| Chain sequence(s) |
H: QVQLVQSGAEVKKPGASVKVSCKASGYSFTNYYIHWVRQAPGQRLEWMGWINAGNGNTKYSQKFQGRVTITRDTSASTAYMELSSLRSEDTAVYYCVRRQRFPYYFDYWGQGTLVTVS L: EIVLTQSPATLSVSPGERATLSCRASQSVGTNVAWYQQKPGQAPRVLIYSTSSRATGITDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQFNKSPLTFGGGTKVEIK |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | E | L | -1.8867 | |
| 2 | I | L | 0.0000 | |
| 3 | V | L | 0.8491 | |
| 4 | L | L | 0.0000 | |
| 5 | T | L | -0.4111 | |
| 6 | Q | L | 0.0000 | |
| 7 | S | L | -0.5999 | |
| 8 | P | L | -0.3368 | |
| 9 | A | L | -0.3339 | |
| 10 | T | L | -0.6046 | |
| 11 | L | L | -0.3711 | |
| 12 | S | L | -0.6331 | |
| 13 | V | L | -0.7374 | |
| 14 | S | L | -1.1542 | |
| 15 | P | L | -1.8799 | |
| 16 | G | L | -2.3748 | |
| 17 | E | L | -2.6031 | |
| 18 | R | L | -3.0390 | |
| 19 | A | L | 0.0000 | |
| 20 | T | L | -0.5343 | |
| 21 | L | L | 0.0000 | |
| 22 | S | L | -0.9063 | |
| 23 | C | L | 0.0000 | |
| 24 | R | L | -1.9908 | |
| 25 | A | L | 0.0000 | |
| 26 | S | L | -0.8473 | |
| 27 | Q | L | -1.9995 | |
| 28 | S | L | -1.8304 | |
| 29 | V | L | 0.0000 | |
| 30 | G | L | -1.2207 | |
| 31 | T | L | -0.9383 | |
| 32 | N | L | -0.9366 | |
| 33 | V | L | 0.0000 | |
| 34 | A | L | 0.0000 | |
| 35 | W | L | 0.0000 | |
| 36 | Y | L | 0.0000 | |
| 37 | Q | L | 0.0000 | |
| 38 | Q | L | 0.0000 | |
| 39 | K | L | -1.5047 | |
| 40 | P | L | -1.0223 | |
| 41 | G | L | -1.3965 | |
| 42 | Q | L | -2.1992 | |
| 43 | A | L | -1.4885 | |
| 44 | P | L | 0.0000 | |
| 45 | R | L | -1.8093 | |
| 46 | V | L | -0.5011 | |
| 47 | L | L | 0.0000 | |
| 48 | I | L | 0.0000 | |
| 49 | Y | L | 0.1119 | |
| 50 | S | L | 0.0541 | |
| 51 | T | L | 0.0000 | |
| 52 | S | L | -0.5151 | |
| 53 | S | L | -0.3928 | |
| 54 | R | L | -0.8446 | |
| 55 | A | L | -0.4466 | |
| 56 | T | L | -0.3321 | |
| 57 | G | L | -0.6949 | |
| 58 | I | L | -0.6092 | |
| 59 | T | L | -1.0906 | |
| 60 | D | L | -2.0244 | |
| 61 | R | L | -1.8924 | |
| 62 | F | L | 0.0000 | |
| 63 | S | L | -0.7940 | |
| 64 | G | L | -0.3970 | |
| 65 | S | L | -0.7367 | |
| 66 | G | L | -1.2093 | |
| 67 | S | L | -1.2527 | |
| 68 | G | L | -1.4216 | |
| 69 | T | L | -1.9219 | |
| 70 | D | L | -2.7180 | |
| 71 | F | L | 0.0000 | |
| 72 | T | L | -0.8622 | |
| 73 | L | L | 0.0000 | |
| 74 | T | L | -0.7624 | |
| 75 | I | L | 0.0000 | |
| 76 | S | L | -2.5072 | |
| 77 | R | L | -3.2916 | |
| 78 | L | L | 0.0000 | |
| 79 | E | L | -2.7029 | |
| 80 | P | L | -1.7496 | |
| 81 | E | L | -2.2894 | |
| 82 | D | L | 0.0000 | |
| 83 | F | L | -0.7053 | |
| 84 | A | L | 0.0000 | |
| 85 | V | L | -0.4204 | |
| 86 | Y | L | 0.0000 | |
| 87 | Y | L | 0.0000 | |
| 88 | C | L | 0.0000 | |
| 89 | Q | L | 0.0000 | |
| 90 | Q | L | 0.0000 | |
| 91 | F | L | 0.0000 | |
| 92 | N | L | -2.3003 | |
| 93 | K | L | -2.8626 | |
| 94 | S | L | -1.7661 | |
| 95 | P | L | -1.6087 | |
| 96 | L | L | -0.5595 | |
| 97 | T | L | 0.0000 | |
| 98 | F | L | 0.0000 | |
| 99 | G | L | 0.0000 | |
| 100 | G | L | -0.9603 | |
| 101 | G | L | -0.8603 | |
| 102 | T | L | 0.0000 | |
| 103 | K | L | -0.9562 | |
| 104 | V | L | 0.0000 | |
| 105 | E | L | -0.9426 | |
| 106 | I | L | 0.4492 | |
| 107 | K | L | -1.0590 | |
| 1 | Q | H | -1.0511 | |
| 2 | V | H | -0.2799 | |
| 3 | Q | H | -0.5217 | |
| 4 | L | H | 0.0000 | |
| 5 | V | H | -0.5629 | |
| 6 | Q | H | -0.5695 | |
| 7 | S | H | -0.9062 | |
| 8 | G | H | -0.8475 | |
| 9 | A | H | -0.2523 | |
| 10 | E | H | -1.0930 | |
| 11 | V | H | 0.4996 | |
| 12 | K | H | -1.1654 | |
| 13 | K | H | -2.2208 | |
| 14 | P | H | -2.0059 | |
| 15 | G | H | -1.5888 | |
| 16 | A | H | -1.0610 | |
| 17 | S | H | -1.5291 | |
| 18 | V | H | 0.0000 | |
| 19 | K | H | -2.1899 | |
| 20 | V | H | 0.0000 | |
| 21 | S | H | -0.8078 | |
| 22 | C | H | 0.0000 | |
| 23 | K | H | -1.1333 | |
| 24 | A | H | 0.0000 | |
| 25 | S | H | -0.7224 | |
| 26 | G | H | -0.6315 | |
| 27 | Y | H | -0.3741 | |
| 28 | S | H | -0.5769 | |
| 29 | F | H | 0.0000 | |
| 30 | T | H | -1.0852 | |
| 31 | N | H | -1.6814 | |
| 32 | Y | H | 0.0000 | |
| 33 | Y | H | -0.5109 | |
| 34 | I | H | 0.0000 | |
| 35 | H | H | 0.0000 | |
| 36 | W | H | 0.0000 | |
| 37 | V | H | 0.0000 | |
| 38 | R | H | 0.0000 | |
| 39 | Q | H | -0.7549 | |
| 40 | A | H | -1.1143 | |
| 41 | P | H | -1.2122 | |
| 42 | G | H | -1.4446 | |
| 43 | Q | H | -2.2293 | |
| 44 | R | H | -2.1264 | |
| 45 | L | H | 0.0000 | |
| 46 | E | H | -0.7011 | |
| 47 | W | H | 0.0000 | |
| 48 | M | H | 0.0000 | |
| 49 | G | H | 0.0000 | |
| 50 | W | H | -0.1859 | |
| 51 | I | H | 0.0000 | |
| 52 | N | H | -1.2538 | |
| 52A | A | H | 0.0000 | |
| 53 | G | H | -1.6691 | |
| 54 | N | H | -2.0768 | |
| 55 | G | H | -1.6459 | |
| 56 | N | H | -2.1749 | |
| 57 | T | H | -1.4748 | |
| 58 | K | H | -1.7914 | |
| 59 | Y | H | -0.8925 | |
| 60 | S | H | -1.6928 | |
| 61 | Q | H | -2.6436 | |
| 62 | K | H | -2.7867 | |
| 63 | F | H | 0.0000 | |
| 64 | Q | H | -2.7111 | |
| 65 | G | H | -2.1482 | |
| 66 | R | H | -2.3464 | |
| 67 | V | H | -1.2230 | |
| 68 | T | H | -0.7451 | |
| 69 | I | H | -0.4086 | |
| 70 | T | H | -0.5882 | |
| 71 | R | H | -1.1486 | |
| 72 | D | H | -1.1544 | |
| 73 | T | H | -0.7461 | |
| 74 | S | H | -0.5336 | |
| 75 | A | H | -0.6006 | |
| 76 | S | H | -0.7257 | |
| 77 | T | H | 0.0000 | |
| 78 | A | H | 0.0000 | |
| 79 | Y | H | -0.7670 | |
| 80 | M | H | 0.0000 | |
| 81 | E | H | -1.7021 | |
| 82 | L | H | 0.0000 | |
| 82A | S | H | -1.4832 | |
| 82B | S | H | -1.3548 | |
| 82C | L | H | 0.0000 | |
| 83 | R | H | -2.8910 | |
| 84 | S | H | -2.3026 | |
| 85 | E | H | -2.5140 | |
| 86 | D | H | 0.0000 | |
| 87 | T | H | -0.7861 | |
| 88 | A | H | 0.0000 | |
| 89 | V | H | 0.4476 | |
| 90 | Y | H | 0.0000 | |
| 91 | Y | H | 0.0000 | |
| 92 | C | H | 0.0000 | |
| 93 | V | H | 0.0000 | |
| 94 | R | H | -0.1543 | |
| 95 | R | H | -0.0901 | |
| 96 | Q | H | -0.2309 | |
| 97 | R | H | -1.2081 | |
| 98 | F | H | 0.8572 | |
| 99 | P | H | 0.3764 | |
| 100 | Y | H | 0.3595 | |
| 100A | Y | H | 0.0000 | |
| 100B | F | H | 0.0000 | |
| 101 | D | H | 0.0000 | |
| 102 | Y | H | 0.2600 | |
| 103 | W | H | 0.0000 | |
| 104 | G | H | 0.0000 | |
| 105 | Q | H | -1.2411 | |
| 106 | G | H | -0.6856 | |
| 107 | T | H | 0.0000 | |
| 108 | L | H | 0.6311 | |
| 109 | V | H | 0.0000 | |
| 110 | T | H | -0.3345 | |
| 111 | V | H | 0.0000 | |
| 112 | S | H | -0.8702 |