Project name: 5id1:A
Status: done
submitted: 2019-03-20 20:31:10, status changed: 2019-03-20 20:43:30
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.783
-
Maximal score value
-
1.7281
-
Average score
-
-0.8352
-
Total score value
-
-177.0718
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.4034 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7746 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.2690 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
0.0762 |
|
| 8 |
P |
A |
0.7332 |
|
| 9 |
V |
A |
1.7281 |
|
| 10 |
I |
A |
1.0714 |
|
| 11 |
L |
A |
0.3723 |
|
| 12 |
S |
A |
-0.5084 |
|
| 13 |
V |
A |
-1.1843 |
|
| 14 |
S |
A |
-1.7781 |
|
| 15 |
P |
A |
-1.8842 |
|
| 16 |
G |
A |
-2.1399 |
|
| 17 |
E |
A |
-2.8754 |
|
| 18 |
R |
A |
-3.3655 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.8409 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.8526 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.5628 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-1.0658 |
|
| 27 |
Q |
A |
-1.6605 |
|
| 28 |
S |
A |
-1.5802 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.0563 |
|
| 31 |
T |
A |
-0.7191 |
|
| 32 |
N |
A |
-0.9145 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.0243 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.5951 |
|
| 39 |
R |
A |
-2.2625 |
|
| 40 |
T |
A |
-1.9333 |
|
| 41 |
N |
A |
-1.8187 |
|
| 42 |
G |
A |
-1.5915 |
|
| 43 |
S |
A |
-1.0834 |
|
| 44 |
P |
A |
-1.0117 |
|
| 45 |
R |
A |
-0.7730 |
|
| 46 |
L |
A |
-0.0319 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.6655 |
|
| 50 |
Y |
A |
-0.0990 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1258 |
|
| 53 |
E |
A |
-1.8644 |
|
| 54 |
S |
A |
-1.0800 |
|
| 55 |
I |
A |
-0.4780 |
|
| 56 |
S |
A |
-0.2482 |
|
| 57 |
G |
A |
-0.4280 |
|
| 58 |
I |
A |
-0.1427 |
|
| 59 |
P |
A |
-0.2976 |
|
| 60 |
S |
A |
-0.6167 |
|
| 61 |
R |
A |
-1.2453 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.9967 |
|
| 64 |
G |
A |
0.0000 |
|
| 65 |
S |
A |
-0.8028 |
|
| 66 |
G |
A |
-1.1348 |
|
| 67 |
S |
A |
-0.9530 |
|
| 68 |
G |
A |
-1.4481 |
|
| 69 |
T |
A |
-2.0835 |
|
| 70 |
D |
A |
-2.8793 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9327 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-1.0227 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.8278 |
|
| 77 |
S |
A |
-2.4477 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.3575 |
|
| 80 |
S |
A |
-2.1862 |
|
| 81 |
E |
A |
-2.0136 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
-1.6060 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-1.1438 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.1155 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.3335 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.3800 |
|
| 92 |
N |
A |
-1.5547 |
|
| 93 |
N |
A |
-1.1139 |
|
| 94 |
W |
A |
0.0840 |
|
| 95 |
P |
A |
-0.1310 |
|
| 96 |
T |
A |
-0.4793 |
|
| 97 |
T |
A |
0.3016 |
|
| 98 |
F |
A |
1.4324 |
|
| 99 |
G |
A |
0.6758 |
|
| 100 |
A |
A |
0.5689 |
|
| 101 |
G |
A |
0.2252 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.7784 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.2657 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.8237 |
|
| 108 |
R |
A |
-1.3376 |
|
| 109 |
T |
A |
-0.2186 |
|
| 110 |
V |
A |
0.2074 |
|
| 111 |
A |
A |
-0.1550 |
|
| 112 |
A |
A |
-0.2045 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1059 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.3396 |
|
| 117 |
I |
A |
1.2843 |
|
| 118 |
F |
A |
1.4513 |
|
| 119 |
P |
A |
-0.0936 |
|
| 120 |
P |
A |
-0.7371 |
|
| 121 |
S |
A |
-1.7857 |
|
| 122 |
D |
A |
-3.2057 |
|
| 123 |
E |
A |
-3.4138 |
|
| 124 |
Q |
A |
-2.5001 |
|
| 125 |
L |
A |
-2.5911 |
|
| 126 |
K |
A |
-3.0045 |
|
| 127 |
S |
A |
-1.9156 |
|
| 128 |
G |
A |
-1.3732 |
|
| 129 |
T |
A |
-1.1947 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0238 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.6930 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.5581 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.5368 |
|
| 138 |
N |
A |
-1.2822 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
-1.2627 |
|
| 141 |
P |
A |
-1.7950 |
|
| 142 |
R |
A |
-3.1031 |
|
| 143 |
E |
A |
-3.2206 |
|
| 144 |
A |
A |
-2.3045 |
|
| 145 |
K |
A |
-2.1970 |
|
| 146 |
V |
A |
-1.1067 |
|
| 147 |
Q |
A |
-0.7546 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.5501 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.5349 |
|
| 152 |
N |
A |
-1.3103 |
|
| 153 |
A |
A |
-0.1246 |
|
| 154 |
L |
A |
0.7742 |
|
| 155 |
Q |
A |
-0.1700 |
|
| 156 |
S |
A |
-0.4027 |
|
| 157 |
G |
A |
-1.0062 |
|
| 158 |
N |
A |
-0.9750 |
|
| 159 |
S |
A |
-1.4160 |
|
| 160 |
Q |
A |
-2.2909 |
|
| 161 |
E |
A |
-2.3446 |
|
| 162 |
S |
A |
-1.3937 |
|
| 163 |
V |
A |
-0.8630 |
|
| 164 |
T |
A |
-1.2826 |
|
| 165 |
E |
A |
-2.3759 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.3608 |
|
| 168 |
S |
A |
-2.4363 |
|
| 169 |
K |
A |
-2.7570 |
|
| 170 |
D |
A |
-2.1483 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-0.9980 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4689 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.5816 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.4187 |
|
| 181 |
L |
A |
-0.8044 |
|
| 182 |
S |
A |
-1.1954 |
|
| 183 |
K |
A |
-2.2959 |
|
| 184 |
A |
A |
-2.1207 |
|
| 185 |
D |
A |
-2.8131 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.7626 |
|
| 188 |
K |
A |
-3.7830 |
|
| 189 |
H |
A |
-3.0761 |
|
| 190 |
K |
A |
-3.1611 |
|
| 191 |
V |
A |
-1.3844 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-1.0090 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.2097 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.5818 |
|
| 200 |
G |
A |
-0.4000 |
|
| 201 |
L |
A |
-0.1929 |
|
| 202 |
S |
A |
-0.4335 |
|
| 203 |
S |
A |
-0.4102 |
|
| 204 |
P |
A |
-0.5374 |
|
| 205 |
V |
A |
-0.0779 |
|
| 206 |
T |
A |
-0.3472 |
|
| 207 |
K |
A |
-0.2126 |
|
| 208 |
S |
A |
-0.3736 |
|
| 209 |
F |
A |
-0.7512 |
|
| 210 |
N |
A |
-2.0797 |
|
| 211 |
R |
A |
-2.4903 |
|
| 212 |
G |
A |
-1.3421 |
|