.3575
126	H	A	0.0000
127	V	A	0.0000
128	V	A	0.0000
129	F	A	0.0000
130	G	A	0.0000
131	K	A	-1.3842
132	V	A	-1.6193
133	K	A	-2.8075
134	E	A	-3.0770
135	G	A	-1.9892
136	M	A	-1.6114
137	N	A	-1.8221
138	I	A	-1.0492
139	V	A	0.0000
140	E	A	-1.6609
141	A	A	-1.1090
142	M	A	0.0000
143	E	A	-1.5342
144	R	A	-2.1408
145	F	A	-1.4955
146	G	A	-2.1170
147	S	A	-2.2964
148	R	A	-2.8831
149	N	A	-2.7223
150	G	A	0.0000
151	K	A	-2.8250
152	T	A	-2.2555
153	S	A	-1.6795
154	K	A	-2.5626
155	K	A	-3.1772
156	I	A	0.0000
157	T	A	-1.6098
158	I	A	0.0000
159	A	A	-1.4342
160	D	A	-1.6944
161	C	A	-1.2789
162	G	A	-1.1607
163	Q	A	-0.8937
164	L	A	-0.7031
165	E	A	-1.7107
48	V	B	2.3916
49	V	B	2.1729
50	H	B	0.2415
51	G	B	0.0011
52	V	B	0.9249
53	A	B	0.3000
54	T	B	-0.0177
55	V	B	0.0000
56	A	B	-1.0609
57	E	B	-2.4404
58	K	B	-2.3979
59	T	B	-1.7809
60	K	B	-2.2234