Project name: 4zyp:J

Chain sequence(s)	J: QVTLRESGPALVKPTQTLTLTCTFSGFSLSTAGMSVGWIRQPPGKALEWLADIWWDDKKHYNPSLKDRLTISKDTSKNQVVLKVTNMDPADTATYYCARDMIFNFYFDVWGQGTTVTVSSASTKGPSVFPLAPSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3976
• Maximal score value: 2.6854
• Average score: -0.5289
• Total score value: -112.6493

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	J	-1.2561
2	V	J	-0.7283
3	T	J	-0.7516
4	L	J	0.0000
5	R	J	-1.6754
6	E	J	0.0000
7	S	J	-0.5123
8	G	J	-0.2170
9	P	J	0.0055
10	A	J	0.3305
11	L	J	0.4295
12	V	J	0.0000
13	K	J	-2.2313
14	P	J	-1.9791
15	T	J	-2.0546
16	Q	J	-2.2930
17	T	J	-1.5277
18	L	J	0.0000
19	T	J	-0.6137
20	L	J	0.0000
21	T	J	-0.4523
22	C	J	0.0000
23	T	J	-1.0888
24	F	J	0.0000
25	S	J	-1.0186
26	G	J	-0.8624
27	F	J	-0.3590
28	S	J	-0.4343
29	L	J	0.0000
30	S	J	-0.7157
31	T	J	-0.1998
32	A	J	0.0120
33	G	J	0.0000
34	M	J	0.5957
35	S	J	0.0000
35A	V	J	0.0000
35B	G	J	0.0000
36	W	J	0.0000
37	I	J	0.0000
38	R	J	0.0000
39	Q	J	-0.7528
40	P	J	0.0000
41	P	J	-1.0220
42	G	J	-1.3710
43	K	J	-1.9671
44	A	J	-0.6858
45	L	J	0.1286
46	E	J	-0.4919
47	W	J	0.1356
48	L	J	0.0000
49	A	J	0.0000
50	D	J	0.0000
51	I	J	0.0000
52	W	J	0.0000
53	W	J	-1.4599
54	D	J	-2.9441
55	D	J	-3.3976
56	K	J	-3.3910
57	K	J	-2.3772
58	H	J	-1.2684
59	Y	J	-0.7188
60	N	J	-0.8765
61	P	J	-1.1429
62	S	J	-0.8401
63	L	J	-1.0391
64	K	J	-2.1877
65	D	J	-2.5320
66	R	J	-2.0215
67	L	J	0.0000
68	T	J	-0.9718
69	I	J	0.0000
70	S	J	-1.1411
71	K	J	-1.3581
72	D	J	-1.7202
73	T	J	-1.3513
74	S	J	-1.5455
75	K	J	-2.3561
76	N	J	-1.7178
77	Q	J	-1.5003
78	V	J	0.0000
79	V	J	-0.2904
80	L	J	0.0000
81	K	J	-1.1091
82	V	J	0.0000
82A	T	J	-1.8485
82B	N	J	-2.2912
82C	M	J	0.0000
83	D	J	-2.2406
84	P	J	-1.1860
85	A	J	-0.5902
86	D	J	0.0000
87	T	J	-0.3387
88	A	J	0.0000
89	T	J	-0.2065
90	Y	J	0.0000
91	Y	J	-0.0976
92	C	J	0.0000
93	A	J	0.0000
94	R	J	0.0000
95	D	J	0.0000
96	M	J	1.7835
97	I	J	2.6232
98	F	J	2.6296
99	N	J	1.3419
100	F	J	2.6854
100A	Y	J	2.0638
100B	F	J	0.5360
101	D	J	-0.7973
102	V	J	-0.2882
103	W	J	-0.1850
104	G	J	0.0000
105	Q	J	-1.3994
106	G	J	-0.9200
107	T	J	-0.5797
108	T	J	-0.0374
109	V	J	0.0000
110	T	J	-0.2513
111	V	J	0.0000
112	S	J	-0.8303
113	S	J	-0.7175
114	A	J	-0.5499
115	S	J	-0.6336
116	T	J	-0.9670
117	K	J	-1.7215
118	G	J	-1.7259
119	P	J	0.0000
120	S	J	-0.0739
121	V	J	0.0000
122	F	J	1.8514
123	P	J	0.6172
124	L	J	0.9241
125	A	J	-0.1566
126	P	J	0.0000
127	S	J	-0.3475
135	T	J	-0.2471
136	A	J	-0.1817
137	A	J	0.1114
138	L	J	0.0000
139	G	J	0.0000
140	C	J	0.0000
141	L	J	0.9803
142	V	J	0.0000
143	K	J	-0.4700
144	D	J	-1.1340
145	Y	J	0.0000
146	F	J	0.0000
147	P	J	-1.0179
148	E	J	-1.3101
149	P	J	-1.2411
150	V	J	0.0000
151	T	J	-0.6971
152	V	J	-0.2416
153	S	J	-0.5188
154	W	J	0.0000
155	N	J	-0.9540
156	S	J	-0.7960
157	G	J	-0.6130
158	A	J	-0.3331
159	L	J	-0.1162
160	T	J	-0.3807
161	S	J	-0.4116
162	G	J	-0.4933
163	V	J	-0.0464
164	H	J	-0.4639
165	T	J	0.2398
166	F	J	1.1690
167	P	J	0.7467
168	A	J	1.1991
169	V	J	2.5559
170	L	J	1.9740
171	Q	J	0.5023
172	S	J	-0.1467
173	S	J	-0.3127
174	G	J	-0.1637
175	L	J	-0.0499
176	Y	J	0.6233
177	S	J	0.0000
178	L	J	0.0000
179	S	J	0.8065
180	S	J	0.0000
181	V	J	0.5010
182	V	J	0.0000
183	T	J	-0.2177
184	V	J	0.0000
185	P	J	-0.4924
186	S	J	-0.4649
187	S	J	-0.5289
188	S	J	-0.5632
189	L	J	-0.7351
190	G	J	-1.0232
191	T	J	-0.6683
192	Q	J	-1.1229
193	T	J	-1.1133
194	Y	J	0.0000
195	I	J	-1.4335
196	C	J	0.0000
197	N	J	-1.8926
198	V	J	0.0000
199	N	J	-2.4123
200	H	J	0.0000
201	K	J	-3.0279
202	P	J	-1.8864
203	S	J	-2.0267
204	N	J	-2.7373
205	T	J	-2.4519
206	K	J	-3.0036
207	V	J	-2.0566
208	D	J	-2.9277
209	K	J	-2.3169
210	K	J	-2.7199
211	V	J	0.0000
212	E	J	-2.1199
213	P	J	-0.9670