Project name: 5esq:B

Chain sequence(s)	B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8103
• Maximal score value: 2.5288
• Average score: -0.534
• Total score value: -114.8196

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4419
2	V	B	-0.8162
3	Q	B	-1.5639
4	L	B	0.0000
5	K	B	-2.1499
6	Q	B	0.0000
7	S	B	-0.7993
8	G	B	-0.9279
9	P	B	-0.4382
10	G	B	-0.3605
11	L	B	-0.1182
12	V	B	0.0000
13	Q	B	-1.7071
14	P	B	-1.4689
15	S	B	-1.6707
16	Q	B	-2.0745
17	S	B	-1.9719
18	L	B	0.0000
19	S	B	-0.9246
20	I	B	0.0000
21	T	B	-0.6413
22	C	B	0.0000
23	T	B	-1.1599
24	V	B	0.0000
25	S	B	-1.1849
26	G	B	-0.9625
27	F	B	-0.5059
28	S	B	-0.8245
29	L	B	0.0000
30	T	B	-0.8894
31	N	B	-0.8581
32	Y	B	0.3751
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.3053
40	S	B	-0.9638
41	P	B	-1.0967
42	G	B	-1.6288
43	K	B	-2.0614
44	G	B	-0.6682
45	L	B	0.7167
46	E	B	0.0575
47	W	B	0.3861
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.6011
53	S	B	-0.6406
54	G	B	-1.1329
55	G	B	-1.4801
56	N	B	-1.9424
57	T	B	-1.5195
58	D	B	-1.5492
59	Y	B	-0.6682
60	N	B	-0.6348
61	T	B	-0.5096
62	P	B	-0.4571
63	F	B	0.0000
64	T	B	-0.6002
65	S	B	-0.6981
66	R	B	-1.2938
67	L	B	0.0000
68	S	B	-1.3291
69	I	B	0.0000
70	N	B	-1.8491
71	K	B	-1.5282
72	D	B	-1.8653
73	N	B	-2.1328
74	S	B	-1.6884
75	K	B	-2.3688
76	S	B	-1.5823
77	Q	B	-1.5764
78	V	B	0.0000
79	F	B	-0.6332
80	F	B	0.0000
81	K	B	-2.0160
82	M	B	0.0000
83	N	B	-2.3690
84	S	B	-1.7158
85	L	B	0.0000
86	Q	B	-2.1351
87	S	B	-1.5241
88	N	B	-2.0424
89	D	B	0.0000
90	T	B	-0.6833
91	A	B	0.0000
92	I	B	0.5400
93	Y	B	0.0000
94	Y	B	-0.0666
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.0994
100	T	B	0.9925
101	Y	B	1.8072
102	Y	B	1.5482
103	D	B	0.3495
104	Y	B	0.3290
105	E	B	-0.9895
106	F	B	0.0467
107	A	B	0.4067
108	Y	B	0.3344
109	W	B	0.0349
110	G	B	0.0000
111	Q	B	-1.4461
112	G	B	-0.6098
113	T	B	0.0000
114	L	B	0.3797
115	V	B	0.0000
116	T	B	0.0000
117	V	B	0.0000
118	S	B	-0.6268
119	A	B	-0.4329
120	A	B	-0.3432
121	S	B	-0.5358
122	T	B	-0.7126
123	K	B	-1.1857
124	G	B	-1.4495
125	P	B	0.0000
126	S	B	-0.0760
127	V	B	0.0000
128	F	B	0.8859
129	P	B	-0.1002
130	L	B	0.3373
131	A	B	-0.9049
132	P	B	0.0000
133	S	B	-0.7311
139	G	B	-0.7647
140	G	B	-0.8738
141	T	B	-0.6262
142	A	B	0.0000
143	A	B	0.0825
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.6749
148	V	B	0.0000
149	K	B	-0.2465
150	D	B	-0.6016
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.1770
155	P	B	-0.4578
156	V	B	-0.5726
157	T	B	-0.5652
158	V	B	-0.2700
159	S	B	-0.5045
160	W	B	0.0000
161	N	B	-0.8357
162	S	B	-0.6960
163	G	B	-0.5876
164	A	B	-0.2603
165	L	B	-0.0407
166	T	B	-0.3135
167	S	B	-0.3293
168	G	B	-0.3660
169	V	B	-0.0950
170	H	B	-0.5674
171	T	B	0.0844
172	F	B	0.9461
173	P	B	0.7387
174	A	B	1.3260
175	V	B	2.5288
176	L	B	2.1736
177	Q	B	0.6915
178	S	B	0.0876
179	S	B	-0.2156
180	G	B	0.2124
181	L	B	0.3117
182	Y	B	0.8463
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6292
186	S	B	0.0000
187	V	B	0.3425
188	V	B	0.0000
189	T	B	-0.2139
190	V	B	0.0000
191	P	B	-0.6497
192	S	B	-0.6988
193	S	B	-0.6300
194	S	B	-0.6261
195	L	B	-0.8092
196	G	B	-0.9583
197	T	B	-0.7404
198	Q	B	-1.0566
199	T	B	-1.1226
200	Y	B	0.0000
201	I	B	-1.4069
202	C	B	0.0000
203	N	B	-1.5142
204	V	B	0.0000
205	N	B	-1.9695
206	H	B	0.0000
207	K	B	-2.8103
208	P	B	-1.5732
209	S	B	-1.8475
210	N	B	-2.5881
211	T	B	-2.0517
212	K	B	-2.7283
213	V	B	-1.7060
214	D	B	-2.6230
215	K	B	-2.1747
216	R	B	-2.6665
217	V	B	0.0000
218	E	B	-2.7654
219	P	B	-1.8331
220	K	B	-2.2296