Project name: 5cma:A
Status: done
submitted: 2019-03-20 20:24:49, status changed: 2019-03-20 20:33:39
Settings
|
Chain sequence(s)
|
A: DIVMTQSPATLSVTPGDRVSLSCRASQSISDYLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSGSDFTLSINSVEPEDVGVYYCQNGHSFPLTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7051
-
Maximal score value
-
1.9635
-
Average score
-
-0.8693
-
Total score value
-
-185.17
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.3281 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
V |
A |
0.1092 |
|
| 4 |
M |
A |
0.0000 |
|
| 5 |
T |
A |
-0.4837 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
-0.5401 |
|
| 8 |
P |
A |
-0.2561 |
|
| 9 |
A |
A |
-0.1701 |
|
| 10 |
T |
A |
-0.2818 |
|
| 11 |
L |
A |
-0.0381 |
|
| 12 |
S |
A |
-0.4016 |
|
| 13 |
V |
A |
0.0000 |
|
| 14 |
T |
A |
-1.7374 |
|
| 15 |
P |
A |
-2.1001 |
|
| 16 |
G |
A |
-2.2724 |
|
| 17 |
D |
A |
-3.3020 |
|
| 18 |
R |
A |
-3.2445 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.7849 |
|
| 21 |
L |
A |
0.0000 |
|
| 22 |
S |
A |
-1.1577 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.7823 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-1.5681 |
|
| 27 |
Q |
A |
-1.9825 |
|
| 28 |
S |
A |
-1.5871 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
S |
A |
-1.1513 |
|
| 31 |
D |
A |
-1.3808 |
|
| 32 |
Y |
A |
-0.4279 |
|
| 33 |
L |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.2437 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.6052 |
|
| 39 |
K |
A |
-2.1068 |
|
| 40 |
S |
A |
-1.8331 |
|
| 41 |
H |
A |
-2.3339 |
|
| 42 |
E |
A |
-2.9255 |
|
| 43 |
S |
A |
-1.9190 |
|
| 44 |
P |
A |
-1.6513 |
|
| 45 |
R |
A |
-1.9132 |
|
| 46 |
L |
A |
-0.6262 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.9661 |
|
| 50 |
Y |
A |
-0.6156 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1450 |
|
| 53 |
Q |
A |
-1.6094 |
|
| 54 |
S |
A |
-0.8639 |
|
| 55 |
I |
A |
-0.2765 |
|
| 56 |
S |
A |
-0.3376 |
|
| 57 |
G |
A |
-0.4065 |
|
| 58 |
I |
A |
-0.2154 |
|
| 59 |
P |
A |
-0.3446 |
|
| 60 |
S |
A |
-0.5367 |
|
| 61 |
R |
A |
-1.0536 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.6804 |
|
| 64 |
G |
A |
-0.6899 |
|
| 65 |
S |
A |
-0.9755 |
|
| 66 |
G |
A |
-1.4817 |
|
| 67 |
S |
A |
-1.2540 |
|
| 68 |
G |
A |
-1.5552 |
|
| 69 |
S |
A |
-2.2298 |
|
| 70 |
D |
A |
-2.9853 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9982 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.8856 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.2421 |
|
| 77 |
S |
A |
-2.2740 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.4388 |
|
| 80 |
P |
A |
-2.4915 |
|
| 81 |
E |
A |
-2.7900 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
V |
A |
0.0000 |
|
| 84 |
G |
A |
0.0000 |
|
| 85 |
V |
A |
-0.1855 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.4439 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.0000 |
|
| 90 |
N |
A |
0.0000 |
|
| 91 |
G |
A |
0.1273 |
|
| 92 |
H |
A |
-0.4068 |
|
| 93 |
S |
A |
0.3375 |
|
| 94 |
F |
A |
1.6064 |
|
| 95 |
P |
A |
0.8555 |
|
| 96 |
L |
A |
1.4785 |
|
| 97 |
T |
A |
1.2046 |
|
| 98 |
F |
A |
1.9635 |
|
| 99 |
G |
A |
0.0000 |
|
| 100 |
A |
A |
0.5083 |
|
| 101 |
G |
A |
0.0000 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.7453 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-0.8763 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.2576 |
|
| 108 |
R |
A |
-0.9568 |
|
| 109 |
T |
A |
-0.1787 |
|
| 110 |
V |
A |
0.1370 |
|
| 111 |
A |
A |
-0.2987 |
|
| 112 |
A |
A |
-0.3314 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.2077 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.1766 |
|
| 117 |
I |
A |
1.1858 |
|
| 118 |
F |
A |
1.3902 |
|
| 119 |
P |
A |
0.0172 |
|
| 120 |
P |
A |
-0.7819 |
|
| 121 |
S |
A |
-1.8733 |
|
| 122 |
D |
A |
-3.3010 |
|
| 123 |
E |
A |
-3.4176 |
|
| 124 |
Q |
A |
-2.5145 |
|
| 125 |
L |
A |
-2.6237 |
|
| 126 |
K |
A |
-3.0616 |
|
| 127 |
S |
A |
-1.9313 |
|
| 128 |
G |
A |
-1.6936 |
|
| 129 |
T |
A |
-1.3994 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0232 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.6684 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.6342 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.7952 |
|
| 138 |
N |
A |
-1.5055 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
0.0000 |
|
| 141 |
P |
A |
-1.8480 |
|
| 142 |
R |
A |
-3.1620 |
|
| 143 |
E |
A |
-3.2779 |
|
| 144 |
A |
A |
-2.3761 |
|
| 145 |
K |
A |
-2.4347 |
|
| 146 |
V |
A |
-1.0633 |
|
| 147 |
Q |
A |
-0.5387 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.4979 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-2.0744 |
|
| 152 |
N |
A |
-1.3949 |
|
| 153 |
A |
A |
-0.2986 |
|
| 154 |
L |
A |
0.7490 |
|
| 155 |
Q |
A |
-0.2251 |
|
| 156 |
S |
A |
-0.7351 |
|
| 157 |
G |
A |
-1.3810 |
|
| 158 |
N |
A |
-1.7102 |
|
| 159 |
S |
A |
-1.7716 |
|
| 160 |
Q |
A |
-2.4806 |
|
| 161 |
E |
A |
-2.3580 |
|
| 162 |
S |
A |
-1.3169 |
|
| 163 |
V |
A |
-0.6879 |
|
| 164 |
T |
A |
-1.2453 |
|
| 165 |
E |
A |
-2.3783 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.5002 |
|
| 168 |
S |
A |
-2.6169 |
|
| 169 |
K |
A |
-2.8690 |
|
| 170 |
D |
A |
-2.1895 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-1.1120 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4699 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.7009 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.6856 |
|
| 181 |
L |
A |
-0.8145 |
|
| 182 |
S |
A |
-1.1314 |
|
| 183 |
K |
A |
-2.2421 |
|
| 184 |
A |
A |
-1.9408 |
|
| 185 |
D |
A |
-2.6069 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.5973 |
|
| 188 |
K |
A |
-3.7051 |
|
| 189 |
H |
A |
-3.0901 |
|
| 190 |
K |
A |
-3.1347 |
|
| 191 |
V |
A |
-1.2661 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.9323 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.2299 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.8116 |
|
| 200 |
G |
A |
-0.5262 |
|
| 201 |
L |
A |
-0.2887 |
|
| 202 |
S |
A |
-0.4767 |
|
| 203 |
S |
A |
-0.4378 |
|
| 204 |
P |
A |
-0.5764 |
|
| 205 |
V |
A |
-0.0673 |
|
| 206 |
T |
A |
-0.4001 |
|
| 207 |
K |
A |
-0.3678 |
|
| 208 |
S |
A |
-0.2067 |
|
| 209 |
F |
A |
-0.6665 |
|
| 210 |
N |
A |
-1.8447 |
|
| 211 |
R |
A |
-2.5201 |
|
| 212 |
G |
A |
-2.1789 |
|
| 213 |
E |
A |
-2.5023 |
|