Project name: 5y9k:L
Status: done
submitted: 2019-03-21 13:08:13, status changed: 2019-03-21 13:17:47
Settings
|
Chain sequence(s)
|
L: ELTQDPAVSVALGQTVRVTCQGDSLRSYYASWYQQKPGQAPVLVIYGKNNRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCSSRDSSGNHWVFGGGTELTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.1774
-
Maximal score value
-
1.6952
-
Average score
-
-0.7636
-
Total score value
-
-159.5979
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 3 |
E |
L |
-2.0375 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.9786 |
|
| 6 |
Q |
L |
-1.2186 |
|
| 7 |
D |
L |
-2.0122 |
|
| 8 |
P |
L |
-1.5931 |
|
| 9 |
A |
L |
-1.2443 |
|
| 10 |
V |
L |
-0.8409 |
|
| 11 |
S |
L |
-0.2209 |
|
| 12 |
V |
L |
0.0000 |
|
| 13 |
A |
L |
0.0630 |
|
| 14 |
L |
L |
0.2640 |
|
| 15 |
G |
L |
-0.6251 |
|
| 16 |
Q |
L |
-1.0900 |
|
| 17 |
T |
L |
-1.1339 |
|
| 18 |
V |
L |
0.0000 |
|
| 19 |
R |
L |
-1.8574 |
|
| 20 |
V |
L |
0.0000 |
|
| 21 |
T |
L |
-0.9824 |
|
| 22 |
C |
L |
0.0000 |
|
| 23 |
Q |
L |
-1.9879 |
|
| 24 |
G |
L |
0.0000 |
|
| 25 |
D |
L |
-3.1178 |
|
| 26 |
S |
L |
0.0000 |
|
| 27 |
L |
L |
0.0000 |
|
| 28 |
R |
L |
-2.6006 |
|
| 29 |
S |
L |
-1.2908 |
|
| 30 |
Y |
L |
-0.0836 |
|
| 31 |
Y |
L |
0.5403 |
|
| 32 |
A |
L |
0.0000 |
|
| 33 |
S |
L |
0.0000 |
|
| 34 |
W |
L |
0.0000 |
|
| 35 |
Y |
L |
0.8891 |
|
| 36 |
Q |
L |
-0.2319 |
|
| 37 |
Q |
L |
-1.0336 |
|
| 38 |
K |
L |
-1.8355 |
|
| 39 |
P |
L |
-1.3845 |
|
| 40 |
G |
L |
-1.3996 |
|
| 41 |
Q |
L |
-1.6009 |
|
| 42 |
A |
L |
-0.5518 |
|
| 43 |
P |
L |
-0.0355 |
|
| 44 |
V |
L |
1.2187 |
|
| 45 |
L |
L |
1.0750 |
|
| 46 |
V |
L |
0.0000 |
|
| 47 |
I |
L |
0.0000 |
|
| 48 |
Y |
L |
-0.2321 |
|
| 49 |
G |
L |
-0.7927 |
|
| 50 |
K |
L |
-2.2012 |
|
| 51 |
N |
L |
-2.1738 |
|
| 52 |
N |
L |
-2.1475 |
|
| 53 |
R |
L |
-1.9829 |
|
| 54 |
P |
L |
-0.5095 |
|
| 55 |
S |
L |
-0.6683 |
|
| 56 |
G |
L |
-0.8824 |
|
| 57 |
I |
L |
-0.7246 |
|
| 58 |
P |
L |
-1.3312 |
|
| 59 |
D |
L |
-2.2817 |
|
| 60 |
R |
L |
-1.3242 |
|
| 61 |
F |
L |
0.0000 |
|
| 62 |
S |
L |
-1.5401 |
|
| 63 |
G |
L |
-1.1993 |
|
| 64 |
S |
L |
-0.8505 |
|
| 65 |
S |
L |
-0.9638 |
|
| 66 |
S |
L |
-0.8813 |
|
| 67 |
G |
L |
-1.7048 |
|
| 68 |
N |
L |
-2.0052 |
|
| 69 |
T |
L |
-1.2506 |
|
| 70 |
A |
L |
0.0000 |
|
| 71 |
S |
L |
-0.8557 |
|
| 72 |
L |
L |
0.0000 |
|
| 73 |
T |
L |
-0.9398 |
|
| 74 |
I |
L |
0.0000 |
|
| 75 |
T |
L |
-1.1267 |
|
| 76 |
G |
L |
-0.7390 |
|
| 77 |
A |
L |
0.0000 |
|
| 78 |
Q |
L |
-1.1232 |
|
| 79 |
A |
L |
-1.0999 |
|
| 80 |
E |
L |
-2.3036 |
|
| 81 |
D |
L |
0.0000 |
|
| 82 |
E |
L |
0.0000 |
|
| 83 |
A |
L |
0.0000 |
|
| 84 |
D |
L |
-1.6921 |
|
| 85 |
Y |
L |
0.0000 |
|
| 86 |
Y |
L |
0.2457 |
|
| 87 |
C |
L |
0.0000 |
|
| 88 |
S |
L |
0.0000 |
|
| 89 |
S |
L |
0.0000 |
|
| 90 |
R |
L |
-0.4173 |
|
| 91 |
D |
L |
-1.4033 |
|
| 92 |
S |
L |
-1.6221 |
|
| 93 |
S |
L |
-1.0196 |
|
| 94 |
G |
L |
-1.1702 |
|
| 95 |
N |
L |
-1.7485 |
|
| 96 |
H |
L |
-1.1528 |
|
| 97 |
W |
L |
0.6383 |
|
| 98 |
V |
L |
0.6355 |
|
| 99 |
F |
L |
1.5981 |
|
| 100 |
G |
L |
0.0000 |
|
| 101 |
G |
L |
-0.7677 |
|
| 102 |
G |
L |
-0.8984 |
|
| 103 |
T |
L |
0.0000 |
|
| 104 |
E |
L |
-2.4408 |
|
| 105 |
L |
L |
0.0000 |
|
| 106 |
T |
L |
-0.2757 |
|
| 107 |
V |
L |
0.0000 |
|
| 108 |
L |
L |
0.5384 |
|
| 109 |
G |
L |
-0.1392 |
|
| 110 |
Q |
L |
0.0000 |
|
| 111 |
P |
L |
-1.0815 |
|
| 112 |
K |
L |
-2.0489 |
|
| 113 |
A |
L |
-1.2238 |
|
| 114 |
A |
L |
-0.7752 |
|
| 115 |
P |
L |
0.0000 |
|
| 116 |
S |
L |
-0.2940 |
|
| 117 |
V |
L |
0.0000 |
|
| 118 |
T |
L |
0.2942 |
|
| 119 |
L |
L |
0.7864 |
|
| 120 |
F |
L |
1.6952 |
|
| 121 |
P |
L |
0.6708 |
|
| 122 |
P |
L |
0.0000 |
|
| 123 |
S |
L |
-1.0689 |
|
| 124 |
S |
L |
-1.8316 |
|
| 125 |
E |
L |
-2.8421 |
|
| 126 |
E |
L |
-2.4601 |
|
| 127 |
L |
L |
-2.3959 |
|
| 128 |
Q |
L |
-2.6078 |
|
| 129 |
A |
L |
-2.1788 |
|
| 130 |
N |
L |
-2.9452 |
|
| 131 |
K |
L |
-3.0595 |
|
| 132 |
A |
L |
0.0000 |
|
| 133 |
T |
L |
-0.0761 |
|
| 134 |
L |
L |
0.0000 |
|
| 135 |
V |
L |
1.1690 |
|
| 136 |
C |
L |
0.0000 |
|
| 137 |
L |
L |
1.0314 |
|
| 138 |
I |
L |
0.0000 |
|
| 139 |
S |
L |
-0.4330 |
|
| 140 |
D |
L |
-1.1591 |
|
| 141 |
F |
L |
0.0000 |
|
| 142 |
Y |
L |
-0.8747 |
|
| 143 |
P |
L |
-0.7988 |
|
| 144 |
G |
L |
-0.4304 |
|
| 145 |
A |
L |
-0.2225 |
|
| 146 |
V |
L |
-0.1495 |
|
| 147 |
T |
L |
-0.1320 |
|
| 148 |
V |
L |
-0.0967 |
|
| 149 |
A |
L |
-0.5806 |
|
| 150 |
W |
L |
0.0000 |
|
| 151 |
K |
L |
-0.9772 |
|
| 152 |
A |
L |
0.0000 |
|
| 153 |
D |
L |
-1.1933 |
|
| 154 |
S |
L |
-0.8175 |
|
| 155 |
S |
L |
-0.7170 |
|
| 156 |
P |
L |
-0.8501 |
|
| 157 |
V |
L |
-0.8076 |
|
| 158 |
K |
L |
-1.8052 |
|
| 159 |
A |
L |
-1.0081 |
|
| 160 |
G |
L |
-0.8631 |
|
| 161 |
V |
L |
-0.7523 |
|
| 162 |
E |
L |
-1.6545 |
|
| 163 |
T |
L |
-0.6471 |
|
| 164 |
T |
L |
-0.4402 |
|
| 165 |
T |
L |
-0.1269 |
|
| 166 |
P |
L |
-0.2663 |
|
| 167 |
S |
L |
-0.4878 |
|
| 168 |
K |
L |
-0.9854 |
|
| 169 |
Q |
L |
-1.1693 |
|
| 170 |
S |
L |
-1.6355 |
|
| 171 |
N |
L |
-1.8359 |
|
| 172 |
N |
L |
0.0000 |
|
| 173 |
K |
L |
-1.1739 |
|
| 174 |
Y |
L |
-0.5855 |
|
| 175 |
A |
L |
-0.2834 |
|
| 176 |
A |
L |
0.0000 |
|
| 177 |
S |
L |
0.1110 |
|
| 178 |
S |
L |
0.0000 |
|
| 179 |
Y |
L |
0.4596 |
|
| 180 |
L |
L |
0.0000 |
|
| 181 |
S |
L |
-0.6262 |
|
| 182 |
L |
L |
-1.1511 |
|
| 183 |
T |
L |
-1.8925 |
|
| 184 |
P |
L |
-2.5771 |
|
| 185 |
E |
L |
-3.1774 |
|
| 186 |
Q |
L |
-2.3129 |
|
| 187 |
W |
L |
0.0000 |
|
| 188 |
K |
L |
-3.0836 |
|
| 189 |
S |
L |
-2.3995 |
|
| 190 |
H |
L |
-2.3165 |
|
| 191 |
R |
L |
-2.4466 |
|
| 192 |
S |
L |
-1.4507 |
|
| 193 |
Y |
L |
0.0000 |
|
| 194 |
S |
L |
0.0000 |
|
| 195 |
C |
L |
0.0000 |
|
| 196 |
Q |
L |
-0.9928 |
|
| 197 |
V |
L |
0.0000 |
|
| 198 |
T |
L |
-0.6675 |
|
| 199 |
H |
L |
0.0000 |
|
| 200 |
E |
L |
-2.2498 |
|
| 201 |
G |
L |
-1.4127 |
|
| 202 |
S |
L |
-0.8696 |
|
| 203 |
T |
L |
-0.8122 |
|
| 204 |
V |
L |
-0.6700 |
|
| 205 |
E |
L |
-1.7172 |
|
| 206 |
K |
L |
-1.2650 |
|
| 207 |
T |
L |
-0.5972 |
|
| 208 |
V |
L |
-0.0201 |
|
| 209 |
A |
L |
-0.7246 |
|
| 210 |
P |
L |
-1.0123 |
|
| 211 |
T |
L |
-0.6545 |
|