Project name: 3nfp:A
Status: done
submitted: 2019-03-20 15:36:09, status changed: 2019-03-20 17:18:47
Settings
|
Chain sequence(s)
|
A: QVQLVQSGAEVKKPGSSVKVSCKASGYTFTSYRMHWVRQAPGQGLEWIGYINPSTGYTEYNQKFKDKATITADESTNTAYMELSSLRSEDTAVYYCARGGGVFDYWGQGTLVTVSSASTKGPSVFPLAPSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7786
-
Maximal score value
-
2.3388
-
Average score
-
-0.6178
-
Total score value
-
-131.5964
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
A |
-1.5371 |
|
| 2 |
V |
A |
-1.0047 |
|
| 3 |
Q |
A |
-1.6300 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
V |
A |
-0.6850 |
|
| 6 |
Q |
A |
-0.6563 |
|
| 7 |
S |
A |
-0.8294 |
|
| 8 |
G |
A |
-0.5996 |
|
| 9 |
A |
A |
0.1892 |
|
| 10 |
E |
A |
-0.1530 |
|
| 11 |
V |
A |
1.0569 |
|
| 12 |
K |
A |
-0.6734 |
|
| 13 |
K |
A |
-1.6089 |
|
| 14 |
P |
A |
-1.6785 |
|
| 15 |
G |
A |
-1.4167 |
|
| 16 |
S |
A |
-1.0902 |
|
| 17 |
S |
A |
-1.1787 |
|
| 18 |
V |
A |
0.0000 |
|
| 19 |
K |
A |
-2.2795 |
|
| 20 |
V |
A |
0.0000 |
|
| 21 |
S |
A |
-0.8588 |
|
| 22 |
C |
A |
0.0000 |
|
| 23 |
K |
A |
-1.6388 |
|
| 24 |
A |
A |
0.0000 |
|
| 25 |
S |
A |
-1.1524 |
|
| 26 |
G |
A |
-1.0408 |
|
| 27 |
Y |
A |
-0.3304 |
|
| 28 |
T |
A |
-0.2684 |
|
| 29 |
F |
A |
0.0000 |
|
| 30 |
T |
A |
-0.8450 |
|
| 31 |
S |
A |
-0.3438 |
|
| 32 |
Y |
A |
-0.4368 |
|
| 33 |
R |
A |
-1.2185 |
|
| 34 |
M |
A |
0.0000 |
|
| 35 |
H |
A |
-0.2420 |
|
| 36 |
W |
A |
0.0000 |
|
| 37 |
V |
A |
0.0000 |
|
| 38 |
R |
A |
-0.3397 |
|
| 39 |
Q |
A |
-0.8046 |
|
| 40 |
A |
A |
-1.1621 |
|
| 41 |
P |
A |
-0.9219 |
|
| 42 |
G |
A |
-1.2124 |
|
| 43 |
Q |
A |
-1.6838 |
|
| 44 |
G |
A |
-0.8620 |
|
| 45 |
L |
A |
0.3070 |
|
| 46 |
E |
A |
-0.7717 |
|
| 47 |
W |
A |
-0.1972 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
G |
A |
0.0000 |
|
| 50 |
Y |
A |
-0.3934 |
|
| 51 |
I |
A |
0.0000 |
|
| 52 |
N |
A |
-0.6261 |
|
| 53 |
P |
A |
-1.0214 |
|
| 54 |
S |
A |
-0.7454 |
|
| 55 |
T |
A |
-0.0793 |
|
| 56 |
G |
A |
-0.0791 |
|
| 57 |
Y |
A |
0.7154 |
|
| 58 |
T |
A |
-0.1405 |
|
| 59 |
E |
A |
-1.0621 |
|
| 60 |
Y |
A |
-1.7034 |
|
| 61 |
N |
A |
-2.2782 |
|
| 62 |
Q |
A |
-2.9755 |
|
| 63 |
K |
A |
-3.3681 |
|
| 64 |
F |
A |
0.0000 |
|
| 65 |
K |
A |
-3.7786 |
|
| 66 |
D |
A |
-3.2235 |
|
| 67 |
K |
A |
-2.2389 |
|
| 68 |
A |
A |
0.0000 |
|
| 69 |
T |
A |
-1.2869 |
|
| 70 |
I |
A |
0.0000 |
|
| 71 |
T |
A |
-0.2025 |
|
| 72 |
A |
A |
-0.8592 |
|
| 73 |
D |
A |
-1.6625 |
|
| 74 |
E |
A |
-2.3762 |
|
| 75 |
S |
A |
-1.3898 |
|
| 76 |
T |
A |
-1.2647 |
|
| 77 |
N |
A |
-1.6487 |
|
| 78 |
T |
A |
0.0000 |
|
| 79 |
A |
A |
0.0000 |
|
| 80 |
Y |
A |
-0.6989 |
|
| 81 |
M |
A |
0.0000 |
|
| 82 |
E |
A |
-1.9068 |
|
| 83 |
L |
A |
0.0000 |
|
| 84 |
S |
A |
-1.4084 |
|
| 85 |
S |
A |
-1.3495 |
|
| 86 |
L |
A |
0.0000 |
|
| 87 |
R |
A |
-2.6919 |
|
| 88 |
S |
A |
-2.1428 |
|
| 89 |
E |
A |
-2.4394 |
|
| 90 |
D |
A |
0.0000 |
|
| 91 |
T |
A |
-0.6508 |
|
| 92 |
A |
A |
0.0000 |
|
| 93 |
V |
A |
0.3036 |
|
| 94 |
Y |
A |
0.0000 |
|
| 95 |
Y |
A |
-0.0171 |
|
| 96 |
C |
A |
0.0000 |
|
| 97 |
A |
A |
0.0000 |
|
| 98 |
R |
A |
-0.3787 |
|
| 99 |
G |
A |
0.0000 |
|
| 100 |
G |
A |
-0.5884 |
|
| 101 |
G |
A |
-0.0206 |
|
| 102 |
V |
A |
1.3232 |
|
| 103 |
F |
A |
0.5578 |
|
| 104 |
D |
A |
-0.8700 |
|
| 105 |
Y |
A |
-0.0961 |
|
| 106 |
W |
A |
-0.1210 |
|
| 107 |
G |
A |
-0.6432 |
|
| 108 |
Q |
A |
-1.2100 |
|
| 109 |
G |
A |
-0.3463 |
|
| 110 |
T |
A |
0.0000 |
|
| 111 |
L |
A |
1.2113 |
|
| 112 |
V |
A |
0.0000 |
|
| 113 |
T |
A |
0.0429 |
|
| 114 |
V |
A |
0.0000 |
|
| 115 |
S |
A |
-0.9630 |
|
| 116 |
S |
A |
-1.0130 |
|
| 117 |
A |
A |
-0.6232 |
|
| 118 |
S |
A |
-0.4923 |
|
| 119 |
T |
A |
-0.8108 |
|
| 120 |
K |
A |
-1.3317 |
|
| 121 |
G |
A |
-1.6968 |
|
| 122 |
P |
A |
-1.0657 |
|
| 123 |
S |
A |
-0.4358 |
|
| 124 |
V |
A |
0.0000 |
|
| 125 |
F |
A |
0.7141 |
|
| 126 |
P |
A |
0.0348 |
|
| 127 |
L |
A |
0.5650 |
|
| 128 |
A |
A |
-0.1875 |
|
| 129 |
P |
A |
-0.3933 |
|
| 133 |
S |
A |
-0.6361 |
|
| 134 |
T |
A |
-0.7088 |
|
| 135 |
S |
A |
-0.7254 |
|
| 136 |
G |
A |
-0.9408 |
|
| 137 |
G |
A |
-0.8985 |
|
| 138 |
T |
A |
-0.5895 |
|
| 139 |
A |
A |
-0.3795 |
|
| 140 |
A |
A |
0.1069 |
|
| 141 |
L |
A |
0.0000 |
|
| 142 |
G |
A |
0.0000 |
|
| 143 |
C |
A |
0.0000 |
|
| 144 |
L |
A |
0.6461 |
|
| 145 |
V |
A |
0.0000 |
|
| 146 |
K |
A |
-0.8179 |
|
| 147 |
D |
A |
-1.7265 |
|
| 148 |
Y |
A |
0.0000 |
|
| 149 |
F |
A |
0.0000 |
|
| 150 |
P |
A |
-0.9851 |
|
| 151 |
E |
A |
-1.5944 |
|
| 152 |
P |
A |
-1.2325 |
|
| 153 |
V |
A |
-0.5847 |
|
| 154 |
T |
A |
-0.3525 |
|
| 155 |
V |
A |
-0.1677 |
|
| 156 |
S |
A |
-0.3731 |
|
| 157 |
W |
A |
0.0000 |
|
| 158 |
N |
A |
-0.7830 |
|
| 159 |
S |
A |
-0.6666 |
|
| 160 |
G |
A |
-0.5711 |
|
| 161 |
A |
A |
-0.2244 |
|
| 162 |
L |
A |
0.0303 |
|
| 163 |
T |
A |
-0.2272 |
|
| 164 |
S |
A |
-0.3409 |
|
| 165 |
G |
A |
-0.4506 |
|
| 166 |
V |
A |
-0.0842 |
|
| 167 |
H |
A |
-0.4212 |
|
| 168 |
T |
A |
0.3905 |
|
| 169 |
F |
A |
1.3213 |
|
| 170 |
P |
A |
0.9439 |
|
| 171 |
A |
A |
1.1291 |
|
| 172 |
V |
A |
2.3388 |
|
| 173 |
L |
A |
1.6672 |
|
| 174 |
Q |
A |
-0.3030 |
|
| 175 |
S |
A |
-0.3797 |
|
| 176 |
S |
A |
-0.6298 |
|
| 177 |
G |
A |
-0.1963 |
|
| 178 |
L |
A |
-0.3245 |
|
| 179 |
Y |
A |
0.0160 |
|
| 180 |
S |
A |
0.2445 |
|
| 181 |
L |
A |
0.8585 |
|
| 182 |
S |
A |
0.7402 |
|
| 183 |
S |
A |
0.0000 |
|
| 184 |
V |
A |
0.5575 |
|
| 185 |
V |
A |
0.0000 |
|
| 186 |
T |
A |
-0.1982 |
|
| 187 |
V |
A |
0.0000 |
|
| 188 |
P |
A |
-0.5854 |
|
| 189 |
S |
A |
0.0000 |
|
| 190 |
S |
A |
-0.8069 |
|
| 191 |
S |
A |
-0.7141 |
|
| 192 |
L |
A |
0.0000 |
|
| 193 |
G |
A |
-1.1047 |
|
| 194 |
T |
A |
-0.7832 |
|
| 195 |
Q |
A |
-1.3380 |
|
| 196 |
T |
A |
-1.1502 |
|
| 197 |
Y |
A |
0.0000 |
|
| 198 |
I |
A |
-1.3412 |
|
| 199 |
C |
A |
0.0000 |
|
| 200 |
N |
A |
-1.6066 |
|
| 201 |
V |
A |
0.0000 |
|
| 202 |
N |
A |
-1.6513 |
|
| 203 |
H |
A |
0.0000 |
|
| 204 |
K |
A |
-2.7495 |
|
| 205 |
P |
A |
-1.7371 |
|
| 206 |
S |
A |
-1.8091 |
|
| 207 |
N |
A |
-2.4566 |
|
| 208 |
T |
A |
-1.9723 |
|
| 209 |
K |
A |
-2.5252 |
|
| 210 |
V |
A |
-1.4178 |
|
| 211 |
D |
A |
-2.6820 |
|
| 212 |
K |
A |
-2.0747 |
|
| 213 |
K |
A |
-2.6626 |
|
| 214 |
V |
A |
0.0000 |
|
| 215 |
E |
A |
-2.3892 |
|
| 216 |
P |
A |
-1.1879 |
|