Project name: 6fbg:H

Chain sequence(s)	H: VPLVESGGGLVQPGGSLRLSCAVSGFTFSNYGMVWVRQAPGKGLEWVAYIDSDGDNTYYRDSVKGRFTISRDNAKSSLYLQMNSLRAEDTAVYYCTTGIVRPFLYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1653
• Maximal score value: 2.6143
• Average score: -0.4818
• Total score value: -104.5606

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	H	1.8917
3	P	H	0.9705
4	L	H	0.0000
5	V	H	1.7732
6	E	H	0.0000
7	S	H	-0.2181
8	G	H	-0.8088
9	G	H	-0.2455
10	G	H	0.0882
11	L	H	0.3154
12	V	H	-0.4461
13	Q	H	-1.5362
14	P	H	-1.6213
15	G	H	-1.3951
16	G	H	-1.0429
17	S	H	-1.0984
18	L	H	-1.0273
19	R	H	-2.0641
20	L	H	0.0000
21	S	H	-0.3174
22	C	H	0.0000
23	A	H	0.1575
24	V	H	0.0000
25	S	H	0.0041
26	G	H	0.2399
27	F	H	-0.2535
28	T	H	-0.5707
29	F	H	0.0000
30	S	H	-1.6555
31	N	H	-1.1682
32	Y	H	0.0000
33	G	H	0.0000
34	M	H	0.0000
35	V	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.3369
40	A	H	-0.9897
41	P	H	-0.8146
42	G	H	-1.3745
43	K	H	-2.0400
44	G	H	-0.9069
45	L	H	0.5935
46	E	H	-0.0786
47	W	H	0.4122
48	V	H	0.0000
49	A	H	0.0000
50	Y	H	0.5227
51	I	H	0.0000
52	D	H	-1.8227
53	S	H	-1.9787
54	D	H	-3.1601
55	G	H	-2.7040
56	D	H	-3.1653
57	N	H	-2.3089
58	T	H	-0.4393
59	Y	H	0.5971
60	Y	H	-0.3646
61	R	H	-1.3905
62	D	H	-2.5909
63	S	H	-1.9377
64	V	H	0.0000
65	K	H	-2.5888
66	G	H	-1.8494
67	R	H	-1.6371
68	F	H	0.0000
69	T	H	-0.6331
70	I	H	0.0000
71	S	H	-0.7595
72	R	H	-1.3842
73	D	H	-1.6008
74	N	H	-1.9041
75	A	H	-1.2704
76	K	H	-2.0892
77	S	H	-1.3254
78	S	H	0.0000
79	L	H	0.0000
80	Y	H	-0.4473
81	L	H	0.0000
82	Q	H	-1.1088
83	M	H	0.0000
84	N	H	-1.5634
85	S	H	-1.3840
86	L	H	0.0000
87	R	H	-2.7101
88	A	H	-1.9278
89	E	H	-2.3348
90	D	H	0.0000
91	T	H	-0.6949
92	A	H	0.0000
93	V	H	0.4916
94	Y	H	0.0000
95	Y	H	0.5385
96	C	H	0.0000
97	T	H	0.0000
98	T	H	0.0000
99	G	H	0.0000
100	I	H	2.3661
101	V	H	2.2186
102	R	H	0.5227
103	P	H	1.1887
104	F	H	2.0034
105	L	H	1.9271
106	Y	H	1.3724
107	W	H	1.3440
108	G	H	0.6076
109	Q	H	-0.3514
110	G	H	0.0410
111	T	H	0.3552
112	L	H	0.7171
113	V	H	0.0000
114	T	H	-0.2812
115	V	H	0.0000
116	S	H	-0.9409
117	S	H	-0.8170
118	A	H	-0.4668
119	S	H	-0.5634
120	T	H	-0.9763
121	K	H	-1.1682
122	G	H	-1.4708
123	P	H	0.0000
124	S	H	-0.0686
125	V	H	0.0000
126	F	H	1.2015
127	P	H	0.2388
128	L	H	0.2792
129	A	H	-0.8444
130	P	H	0.0000
131	S	H	-1.1084
132	S	H	-1.4934
133	K	H	-1.9434
134	S	H	-1.2250
135	T	H	-1.0255
136	S	H	-0.9580
137	G	H	-0.9370
138	G	H	-0.8798
139	T	H	-0.5736
140	A	H	0.0000
141	A	H	0.1244
142	L	H	0.0000
143	G	H	0.0000
144	C	H	0.0000
145	L	H	0.8202
146	V	H	0.0000
147	K	H	-0.4539
148	D	H	-0.7141
149	Y	H	0.0000
150	F	H	0.0000
151	P	H	0.0000
152	E	H	-1.1783
153	P	H	-1.1383
154	V	H	-0.6180
155	T	H	-0.3783
156	V	H	-0.1861
157	S	H	-0.3565
158	W	H	0.0000
159	N	H	-0.7223
160	S	H	-0.6760
161	G	H	-0.5804
162	A	H	-0.2515
163	L	H	-0.0206
164	T	H	-0.2614
165	S	H	-0.3677
166	G	H	-0.4649
167	V	H	0.0652
168	H	H	-0.2885
169	T	H	0.2752
170	F	H	1.1278
171	P	H	0.8104
172	A	H	1.1988
173	V	H	2.6143
174	L	H	2.2083
175	Q	H	0.7025
176	S	H	0.1159
177	S	H	-0.2421
178	G	H	0.1226
179	L	H	0.2988
180	Y	H	0.7203
181	S	H	0.0000
182	L	H	0.0000
183	S	H	0.5558
184	S	H	0.0000
185	V	H	0.5382
186	V	H	0.0000
187	T	H	-0.1876
188	V	H	0.0000
189	P	H	-0.6379
190	S	H	-0.6106
191	S	H	-0.6962
192	S	H	-0.5710
193	L	H	-0.5408
194	G	H	-0.9580
195	T	H	-0.6982
196	Q	H	-1.0931
197	T	H	-1.0812
198	Y	H	0.0000
199	I	H	-1.2645
200	C	H	0.0000
201	N	H	-1.5547
202	V	H	0.0000
203	N	H	-1.7459
204	H	H	0.0000
205	K	H	-2.8017
206	P	H	-1.6814
207	S	H	-1.8509
208	N	H	-2.5979
209	T	H	-2.0680
210	K	H	-2.7425
211	V	H	-1.7839
212	D	H	-2.7529
213	K	H	-2.2661
214	K	H	-2.5327
215	V	H	0.0000
216	E	H	-2.7662
217	P	H	-1.9878
218	K	H	-2.2890