Project name: 6azl:B
Status: done
submitted: 2019-03-20 16:18:59, status changed: 2019-03-20 17:33:30
Settings
|
Chain sequence(s)
|
B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8687
-
Maximal score value
-
2.3596
-
Average score
-
-0.537
-
Total score value
-
-118.142
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
B |
-1.4178 |
|
| 2 |
V |
B |
-0.7477 |
|
| 3 |
Q |
B |
-1.4327 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
K |
B |
-2.1673 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-0.8432 |
|
| 8 |
G |
B |
-1.2147 |
|
| 9 |
P |
B |
-0.5436 |
|
| 10 |
G |
B |
-0.4773 |
|
| 11 |
L |
B |
-0.1145 |
|
| 12 |
V |
B |
0.0000 |
|
| 13 |
Q |
B |
-1.7469 |
|
| 14 |
P |
B |
-1.7394 |
|
| 15 |
S |
B |
-1.6655 |
|
| 16 |
Q |
B |
-2.0102 |
|
| 17 |
S |
B |
-1.9245 |
|
| 18 |
L |
B |
0.0000 |
|
| 19 |
S |
B |
-0.9415 |
|
| 20 |
I |
B |
0.0000 |
|
| 21 |
T |
B |
-0.5917 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
T |
B |
-1.1161 |
|
| 24 |
V |
B |
0.0000 |
|
| 25 |
S |
B |
-1.1889 |
|
| 26 |
G |
B |
-0.9410 |
|
| 27 |
F |
B |
-0.4870 |
|
| 28 |
S |
B |
-0.8645 |
|
| 29 |
L |
B |
0.0000 |
|
| 30 |
T |
B |
-0.9203 |
|
| 31 |
N |
B |
-0.8901 |
|
| 32 |
Y |
B |
0.3739 |
|
| 33 |
G |
B |
0.0000 |
|
| 34 |
V |
B |
0.0000 |
|
| 35 |
H |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.2182 |
|
| 40 |
S |
B |
-0.9082 |
|
| 41 |
P |
B |
-1.0964 |
|
| 42 |
G |
B |
-1.6390 |
|
| 43 |
K |
B |
-1.9818 |
|
| 44 |
G |
B |
-0.5914 |
|
| 45 |
L |
B |
0.8463 |
|
| 46 |
E |
B |
0.0000 |
|
| 47 |
W |
B |
0.4703 |
|
| 48 |
L |
B |
0.0000 |
|
| 49 |
G |
B |
0.0000 |
|
| 50 |
V |
B |
0.0000 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
W |
B |
-0.6095 |
|
| 53 |
S |
B |
-0.6939 |
|
| 54 |
G |
B |
-1.2400 |
|
| 55 |
G |
B |
-1.5402 |
|
| 56 |
N |
B |
-1.9059 |
|
| 57 |
T |
B |
-1.4183 |
|
| 58 |
D |
B |
-1.3326 |
|
| 59 |
Y |
B |
-0.6199 |
|
| 60 |
N |
B |
-0.6148 |
|
| 61 |
T |
B |
-0.5078 |
|
| 62 |
P |
B |
-0.4778 |
|
| 63 |
F |
B |
0.0000 |
|
| 64 |
T |
B |
-0.5944 |
|
| 65 |
S |
B |
-0.7169 |
|
| 66 |
R |
B |
-1.3552 |
|
| 67 |
L |
B |
0.0000 |
|
| 68 |
S |
B |
-1.3730 |
|
| 69 |
I |
B |
0.0000 |
|
| 70 |
N |
B |
-1.8466 |
|
| 71 |
K |
B |
-1.4757 |
|
| 72 |
D |
B |
-1.7856 |
|
| 73 |
N |
B |
-2.1853 |
|
| 74 |
S |
B |
-1.6684 |
|
| 75 |
K |
B |
-2.3682 |
|
| 76 |
S |
B |
-1.6165 |
|
| 77 |
Q |
B |
-1.5267 |
|
| 78 |
V |
B |
0.0000 |
|
| 79 |
F |
B |
-0.4258 |
|
| 80 |
F |
B |
0.0000 |
|
| 81 |
K |
B |
-2.2267 |
|
| 82 |
M |
B |
0.0000 |
|
| 83 |
N |
B |
-2.3899 |
|
| 84 |
S |
B |
-1.7438 |
|
| 85 |
L |
B |
0.0000 |
|
| 86 |
Q |
B |
-2.2586 |
|
| 87 |
S |
B |
-1.5666 |
|
| 88 |
N |
B |
-2.0640 |
|
| 89 |
D |
B |
0.0000 |
|
| 90 |
T |
B |
-0.6745 |
|
| 91 |
A |
B |
0.0000 |
|
| 92 |
I |
B |
0.5581 |
|
| 93 |
Y |
B |
0.0000 |
|
| 94 |
Y |
B |
0.0749 |
|
| 95 |
C |
B |
0.0000 |
|
| 96 |
A |
B |
0.0000 |
|
| 97 |
R |
B |
0.0000 |
|
| 98 |
A |
B |
0.0000 |
|
| 99 |
L |
B |
1.7149 |
|
| 100 |
T |
B |
1.3797 |
|
| 101 |
Y |
B |
1.9523 |
|
| 102 |
Y |
B |
1.8283 |
|
| 103 |
D |
B |
0.9530 |
|
| 104 |
Y |
B |
1.0662 |
|
| 105 |
E |
B |
0.1773 |
|
| 106 |
F |
B |
0.7070 |
|
| 107 |
A |
B |
0.8003 |
|
| 108 |
Y |
B |
0.6111 |
|
| 109 |
W |
B |
0.1275 |
|
| 110 |
G |
B |
0.0000 |
|
| 111 |
Q |
B |
-1.4713 |
|
| 112 |
G |
B |
-0.6378 |
|
| 113 |
T |
B |
0.0000 |
|
| 114 |
L |
B |
0.2225 |
|
| 115 |
V |
B |
0.0000 |
|
| 116 |
T |
B |
-0.3486 |
|
| 117 |
V |
B |
0.0000 |
|
| 118 |
S |
B |
-0.7454 |
|
| 119 |
A |
B |
-0.4025 |
|
| 120 |
A |
B |
-0.3582 |
|
| 121 |
S |
B |
-0.6213 |
|
| 122 |
T |
B |
-0.8652 |
|
| 123 |
K |
B |
-1.5453 |
|
| 124 |
G |
B |
-1.6081 |
|
| 125 |
P |
B |
0.0000 |
|
| 126 |
S |
B |
-0.2058 |
|
| 127 |
V |
B |
0.0000 |
|
| 128 |
F |
B |
1.0934 |
|
| 129 |
P |
B |
0.2370 |
|
| 130 |
L |
B |
0.5431 |
|
| 131 |
A |
B |
-0.9710 |
|
| 132 |
P |
B |
0.0000 |
|
| 133 |
S |
B |
-1.2987 |
|
| 134 |
S |
B |
-1.1391 |
|
| 135 |
K |
B |
-1.8786 |
|
| 136 |
S |
B |
-0.9680 |
|
| 137 |
T |
B |
-0.9954 |
|
| 138 |
S |
B |
-0.9422 |
|
| 139 |
G |
B |
-0.8529 |
|
| 140 |
G |
B |
-0.9182 |
|
| 141 |
T |
B |
-0.6530 |
|
| 142 |
A |
B |
0.0000 |
|
| 143 |
A |
B |
-0.1677 |
|
| 144 |
L |
B |
0.0000 |
|
| 145 |
G |
B |
0.0000 |
|
| 146 |
C |
B |
0.0000 |
|
| 147 |
L |
B |
0.7501 |
|
| 148 |
V |
B |
0.0000 |
|
| 149 |
K |
B |
-0.3246 |
|
| 150 |
D |
B |
-0.8880 |
|
| 151 |
Y |
B |
0.0000 |
|
| 152 |
F |
B |
0.0000 |
|
| 153 |
P |
B |
0.0000 |
|
| 154 |
E |
B |
-0.1440 |
|
| 155 |
P |
B |
-0.5441 |
|
| 156 |
V |
B |
-0.5554 |
|
| 157 |
T |
B |
-0.4958 |
|
| 158 |
V |
B |
-0.3707 |
|
| 159 |
S |
B |
-0.4261 |
|
| 160 |
W |
B |
0.0000 |
|
| 161 |
N |
B |
-0.9981 |
|
| 162 |
S |
B |
-0.7154 |
|
| 163 |
G |
B |
-0.5468 |
|
| 164 |
A |
B |
-0.2410 |
|
| 165 |
L |
B |
-0.0430 |
|
| 166 |
T |
B |
-0.2830 |
|
| 167 |
S |
B |
-0.3569 |
|
| 168 |
G |
B |
-0.4503 |
|
| 169 |
V |
B |
0.0453 |
|
| 170 |
H |
B |
-0.3053 |
|
| 171 |
T |
B |
0.2592 |
|
| 172 |
F |
B |
1.1028 |
|
| 173 |
P |
B |
0.6217 |
|
| 174 |
A |
B |
1.2596 |
|
| 175 |
V |
B |
2.3596 |
|
| 176 |
L |
B |
1.8713 |
|
| 177 |
Q |
B |
0.4913 |
|
| 178 |
S |
B |
-0.0048 |
|
| 179 |
S |
B |
-0.2998 |
|
| 180 |
G |
B |
0.1231 |
|
| 181 |
L |
B |
0.1034 |
|
| 182 |
Y |
B |
0.6520 |
|
| 183 |
S |
B |
0.0000 |
|
| 184 |
L |
B |
0.0000 |
|
| 185 |
S |
B |
0.7409 |
|
| 186 |
S |
B |
0.0000 |
|
| 187 |
V |
B |
0.5189 |
|
| 188 |
V |
B |
0.0000 |
|
| 189 |
T |
B |
-0.1979 |
|
| 190 |
V |
B |
0.0000 |
|
| 191 |
P |
B |
-0.5429 |
|
| 192 |
S |
B |
-0.5829 |
|
| 193 |
S |
B |
-0.5975 |
|
| 194 |
S |
B |
-0.6491 |
|
| 195 |
L |
B |
-0.8150 |
|
| 196 |
G |
B |
-0.9628 |
|
| 197 |
T |
B |
-0.7663 |
|
| 198 |
Q |
B |
-1.3203 |
|
| 199 |
T |
B |
-1.2676 |
|
| 200 |
Y |
B |
0.0000 |
|
| 201 |
I |
B |
-1.6544 |
|
| 202 |
C |
B |
0.0000 |
|
| 203 |
N |
B |
-1.4958 |
|
| 204 |
V |
B |
0.0000 |
|
| 205 |
N |
B |
-1.7196 |
|
| 206 |
H |
B |
0.0000 |
|
| 207 |
K |
B |
-2.7605 |
|
| 208 |
P |
B |
-1.6344 |
|
| 209 |
S |
B |
-1.8595 |
|
| 210 |
N |
B |
-2.5898 |
|
| 211 |
T |
B |
-2.0177 |
|
| 212 |
K |
B |
-2.5523 |
|
| 213 |
V |
B |
-1.4989 |
|
| 214 |
D |
B |
-2.6192 |
|
| 215 |
K |
B |
-2.2063 |
|
| 216 |
R |
B |
-2.7196 |
|
| 217 |
V |
B |
0.0000 |
|
| 218 |
E |
B |
-2.8687 |
|
| 219 |
P |
B |
-1.8462 |
|
| 220 |
K |
B |
-2.2012 |
|