Project name: 6b3s:H

Chain sequence(s)	H: QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGDYYWSWIRQPPGKGLEWIGYIYYSGSTDYNPSLKSRVTMSVDTSKNQFSLKVNSVTAADTAVYYCARVSIFGVGTFDYWGQGTLVTVSSASTKGPSVFPLAPTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7682
• Maximal score value: 2.3214
• Average score: -0.4193
• Total score value: -89.3019

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.6391
2	V	H	-1.0771
3	Q	H	-1.7614
4	L	H	0.0000
5	Q	H	-1.4500
6	E	H	0.0000
7	S	H	-0.6917
8	G	H	-0.4929
9	P	H	-0.2493
10	G	H	0.1270
11	L	H	0.2234
12	V	H	0.0000
13	K	H	-2.1013
14	P	H	-1.5095
15	S	H	-1.4940
16	Q	H	-2.0605
17	T	H	-1.6017
18	L	H	0.0000
19	S	H	-0.7799
20	L	H	0.0000
21	T	H	-0.5225
22	C	H	0.0000
23	T	H	-1.0798
24	V	H	0.0000
25	S	H	-1.2902
26	G	H	-1.3980
27	G	H	-1.1113
28	S	H	-0.8031
29	I	H	0.0000
30	S	H	-0.0665
31	S	H	-0.1166
32	G	H	0.1423
33	D	H	0.0083
34	Y	H	0.5803
35	Y	H	0.6529
36	W	H	0.0000
37	S	H	0.0000
38	W	H	0.0000
39	I	H	0.0000
40	R	H	0.0000
41	Q	H	-0.3544
42	P	H	-0.7023
43	P	H	-0.8657
44	G	H	-1.4319
45	K	H	-2.0596
46	G	H	-0.8942
47	L	H	0.6761
48	E	H	0.0585
49	W	H	0.5468
50	I	H	0.0000
51	G	H	0.0000
52	Y	H	0.0391
53	I	H	0.0000
54	Y	H	0.4312
55	Y	H	0.9017
56	S	H	0.0525
57	G	H	-0.1675
58	S	H	-0.4267
59	T	H	-0.5020
60	D	H	-1.0352
61	Y	H	-0.5067
62	N	H	-0.7103
63	P	H	-1.0644
64	S	H	-0.8388
65	L	H	0.0000
66	K	H	-1.9997
67	S	H	-1.3186
68	R	H	-1.4286
69	V	H	0.0000
70	T	H	-0.6923
71	M	H	0.0000
72	S	H	-0.1630
73	V	H	0.0041
74	D	H	-1.2004
75	T	H	-0.9734
76	S	H	-1.3662
77	K	H	-2.1465
78	N	H	-1.4829
79	Q	H	-1.1538
80	F	H	0.0000
81	S	H	-0.4000
82	L	H	0.0000
83	K	H	-1.3193
84	V	H	0.0000
85	N	H	-1.5875
86	S	H	-1.3036
87	V	H	0.0000
88	T	H	-0.7144
89	A	H	-0.2304
90	A	H	0.0581
91	D	H	0.0000
92	T	H	0.1581
93	A	H	0.0000
94	V	H	0.5121
95	Y	H	0.0000
96	Y	H	0.2063
97	C	H	0.0000
98	A	H	0.0000
99	R	H	0.2006
100	V	H	0.0000
101	S	H	0.9698
102	I	H	1.5430
103	F	H	2.1109
104	G	H	1.1945
105	V	H	1.8225
106	G	H	1.0109
107	T	H	0.6495
108	F	H	0.7242
109	D	H	0.0590
110	Y	H	0.3105
111	W	H	0.0471
112	G	H	-0.8488
113	Q	H	-1.4324
114	G	H	0.0000
115	T	H	-0.0719
116	L	H	0.7222
117	V	H	0.0000
118	T	H	-0.0738
119	V	H	0.0000
120	S	H	-0.6586
121	S	H	-0.8561
122	A	H	-0.6776
123	S	H	-0.8462
124	T	H	-1.1273
125	K	H	-1.9396
126	G	H	-1.9476
127	P	H	0.0000
128	S	H	-0.2450
129	V	H	0.0000
130	F	H	0.9898
131	P	H	0.0352
132	L	H	0.4762
133	A	H	-0.5285
134	P	H	-0.5540
142	T	H	-0.2648
143	A	H	-0.2133
144	A	H	0.0659
145	L	H	0.0000
146	G	H	0.0000
147	C	H	0.0000
148	L	H	0.6949
149	V	H	0.0000
150	K	H	-0.3895
151	D	H	-1.0220
152	Y	H	0.0000
153	F	H	0.0000
154	P	H	-1.2080
155	E	H	-0.8993
156	P	H	-1.0824
157	V	H	-0.5344
158	T	H	-0.3824
159	V	H	-0.2047
160	S	H	-0.4199
161	W	H	0.0000
162	N	H	-0.8608
163	S	H	-0.6907
164	G	H	-0.5346
165	A	H	-0.1884
166	L	H	0.0706
167	T	H	-0.1978
168	S	H	-0.3085
169	G	H	-0.4083
170	V	H	0.0604
171	H	H	-0.4935
172	T	H	0.1044
173	F	H	0.7994
174	P	H	0.5157
175	A	H	1.0452
176	V	H	2.3214
177	L	H	1.9878
178	Q	H	0.6516
179	S	H	0.1036
180	S	H	-0.2572
181	G	H	0.1010
182	L	H	0.0000
183	Y	H	0.3821
184	S	H	0.0000
185	L	H	0.0000
186	S	H	0.5905
187	S	H	0.0000
188	V	H	0.4741
189	V	H	0.0000
190	T	H	-0.2344
191	V	H	0.0000
192	P	H	-0.5402
193	S	H	-0.5185
194	S	H	-0.6211
195	S	H	-0.7240
196	L	H	-1.0042
197	G	H	-1.0575
198	T	H	-0.8134
199	Q	H	-1.4396
200	T	H	-1.2698
201	Y	H	0.0000
202	I	H	-1.5587
203	C	H	0.0000
204	N	H	-1.6423
205	V	H	0.0000
206	N	H	-1.7923
207	H	H	0.0000
208	K	H	-2.6653
209	P	H	-1.9025
210	S	H	-2.0602
211	N	H	-2.6451
212	T	H	-2.3370
213	K	H	-2.7247
214	V	H	-1.8940
215	D	H	-2.7682
216	K	H	-2.3225
217	K	H	-2.5920
218	V	H	0.0000
219	E	H	-2.5077
220	P	H	-1.1754