Project name: 5icy:A
Status: done
submitted: 2019-03-20 20:30:02, status changed: 2019-03-20 20:36:10
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEEDIADYYCQQNNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADDYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5075
-
Maximal score value
-
1.8596
-
Average score
-
-0.8322
-
Total score value
-
-176.42
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.3904 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7578 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.3141 |
|
| 6 |
Q |
A |
0.0596 |
|
| 7 |
S |
A |
0.0865 |
|
| 8 |
P |
A |
0.8224 |
|
| 9 |
V |
A |
1.8596 |
|
| 10 |
I |
A |
1.2853 |
|
| 11 |
L |
A |
0.5652 |
|
| 12 |
S |
A |
-0.3706 |
|
| 13 |
V |
A |
-1.1258 |
|
| 14 |
S |
A |
-1.7271 |
|
| 15 |
P |
A |
-1.8665 |
|
| 16 |
G |
A |
-2.1724 |
|
| 17 |
E |
A |
-2.9404 |
|
| 18 |
R |
A |
-3.3870 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.7736 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.8576 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.6547 |
|
| 25 |
A |
A |
-1.4122 |
|
| 26 |
S |
A |
-1.0581 |
|
| 27 |
Q |
A |
-1.6558 |
|
| 28 |
S |
A |
-1.5559 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.0065 |
|
| 31 |
T |
A |
-0.7125 |
|
| 32 |
N |
A |
-0.9246 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.0944 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.5070 |
|
| 39 |
R |
A |
-2.1419 |
|
| 40 |
T |
A |
-1.8064 |
|
| 41 |
N |
A |
-1.9121 |
|
| 42 |
G |
A |
-1.5261 |
|
| 43 |
S |
A |
-1.0848 |
|
| 44 |
P |
A |
-1.0555 |
|
| 45 |
R |
A |
-0.9129 |
|
| 46 |
L |
A |
-0.1624 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.6870 |
|
| 50 |
Y |
A |
-0.0338 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1346 |
|
| 53 |
E |
A |
-1.8736 |
|
| 54 |
S |
A |
-1.0833 |
|
| 55 |
I |
A |
-0.4765 |
|
| 56 |
S |
A |
-0.2360 |
|
| 57 |
G |
A |
-0.3856 |
|
| 58 |
I |
A |
-0.1636 |
|
| 59 |
P |
A |
-0.3194 |
|
| 60 |
S |
A |
-0.6549 |
|
| 61 |
R |
A |
-1.3296 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-1.0492 |
|
| 64 |
G |
A |
-0.6827 |
|
| 65 |
S |
A |
-0.8038 |
|
| 66 |
G |
A |
-1.1169 |
|
| 67 |
S |
A |
-1.1133 |
|
| 68 |
G |
A |
-1.4098 |
|
| 69 |
T |
A |
-2.0591 |
|
| 70 |
D |
A |
-2.8755 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9498 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-1.0080 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.8457 |
|
| 77 |
S |
A |
-2.5050 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.6655 |
|
| 80 |
S |
A |
-2.5332 |
|
| 81 |
E |
A |
-2.5885 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
0.0000 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.8628 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.1252 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.2717 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.4166 |
|
| 92 |
N |
A |
-1.6260 |
|
| 93 |
N |
A |
-1.2292 |
|
| 94 |
W |
A |
0.0667 |
|
| 95 |
P |
A |
-0.1482 |
|
| 96 |
T |
A |
-0.4696 |
|
| 97 |
T |
A |
0.2825 |
|
| 98 |
F |
A |
1.3869 |
|
| 99 |
G |
A |
0.6156 |
|
| 100 |
A |
A |
0.6588 |
|
| 101 |
G |
A |
0.3126 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.2477 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.0879 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.6468 |
|
| 108 |
R |
A |
-1.1665 |
|
| 109 |
T |
A |
-0.1407 |
|
| 110 |
V |
A |
0.2603 |
|
| 111 |
A |
A |
-0.1393 |
|
| 112 |
A |
A |
-0.1898 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.0357 |
|
| 115 |
V |
A |
0.4672 |
|
| 116 |
F |
A |
1.5408 |
|
| 117 |
I |
A |
1.4359 |
|
| 118 |
F |
A |
1.6002 |
|
| 119 |
P |
A |
-0.0000 |
|
| 120 |
P |
A |
-0.6938 |
|
| 121 |
S |
A |
-1.8200 |
|
| 122 |
D |
A |
-3.2679 |
|
| 123 |
E |
A |
-3.4275 |
|
| 124 |
Q |
A |
-2.4615 |
|
| 125 |
L |
A |
-2.5431 |
|
| 126 |
K |
A |
-2.9940 |
|
| 127 |
S |
A |
-1.8399 |
|
| 128 |
G |
A |
-1.4479 |
|
| 129 |
T |
A |
-1.0703 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0196 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7664 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.6134 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.5161 |
|
| 138 |
N |
A |
-1.3259 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
-1.2363 |
|
| 141 |
P |
A |
-1.7624 |
|
| 142 |
R |
A |
-2.9081 |
|
| 143 |
E |
A |
-3.2481 |
|
| 144 |
A |
A |
-2.3320 |
|
| 145 |
K |
A |
-2.2918 |
|
| 146 |
V |
A |
-1.2450 |
|
| 147 |
Q |
A |
-0.8345 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.9251 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.7390 |
|
| 152 |
N |
A |
-1.4126 |
|
| 153 |
A |
A |
-0.4160 |
|
| 154 |
L |
A |
0.4445 |
|
| 155 |
Q |
A |
-0.3780 |
|
| 156 |
S |
A |
-0.4942 |
|
| 157 |
G |
A |
-1.0428 |
|
| 158 |
N |
A |
-1.0730 |
|
| 159 |
S |
A |
-1.4561 |
|
| 160 |
Q |
A |
-2.3103 |
|
| 161 |
E |
A |
-2.3335 |
|
| 162 |
S |
A |
-1.3046 |
|
| 163 |
V |
A |
-0.7347 |
|
| 164 |
T |
A |
-1.0868 |
|
| 165 |
E |
A |
-2.2046 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.4582 |
|
| 168 |
S |
A |
-2.6054 |
|
| 169 |
K |
A |
-2.9159 |
|
| 170 |
D |
A |
-2.2177 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-0.9822 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4718 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.6472 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.5562 |
|
| 181 |
L |
A |
0.0000 |
|
| 182 |
S |
A |
-0.9792 |
|
| 183 |
K |
A |
-1.9092 |
|
| 184 |
A |
A |
-1.6765 |
|
| 185 |
D |
A |
-2.1258 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.5075 |
|
| 188 |
K |
A |
-3.4543 |
|
| 189 |
H |
A |
-2.9680 |
|
| 190 |
K |
A |
-3.1110 |
|
| 191 |
V |
A |
-1.6004 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
-0.9974 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-1.1827 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.2926 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.7571 |
|
| 200 |
G |
A |
-0.4268 |
|
| 201 |
L |
A |
-0.2115 |
|
| 202 |
S |
A |
-0.4391 |
|
| 203 |
S |
A |
-0.4363 |
|
| 204 |
P |
A |
-0.6540 |
|
| 205 |
V |
A |
-0.1736 |
|
| 206 |
T |
A |
-0.4165 |
|
| 207 |
K |
A |
-0.2545 |
|
| 208 |
S |
A |
-0.4240 |
|
| 209 |
F |
A |
-0.7473 |
|
| 210 |
N |
A |
-2.0905 |
|
| 211 |
R |
A |
-2.4447 |
|
| 212 |
G |
A |
-1.3122 |
|