| Chain sequence(s) |
H: QVQLQESGPGLVKPSETLSLTCTVSGYSITGGYLWNWIRQPPGKGLEWIGYISYDGTNNYKPSLKDRVTISRDTSKNQFSLKLSSVTAADTAVYYCARYGRVFFDYWGQGTLVTVS L: DIVMTQSPLSLPVTPGEPASISCRSSQSIVHSNGNTYLQWYLQKPGQSPQLLIYKVSNRLYGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCFQGSHVPWTFGQGTKVEI |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | D | L | -1.2601 | |
| 2 | I | L | -0.1134 | |
| 3 | V | L | 0.3891 | |
| 4 | M | L | 0.0000 | |
| 5 | T | L | -0.6026 | |
| 6 | Q | L | 0.0000 | |
| 7 | S | L | -0.2988 | |
| 8 | P | L | 0.0584 | |
| 9 | L | L | 0.5958 | |
| 10 | S | L | -0.1670 | |
| 11 | L | L | -0.0358 | |
| 12 | P | L | -0.3046 | |
| 13 | V | L | 0.0000 | |
| 14 | T | L | -0.6503 | |
| 15 | P | L | -1.0853 | |
| 16 | G | L | -1.7377 | |
| 17 | E | L | -2.1674 | |
| 18 | P | L | -2.1789 | |
| 19 | A | L | -1.2826 | |
| 20 | S | L | -0.7107 | |
| 21 | I | L | 0.0000 | |
| 22 | S | L | -0.9837 | |
| 23 | C | L | 0.0000 | |
| 24 | R | L | -2.4208 | |
| 25 | S | L | 0.0000 | |
| 26 | S | L | -1.0557 | |
| 27 | Q | L | -1.4225 | |
| 28 | S | L | -0.9175 | |
| 29 | I | L | 0.0000 | |
| 30 | V | L | -0.0741 | |
| 30A | H | L | -0.9482 | |
| 30B | S | L | -1.1107 | |
| 30C | N | L | -1.8776 | |
| 30D | G | L | -1.5123 | |
| 30E | N | L | -1.6105 | |
| 31 | T | L | -0.6648 | |
| 32 | Y | L | -0.2495 | |
| 33 | L | L | 0.0000 | |
| 34 | Q | L | 0.0000 | |
| 35 | W | L | 0.0000 | |
| 36 | Y | L | 0.0000 | |
| 37 | L | L | 0.0000 | |
| 38 | Q | L | -1.1954 | |
| 39 | K | L | -1.7531 | |
| 40 | P | L | -1.2835 | |
| 41 | G | L | -1.3784 | |
| 42 | Q | L | -2.1527 | |
| 43 | S | L | -1.5310 | |
| 44 | P | L | 0.0000 | |
| 45 | Q | L | -1.4795 | |
| 46 | L | L | 0.0000 | |
| 47 | L | L | 0.0000 | |
| 48 | I | L | 0.0000 | |
| 49 | Y | L | -0.4750 | |
| 50 | K | L | -1.0023 | |
| 51 | V | L | -0.7440 | |
| 52 | S | L | -0.9480 | |
| 53 | N | L | -1.2027 | |
| 54 | R | L | -1.4045 | |
| 55 | L | L | -0.0336 | |
| 56 | Y | L | 0.9092 | |
| 57 | G | L | -0.1223 | |
| 58 | V | L | -0.7117 | |
| 59 | P | L | -1.3378 | |
| 60 | D | L | -2.5024 | |
| 61 | R | L | -2.6023 | |
| 62 | F | L | 0.0000 | |
| 63 | S | L | -1.5352 | |
| 64 | G | L | 0.0000 | |
| 65 | S | L | -0.9177 | |
| 66 | G | L | -1.0479 | |
| 67 | S | L | -0.8387 | |
| 68 | G | L | -0.7750 | |
| 69 | T | L | -1.5336 | |
| 70 | D | L | -2.1744 | |
| 71 | F | L | 0.0000 | |
| 72 | T | L | -1.0841 | |
| 73 | L | L | 0.0000 | |
| 74 | K | L | -1.7474 | |
| 75 | I | L | 0.0000 | |
| 76 | S | L | -2.4959 | |
| 77 | R | L | -3.1510 | |
| 78 | V | L | 0.0000 | |
| 79 | E | L | -2.2175 | |
| 80 | A | L | -1.0537 | |
| 81 | E | L | -2.0658 | |
| 82 | D | L | 0.0000 | |
| 83 | V | L | -0.8091 | |
| 84 | G | L | 0.0000 | |
| 85 | V | L | -0.3473 | |
| 86 | Y | L | 0.0000 | |
| 87 | Y | L | 0.0000 | |
| 88 | C | L | 0.0000 | |
| 89 | F | L | 0.0000 | |
| 90 | Q | L | 0.0000 | |
| 91 | G | L | -0.0051 | |
| 92 | S | L | 0.0000 | |
| 93 | H | L | 0.1354 | |
| 94 | V | L | 1.1245 | |
| 95 | P | L | 0.2637 | |
| 96 | W | L | 0.0000 | |
| 97 | T | L | 0.0228 | |
| 98 | F | L | 0.0000 | |
| 99 | G | L | -0.4003 | |
| 100 | Q | L | -0.9286 | |
| 101 | G | L | 0.0000 | |
| 102 | T | L | 0.0000 | |
| 103 | K | L | -0.9375 | |
| 104 | V | L | 0.0000 | |
| 105 | E | L | -0.8660 | |
| 106 | I | L | 0.7722 | |
| 1 | Q | H | -1.3052 | |
| 2 | V | H | -0.7112 | |
| 3 | Q | H | -1.3678 | |
| 4 | L | H | 0.0000 | |
| 5 | Q | H | -1.5889 | |
| 6 | E | H | 0.0000 | |
| 7 | S | H | -0.5524 | |
| 8 | G | H | -0.2893 | |
| 9 | P | H | 0.1433 | |
| 10 | G | H | 0.7972 | |
| 11 | L | H | 1.0934 | |
| 12 | V | H | 0.0000 | |
| 13 | K | H | -2.0695 | |
| 14 | P | H | -1.5271 | |
| 15 | S | H | -1.6357 | |
| 16 | E | H | -2.3919 | |
| 17 | T | H | -1.5724 | |
| 18 | L | H | 0.0000 | |
| 19 | S | H | -0.8497 | |
| 20 | L | H | 0.0000 | |
| 21 | T | H | -0.7813 | |
| 22 | C | H | 0.0000 | |
| 23 | T | H | -1.0814 | |
| 24 | V | H | 0.0000 | |
| 25 | S | H | -0.7670 | |
| 26 | G | H | -0.6198 | |
| 27 | Y | H | 0.2414 | |
| 28 | S | H | -0.0625 | |
| 29 | I | H | 0.0000 | |
| 30 | T | H | -0.5296 | |
| 31 | G | H | -0.3113 | |
| 31A | G | H | -0.1540 | |
| 32 | Y | H | 0.0094 | |
| 33 | L | H | -0.2755 | |
| 34 | W | H | 0.0000 | |
| 35 | N | H | 0.0000 | |
| 36 | W | H | 0.0000 | |
| 37 | I | H | 0.0000 | |
| 38 | R | H | 0.0000 | |
| 39 | Q | H | -0.5972 | |
| 40 | P | H | -0.7302 | |
| 41 | P | H | -0.8482 | |
| 42 | G | H | -1.4806 | |
| 43 | K | H | -2.3037 | |
| 44 | G | H | -1.4482 | |
| 45 | L | H | 0.0000 | |
| 46 | E | H | -0.7169 | |
| 47 | W | H | 0.0000 | |
| 48 | I | H | 0.0000 | |
| 49 | G | H | 0.0000 | |
| 50 | Y | H | 0.0000 | |
| 51 | I | H | 0.0000 | |
| 52 | S | H | 0.0000 | |
| 53 | Y | H | -0.4833 | |
| 54 | D | H | -1.7799 | |
| 55 | G | H | -1.3872 | |
| 56 | T | H | -0.9723 | |
| 57 | N | H | -0.9809 | |
| 58 | N | H | -0.8140 | |
| 59 | Y | H | -0.9144 | |
| 60 | K | H | -1.0976 | |
| 61 | P | H | -1.3478 | |
| 62 | S | H | -1.4075 | |
| 63 | L | H | 0.0000 | |
| 64 | K | H | -2.9154 | |
| 65 | D | H | -2.9195 | |
| 66 | R | H | -2.0755 | |
| 67 | V | H | 0.0000 | |
| 68 | T | H | -1.1872 | |
| 69 | I | H | 0.0000 | |
| 70 | S | H | -1.0695 | |
| 71 | R | H | -1.9876 | |
| 72 | D | H | -1.8814 | |
| 73 | T | H | -1.5218 | |
| 74 | S | H | -1.4834 | |
| 75 | K | H | -2.3373 | |
| 76 | N | H | -1.6023 | |
| 77 | Q | H | -1.6099 | |
| 78 | F | H | 0.0000 | |
| 79 | S | H | -0.8110 | |
| 80 | L | H | 0.0000 | |
| 81 | K | H | -1.1870 | |
| 82 | L | H | 0.0000 | |
| 82A | S | H | -1.3883 | |
| 82B | S | H | -1.4459 | |
| 82C | V | H | 0.0000 | |
| 83 | T | H | -0.7272 | |
| 84 | A | H | -0.2491 | |
| 85 | A | H | 0.0417 | |
| 86 | D | H | 0.0000 | |
| 87 | T | H | 0.3918 | |
| 88 | A | H | 0.0000 | |
| 89 | V | H | 0.6795 | |
| 90 | Y | H | 0.0000 | |
| 91 | Y | H | 0.0000 | |
| 92 | C | H | 0.0000 | |
| 93 | A | H | 0.0000 | |
| 94 | R | H | -0.3695 | |
| 95 | Y | H | -0.3827 | |
| 96 | G | H | 0.0000 | |
| 97 | R | H | -1.6656 | |
| 98 | V | H | 0.0000 | |
| 99 | F | H | 0.0000 | |
| 100 | F | H | 0.0000 | |
| 101 | D | H | -0.5550 | |
| 102 | Y | H | -0.3440 | |
| 103 | W | H | 0.0000 | |
| 104 | G | H | 0.0000 | |
| 105 | Q | H | -1.5326 | |
| 106 | G | H | -0.5865 | |
| 107 | T | H | 0.2354 | |
| 108 | L | H | 1.5513 | |
| 109 | V | H | 0.0000 | |
| 110 | T | H | 0.5383 | |
| 111 | V | H | 0.0000 | |
| 112 | S | H | -0.5068 |