Project name: 5euk:A
Status: done
submitted: 2019-03-20 20:25:53, status changed: 2019-03-20 20:39:00
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6611
-
Maximal score value
-
1.7828
-
Average score
-
-0.8348
-
Total score value
-
-176.9877
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.3986 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7432 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.2011 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
0.0972 |
|
| 8 |
P |
A |
0.7740 |
|
| 9 |
V |
A |
1.7828 |
|
| 10 |
I |
A |
1.0941 |
|
| 11 |
L |
A |
0.3564 |
|
| 12 |
S |
A |
-0.5811 |
|
| 13 |
V |
A |
-1.2855 |
|
| 14 |
S |
A |
-1.8965 |
|
| 15 |
P |
A |
-2.1074 |
|
| 16 |
G |
A |
-2.1765 |
|
| 17 |
E |
A |
-3.0113 |
|
| 18 |
R |
A |
-3.2802 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.7184 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.7387 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.3946 |
|
| 25 |
A |
A |
-1.3484 |
|
| 26 |
S |
A |
-1.0584 |
|
| 27 |
Q |
A |
-1.7664 |
|
| 28 |
S |
A |
-1.5446 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.0509 |
|
| 31 |
T |
A |
-0.7167 |
|
| 32 |
N |
A |
-0.9707 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.1237 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.5108 |
|
| 39 |
R |
A |
-2.0676 |
|
| 40 |
T |
A |
-1.8343 |
|
| 41 |
N |
A |
-1.9732 |
|
| 42 |
G |
A |
-1.5602 |
|
| 43 |
S |
A |
-1.0865 |
|
| 44 |
P |
A |
-1.0120 |
|
| 45 |
R |
A |
-0.8801 |
|
| 46 |
L |
A |
-0.1279 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.7565 |
|
| 50 |
Y |
A |
-0.1717 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1158 |
|
| 53 |
E |
A |
-1.9128 |
|
| 54 |
S |
A |
-1.0827 |
|
| 55 |
I |
A |
-0.4709 |
|
| 56 |
S |
A |
-0.4217 |
|
| 57 |
G |
A |
-0.3840 |
|
| 58 |
I |
A |
-0.1412 |
|
| 59 |
P |
A |
-0.2801 |
|
| 60 |
S |
A |
-0.5481 |
|
| 61 |
R |
A |
-1.1167 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.8937 |
|
| 64 |
G |
A |
-0.6613 |
|
| 65 |
S |
A |
-0.7384 |
|
| 66 |
G |
A |
-0.9929 |
|
| 67 |
S |
A |
-1.0225 |
|
| 68 |
G |
A |
-1.3176 |
|
| 69 |
T |
A |
-1.8878 |
|
| 70 |
D |
A |
-2.3670 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.8112 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.8732 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.4328 |
|
| 77 |
S |
A |
-2.3655 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.5945 |
|
| 80 |
S |
A |
-2.2874 |
|
| 81 |
E |
A |
-2.1552 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
-1.6951 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.9181 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.1424 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.2920 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.3454 |
|
| 92 |
N |
A |
-1.8005 |
|
| 93 |
N |
A |
-1.2121 |
|
| 94 |
W |
A |
0.1081 |
|
| 95 |
P |
A |
-0.2475 |
|
| 96 |
T |
A |
-0.4296 |
|
| 97 |
T |
A |
0.2968 |
|
| 98 |
F |
A |
1.4203 |
|
| 99 |
G |
A |
0.6592 |
|
| 100 |
A |
A |
0.5648 |
|
| 101 |
G |
A |
0.2496 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.8344 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.4703 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.8092 |
|
| 108 |
R |
A |
-1.3050 |
|
| 109 |
T |
A |
-0.1553 |
|
| 110 |
V |
A |
0.3816 |
|
| 111 |
A |
A |
0.1072 |
|
| 112 |
A |
A |
-0.1678 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.0914 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.3534 |
|
| 117 |
I |
A |
1.2841 |
|
| 118 |
F |
A |
1.4789 |
|
| 119 |
P |
A |
-0.1017 |
|
| 120 |
P |
A |
-0.7284 |
|
| 121 |
S |
A |
-1.8316 |
|
| 122 |
D |
A |
-3.2184 |
|
| 123 |
E |
A |
-3.3840 |
|
| 124 |
Q |
A |
-2.4521 |
|
| 125 |
L |
A |
-2.5218 |
|
| 126 |
K |
A |
-2.9602 |
|
| 127 |
S |
A |
-1.8207 |
|
| 128 |
G |
A |
-1.1700 |
|
| 129 |
T |
A |
-1.0796 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0586 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7447 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.5585 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.5606 |
|
| 138 |
N |
A |
-1.2651 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
-1.1701 |
|
| 141 |
P |
A |
-1.7567 |
|
| 142 |
R |
A |
-2.9316 |
|
| 143 |
E |
A |
-3.2087 |
|
| 144 |
A |
A |
-2.2455 |
|
| 145 |
K |
A |
-2.0061 |
|
| 146 |
V |
A |
-0.9159 |
|
| 147 |
Q |
A |
-0.5360 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.7308 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.9837 |
|
| 152 |
N |
A |
-1.4820 |
|
| 153 |
A |
A |
-0.4408 |
|
| 154 |
L |
A |
0.4775 |
|
| 155 |
Q |
A |
-0.3091 |
|
| 156 |
S |
A |
-0.4356 |
|
| 157 |
G |
A |
-1.0086 |
|
| 158 |
N |
A |
-0.9861 |
|
| 159 |
S |
A |
-1.3563 |
|
| 160 |
Q |
A |
-2.2200 |
|
| 161 |
E |
A |
-2.1817 |
|
| 162 |
S |
A |
-1.2912 |
|
| 163 |
V |
A |
-0.8403 |
|
| 164 |
T |
A |
-1.2924 |
|
| 165 |
E |
A |
-2.5074 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.2288 |
|
| 168 |
S |
A |
-2.3175 |
|
| 169 |
K |
A |
-2.5984 |
|
| 170 |
D |
A |
-1.8242 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-1.0196 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4203 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.5475 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.4969 |
|
| 181 |
L |
A |
-0.6824 |
|
| 182 |
S |
A |
-1.0298 |
|
| 183 |
K |
A |
-2.0453 |
|
| 184 |
A |
A |
-1.8872 |
|
| 185 |
D |
A |
-2.5430 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.6611 |
|
| 188 |
K |
A |
-3.6293 |
|
| 189 |
H |
A |
-3.2109 |
|
| 190 |
K |
A |
-3.2155 |
|
| 191 |
V |
A |
-1.6290 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
-0.8572 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.7395 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.1168 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.6980 |
|
| 200 |
G |
A |
-0.3775 |
|
| 201 |
L |
A |
-0.1942 |
|
| 202 |
S |
A |
-0.4383 |
|
| 203 |
S |
A |
-0.4267 |
|
| 204 |
P |
A |
-0.6006 |
|
| 205 |
V |
A |
0.0107 |
|
| 206 |
T |
A |
-0.2668 |
|
| 207 |
K |
A |
-0.2655 |
|
| 208 |
S |
A |
-0.4045 |
|
| 209 |
F |
A |
-0.8273 |
|
| 210 |
N |
A |
-2.2114 |
|
| 211 |
R |
A |
-2.5557 |
|
| 212 |
G |
A |
-1.4191 |
|