Project name: ba3e7588dc2da36

Chain sequence(s)	A: TEASQPIVEEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIIEAIPLALQGRDIIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISSEQFEEALGSSIGVQSSAVIVGGIDSMMSQSSLALAKKPHIIIATPGRLIIDHLENTKGFNLRALLKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQQKLQRAALKNPVKCAVSS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5279
• Maximal score value: 0.8514
• Average score: -0.9388
• Total score value: -206.5398

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
11	T	A	-1.3242
12	E	A	-2.2929
13	A	A	-1.4385
14	S	A	-1.0825
15	Q	A	-1.0459
16	P	A	0.0000
17	I	A	0.8514
18	V	A	0.5622
19	E	A	-1.8234
20	E	A	-1.8826
21	E	A	-1.9858
22	E	A	-2.7427
23	T	A	-2.2904
24	K	A	-2.6871
25	T	A	-2.2337
26	F	A	0.0000
27	K	A	-3.3496
28	D	A	-2.9188
29	L	A	0.0000
30	G	A	-1.8867
31	V	A	0.0000
32	T	A	-1.7316
33	D	A	-2.3258
34	V	A	-0.7094
35	L	A	0.0000
36	C	A	-2.2518
37	E	A	-3.1064
38	A	A	-1.8136
39	C	A	0.0000
40	D	A	-3.0905
41	Q	A	-2.4287
42	L	A	-1.1628
43	G	A	-1.5272
44	W	A	-1.2271
45	T	A	-1.5030
46	K	A	-1.8715
47	P	A	0.0000
48	T	A	-0.6685
49	K	A	-0.7167
50	I	A	0.0000
51	Q	A	0.0000
52	I	A	0.0000
53	E	A	0.0000
54	A	A	0.0000
55	I	A	0.0000
56	P	A	-0.5926
57	L	A	-0.4112
58	A	A	0.0000
59	L	A	-0.3836
60	Q	A	-1.2794
61	G	A	-1.1294
62	R	A	-1.7943
63	D	A	0.0000
64	I	A	0.0000
65	I	A	0.0000
66	G	A	0.0000
67	L	A	-0.2468
68	A	A	0.0000
69	E	A	-2.0576
70	T	A	-1.2882
71	G	A	-1.0764
72	S	A	0.0000
73	G	A	-0.6288
74	K	A	0.0000
75	T	A	0.0000
76	G	A	0.0000
77	A	A	0.0000
78	F	A	0.0000
79	A	A	0.0000
80	L	A	0.0000
81	P	A	0.0000
82	I	A	0.0000
83	L	A	0.0000
84	N	A	0.0000
85	A	A	-0.5960
86	L	A	0.0000
87	L	A	-0.3426
88	E	A	-1.6772
89	T	A	-1.0934
90	P	A	-0.9619
91	Q	A	-1.3701
92	R	A	-2.1994
93	L	A	-1.7044
94	F	A	0.0000
95	A	A	0.0000
96	L	A	0.0000
97	V	A	0.0000
98	L	A	0.0000
99	T	A	0.0000
100	P	A	0.0000
101	T	A	-1.2021
102	R	A	-1.8004
103	E	A	-2.2449
104	L	A	0.0000
105	A	A	0.0000
106	F	A	-1.0336
107	Q	A	-1.8124
108	I	A	0.0000
109	S	A	-1.6166
110	E	A	-2.5142
111	Q	A	-1.5913
112	F	A	0.0000
113	E	A	-2.2616
114	A	A	-1.3261
115	L	A	0.0000
116	G	A	0.0000
117	S	A	-1.1080
118	S	A	-0.3580
119	I	A	0.1665
120	G	A	-0.6039
121	V	A	0.0000
122	Q	A	-1.9139
123	S	A	-1.3101
124	A	A	0.0000
125	V	A	0.3287
126	I	A	0.0000
127	V	A	0.0000
128	G	A	-0.8212
129	G	A	-0.8695
130	I	A	-0.5470
131	D	A	-1.4706
132	S	A	-0.5379
133	M	A	0.6870
134	S	A	0.2368
135	Q	A	0.0000
136	S	A	-0.1162
137	L	A	0.6955
138	A	A	-0.2983
139	L	A	0.0000
140	A	A	-1.1486
141	K	A	-2.2914
142	K	A	-2.5186
143	P	A	0.0000
144	H	A	-1.5368
145	I	A	0.0000
146	I	A	0.0000
147	I	A	0.0000
148	A	A	0.0000
149	T	A	-0.5162
150	P	A	0.0000
151	G	A	-0.5191
152	R	A	-1.0075
153	L	A	0.0000
154	I	A	-1.1751
155	D	A	-1.8676
156	H	A	0.0000
157	L	A	-1.7018
158	E	A	-3.0072
159	N	A	-2.8402
160	T	A	-1.9915
161	K	A	-2.6113
162	G	A	-1.7866
163	F	A	0.0000
164	N	A	-1.6143
165	L	A	0.0000
166	R	A	-2.1911
167	A	A	-1.4473
168	L	A	0.0000
169	K	A	-2.1494
170	Y	A	0.0000
171	L	A	0.0000
172	V	A	0.0000
173	M	A	0.0000
174	D	A	0.0000
175	E	A	-1.4842
176	A	A	0.0000
177	D	A	-1.7682
178	R	A	-2.6873
179	I	A	0.0000
180	L	A	0.0000
181	N	A	-2.6082
182	M	A	-1.6806
183	D	A	-2.3809
184	F	A	-1.6310
185	E	A	-1.7124
186	T	A	-1.3200
187	E	A	-1.3677
188	V	A	0.0000
189	D	A	-1.8397
190	K	A	-1.6785
191	I	A	0.0000
192	L	A	0.0000
193	K	A	-2.0042
194	V	A	-0.9712
195	I	A	0.0000
196	P	A	-2.4376
197	R	A	-3.5279
198	D	A	-3.3236
199	R	A	-2.5786
200	K	A	-2.1919
201	T	A	0.0000
202	F	A	0.0000
203	L	A	0.0000
204	F	A	0.0000
205	S	A	0.0000
206	A	A	-0.8801
207	T	A	-0.2784
208	M	A	-0.4663
209	T	A	-1.3869
210	K	A	-2.5526
211	K	A	-2.4343
212	V	A	0.0000
213	Q	A	-2.4915
214	K	A	-2.6607
215	L	A	0.0000
216	Q	A	-2.1810
217	R	A	-2.8482
218	A	A	-1.5910
219	A	A	0.0000
220	L	A	0.0000
221	K	A	-3.3407
222	N	A	-2.5974
223	P	A	-2.1177
224	V	A	0.0000
225	K	A	-1.4357
226	C	A	0.0000
227	A	A	-0.7524
228	V	A	-0.4075
229	S	A	-0.4772
230	S	A	-0.7425