Project name: 5dk3:A

Chain sequence(s)	A: EIVLTQSPATLSLSPGERATLSCRASKGVSTSGYSYLHWYQQKPGQAPRLLIYLASYLESGVPARFSGSGSGTDFTLTISSLEPEDFAVYYCQHSRDLPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3619
• Maximal score value: 2.0155
• Average score: -0.7063
• Total score value: -153.9819

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-1.2934
2	I	A	0.0000
3	V	A	1.0837
4	L	A	0.0000
5	T	A	-0.2786
6	Q	A	-0.3267
7	S	A	-0.6943
8	P	A	-0.4098
9	A	A	-0.5064
10	T	A	-0.6392
11	L	A	-0.4433
12	S	A	-0.6849
13	L	A	-1.1279
14	S	A	-1.5362
15	P	A	-1.8508
16	G	A	-1.8538
17	E	A	-2.5445
18	R	A	-2.8165
19	A	A	0.0000
20	T	A	-0.6580
21	L	A	0.0000
22	S	A	-0.7803
23	C	A	0.0000
24	R	A	-2.0118
25	A	A	0.0000
26	S	A	-1.1278
27	K	A	-2.4043
28	G	A	-1.6542
29	V	A	0.0000
30	S	A	-0.4860
31	T	A	-0.2528
32	S	A	-0.2384
33	G	A	-0.2033
34	Y	A	0.3979
35	S	A	0.0000
36	Y	A	0.0724
37	L	A	0.0000
38	H	A	0.7695
39	W	A	0.0000
40	Y	A	0.1908
41	Q	A	0.0000
42	Q	A	-1.2132
43	K	A	-1.7793
44	P	A	-1.5142
45	G	A	-1.4764
46	Q	A	-1.8217
47	A	A	-1.0410
48	P	A	-0.9432
49	R	A	-0.9980
50	L	A	0.0185
51	L	A	0.0000
52	I	A	0.0000
53	Y	A	1.0837
54	L	A	0.9418
55	A	A	0.0000
56	S	A	0.3562
57	Y	A	1.0347
58	L	A	0.8071
59	E	A	-0.1824
60	S	A	-0.4209
61	G	A	-0.5885
62	V	A	0.0000
63	P	A	-0.2955
64	A	A	-0.2489
65	R	A	-0.7772
66	F	A	0.0000
67	S	A	-0.1840
68	G	A	-0.0071
69	S	A	-0.6165
70	G	A	-1.1169
71	S	A	-0.9135
72	G	A	-1.1120
73	T	A	-1.8168
74	D	A	-2.3239
75	F	A	0.0000
76	T	A	-0.7821
77	L	A	0.0000
78	T	A	-0.6863
79	I	A	0.0000
80	S	A	-1.6935
81	S	A	-1.8552
82	L	A	0.0000
83	E	A	-2.1957
84	P	A	-2.2414
85	E	A	-2.3927
86	D	A	0.0000
87	F	A	-1.5329
88	A	A	0.0000
89	V	A	0.0000
90	Y	A	0.0000
91	Y	A	0.1759
92	C	A	0.0000
93	Q	A	0.0000
94	H	A	0.0000
95	S	A	0.0249
96	R	A	-1.3466
97	D	A	-1.1588
98	L	A	0.7593
99	P	A	0.6998
100	L	A	1.6539
101	T	A	1.3513
102	F	A	2.0155
103	G	A	0.0000
104	G	A	-0.0770
105	G	A	-0.4007
106	T	A	0.0000
107	K	A	-1.6215
108	V	A	0.0000
109	E	A	-1.4392
110	I	A	0.0000
111	K	A	-1.1927
112	R	A	-0.9942
113	T	A	-0.1061
114	V	A	0.2082
115	A	A	-0.2154
116	A	A	-0.2436
117	P	A	0.0000
118	S	A	-0.0046
119	V	A	0.4486
120	F	A	1.3991
121	I	A	1.2362
122	F	A	1.5280
123	P	A	0.3243
124	P	A	-0.5773
125	S	A	-1.6991
126	D	A	-3.1912
127	E	A	-3.3619
128	Q	A	-2.4559
129	L	A	-2.5592
130	K	A	-3.0199
131	S	A	-1.9461
132	G	A	-1.3802
133	T	A	-1.0398
134	A	A	0.0000
135	S	A	0.0430
136	V	A	0.0000
137	V	A	0.7359
138	C	A	0.0000
139	L	A	0.5818
140	L	A	0.0000
141	N	A	-0.4619
142	N	A	-1.2219
143	F	A	0.0000
144	Y	A	0.0000
145	P	A	-1.7379
146	R	A	-3.1127
147	E	A	-3.2427
148	A	A	-2.2508
149	K	A	-2.2411
150	V	A	-1.1234
151	Q	A	-0.7476
152	W	A	0.0000
153	K	A	-0.7181
154	V	A	0.0000
155	D	A	-1.5950
156	N	A	-1.4011
157	A	A	-0.2397
158	L	A	0.6928
159	Q	A	-0.1225
160	S	A	-0.4170
161	G	A	-0.9713
162	N	A	-0.9340
163	S	A	-1.4328
164	Q	A	-2.2892
165	E	A	-2.3439
166	S	A	-1.3227
167	V	A	-0.7837
168	T	A	-1.2430
169	E	A	-2.3513
170	Q	A	0.0000
171	D	A	-2.4000
172	S	A	-2.4964
173	K	A	-2.8088
174	D	A	-2.1187
175	S	A	0.0000
176	T	A	0.0000
177	Y	A	-1.5372
178	S	A	-0.9041
179	L	A	0.0000
180	S	A	-0.4567
181	S	A	0.0000
182	T	A	-0.6178
183	L	A	0.0000
184	T	A	-0.4016
185	L	A	-0.7109
186	S	A	-1.1207
187	K	A	-2.1297
188	A	A	-1.8789
189	D	A	-2.6085
190	Y	A	0.0000
191	E	A	-3.0703
192	K	A	-3.3453
193	H	A	-2.5385
194	K	A	-2.2790
195	V	A	-0.8176
196	Y	A	0.0000
197	A	A	0.0000
198	C	A	0.0000
199	E	A	-0.8978
200	V	A	0.0000
201	T	A	-1.1634
202	H	A	0.0000
203	Q	A	-1.6157
204	G	A	-0.4608
205	L	A	-0.2498
206	S	A	-0.4818
207	S	A	-0.4053
208	P	A	-0.4779
209	V	A	-0.0268
210	T	A	-0.4195
211	K	A	-0.3826
212	S	A	-0.2938
213	F	A	-0.4282
214	N	A	-1.3245
215	R	A	-1.8270
216	G	A	-1.6305
217	E	A	-2.0088
218	C	A	-0.3514