Project name: 5hys:L
Status: done
submitted: 2019-03-21 13:17:17, status changed: 2019-03-21 13:28:46
Settings
|
Chain sequence(s)
|
L: DIQLTQSPSSLSASVGDRVTITCRASQSVDYDGDSYMNWYQQKPGKAPKLLIYAASYLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSHEDPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6267
-
Maximal score value
-
1.5504
-
Average score
-
-0.8715
-
Total score value
-
-189.114
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.8052 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-1.8062 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.8482 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.8085 |
|
| 8 |
P |
L |
-0.5894 |
|
| 9 |
S |
L |
-0.9763 |
|
| 10 |
S |
L |
-1.0898 |
|
| 11 |
L |
L |
-0.7732 |
|
| 12 |
S |
L |
-0.9929 |
|
| 13 |
A |
L |
-1.2123 |
|
| 14 |
S |
L |
-1.1375 |
|
| 15 |
V |
L |
-0.2905 |
|
| 16 |
G |
L |
-1.2454 |
|
| 17 |
D |
L |
-2.5099 |
|
| 18 |
R |
L |
-2.7349 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6772 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.6762 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-1.9940 |
|
| 25 |
A |
L |
-1.7052 |
|
| 26 |
S |
L |
-1.8316 |
|
| 27 |
Q |
L |
-2.2451 |
|
| 28 |
S |
L |
-1.3594 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
D |
L |
-1.4149 |
|
| 31 |
Y |
L |
-0.4587 |
|
| 32 |
D |
L |
-1.8078 |
|
| 33 |
G |
L |
-1.4784 |
|
| 34 |
D |
L |
-1.2815 |
|
| 35 |
S |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.1250 |
|
| 37 |
M |
L |
0.0000 |
|
| 38 |
N |
L |
0.8527 |
|
| 39 |
W |
L |
0.0000 |
|
| 40 |
Y |
L |
0.0542 |
|
| 41 |
Q |
L |
0.0000 |
|
| 42 |
Q |
L |
-1.5396 |
|
| 43 |
K |
L |
-1.9725 |
|
| 44 |
P |
L |
-1.6795 |
|
| 45 |
G |
L |
-1.7010 |
|
| 46 |
K |
L |
-2.3869 |
|
| 47 |
A |
L |
-1.4416 |
|
| 48 |
P |
L |
-1.3478 |
|
| 49 |
K |
L |
-1.6790 |
|
| 50 |
L |
L |
-0.2317 |
|
| 51 |
L |
L |
0.0000 |
|
| 52 |
I |
L |
0.0000 |
|
| 53 |
Y |
L |
1.3136 |
|
| 54 |
A |
L |
0.5058 |
|
| 55 |
A |
L |
0.0000 |
|
| 56 |
S |
L |
0.3551 |
|
| 57 |
Y |
L |
1.2070 |
|
| 58 |
L |
L |
0.8057 |
|
| 59 |
E |
L |
-0.2470 |
|
| 60 |
S |
L |
-0.4823 |
|
| 61 |
G |
L |
-0.6905 |
|
| 62 |
V |
L |
0.0000 |
|
| 63 |
P |
L |
-0.4577 |
|
| 64 |
S |
L |
-0.5263 |
|
| 65 |
R |
L |
-0.8521 |
|
| 66 |
F |
L |
0.0000 |
|
| 67 |
S |
L |
-0.1664 |
|
| 68 |
G |
L |
0.0266 |
|
| 69 |
S |
L |
-0.5849 |
|
| 70 |
G |
L |
-1.0524 |
|
| 71 |
S |
L |
-1.3307 |
|
| 72 |
G |
L |
-1.2928 |
|
| 73 |
T |
L |
-1.6997 |
|
| 74 |
D |
L |
-1.9692 |
|
| 75 |
F |
L |
0.0000 |
|
| 76 |
T |
L |
-0.6894 |
|
| 77 |
L |
L |
0.0000 |
|
| 78 |
T |
L |
-0.6605 |
|
| 79 |
I |
L |
0.0000 |
|
| 80 |
S |
L |
-1.6584 |
|
| 81 |
S |
L |
-1.4827 |
|
| 82 |
L |
L |
0.0000 |
|
| 83 |
Q |
L |
-0.9484 |
|
| 84 |
P |
L |
-1.5937 |
|
| 85 |
E |
L |
-1.7868 |
|
| 86 |
D |
L |
0.0000 |
|
| 87 |
F |
L |
-1.5327 |
|
| 88 |
A |
L |
0.0000 |
|
| 89 |
T |
L |
-1.1445 |
|
| 90 |
Y |
L |
0.0000 |
|
| 91 |
Y |
L |
-0.0496 |
|
| 92 |
C |
L |
0.0000 |
|
| 93 |
Q |
L |
0.0000 |
|
| 94 |
Q |
L |
0.0000 |
|
| 95 |
S |
L |
-0.2284 |
|
| 96 |
H |
L |
-1.1747 |
|
| 97 |
E |
L |
-2.7261 |
|
| 98 |
D |
L |
-2.7224 |
|
| 99 |
P |
L |
-1.4568 |
|
| 100 |
Y |
L |
-0.0319 |
|
| 101 |
T |
L |
0.0841 |
|
| 102 |
F |
L |
1.3724 |
|
| 103 |
G |
L |
0.0000 |
|
| 104 |
Q |
L |
-1.1329 |
|
| 105 |
G |
L |
0.0000 |
|
| 106 |
T |
L |
0.0000 |
|
| 107 |
K |
L |
-2.1536 |
|
| 108 |
V |
L |
0.0000 |
|
| 109 |
E |
L |
-1.6390 |
|
| 110 |
I |
L |
0.0000 |
|
| 111 |
K |
L |
-1.1484 |
|
| 112 |
R |
L |
-0.7299 |
|
| 113 |
T |
L |
-0.0592 |
|
| 114 |
V |
L |
0.2801 |
|
| 115 |
A |
L |
-0.1684 |
|
| 116 |
A |
L |
-0.2189 |
|
| 117 |
P |
L |
0.0000 |
|
| 118 |
S |
L |
-0.0448 |
|
| 119 |
V |
L |
0.4057 |
|
| 120 |
F |
L |
1.3486 |
|
| 121 |
I |
L |
1.3600 |
|
| 122 |
F |
L |
1.5504 |
|
| 123 |
P |
L |
-0.1760 |
|
| 124 |
P |
L |
-0.7248 |
|
| 125 |
S |
L |
-1.7695 |
|
| 126 |
D |
L |
-3.1683 |
|
| 127 |
E |
L |
-3.3627 |
|
| 128 |
Q |
L |
-2.4411 |
|
| 129 |
L |
L |
-2.5351 |
|
| 130 |
K |
L |
-2.9585 |
|
| 131 |
S |
L |
-1.8721 |
|
| 132 |
G |
L |
-1.3803 |
|
| 133 |
T |
L |
-1.1792 |
|
| 134 |
A |
L |
0.0000 |
|
| 135 |
S |
L |
0.0273 |
|
| 136 |
V |
L |
0.0000 |
|
| 137 |
V |
L |
0.7578 |
|
| 138 |
C |
L |
0.0000 |
|
| 139 |
L |
L |
0.5929 |
|
| 140 |
L |
L |
0.0000 |
|
| 141 |
N |
L |
-0.5555 |
|
| 142 |
N |
L |
-1.3081 |
|
| 143 |
F |
L |
0.0000 |
|
| 144 |
Y |
L |
0.0000 |
|
| 145 |
P |
L |
-1.7692 |
|
| 146 |
R |
L |
-2.9746 |
|
| 147 |
E |
L |
-3.1737 |
|
| 148 |
A |
L |
-2.1447 |
|
| 149 |
K |
L |
-1.8455 |
|
| 150 |
V |
L |
-0.9712 |
|
| 151 |
Q |
L |
-0.5985 |
|
| 152 |
W |
L |
0.0000 |
|
| 153 |
K |
L |
-0.5441 |
|
| 154 |
V |
L |
0.0000 |
|
| 155 |
D |
L |
-1.7236 |
|
| 156 |
N |
L |
-1.4706 |
|
| 157 |
A |
L |
-0.2282 |
|
| 158 |
L |
L |
0.7152 |
|
| 159 |
Q |
L |
-0.2840 |
|
| 160 |
S |
L |
-0.8216 |
|
| 161 |
G |
L |
-1.3710 |
|
| 162 |
N |
L |
-1.7103 |
|
| 163 |
S |
L |
-1.7934 |
|
| 164 |
Q |
L |
-2.4778 |
|
| 165 |
E |
L |
-2.3257 |
|
| 166 |
S |
L |
-1.2823 |
|
| 167 |
V |
L |
-0.7105 |
|
| 168 |
T |
L |
-1.2690 |
|
| 169 |
E |
L |
-2.4246 |
|
| 170 |
Q |
L |
0.0000 |
|
| 171 |
D |
L |
-2.5758 |
|
| 172 |
S |
L |
-2.4295 |
|
| 173 |
K |
L |
-2.7219 |
|
| 174 |
D |
L |
-2.0921 |
|
| 175 |
S |
L |
0.0000 |
|
| 176 |
T |
L |
0.0000 |
|
| 177 |
Y |
L |
0.0000 |
|
| 178 |
S |
L |
-1.0331 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
S |
L |
-0.4269 |
|
| 181 |
S |
L |
0.0000 |
|
| 182 |
T |
L |
-0.7186 |
|
| 183 |
L |
L |
0.0000 |
|
| 184 |
T |
L |
-0.6554 |
|
| 185 |
L |
L |
-0.8522 |
|
| 186 |
S |
L |
-1.3165 |
|
| 187 |
K |
L |
-2.3399 |
|
| 188 |
A |
L |
-1.9670 |
|
| 189 |
D |
L |
-2.5431 |
|
| 190 |
Y |
L |
0.0000 |
|
| 191 |
E |
L |
-3.5792 |
|
| 192 |
K |
L |
-3.6267 |
|
| 193 |
H |
L |
-3.1229 |
|
| 194 |
K |
L |
-3.5098 |
|
| 195 |
V |
L |
-1.7645 |
|
| 196 |
Y |
L |
0.0000 |
|
| 197 |
A |
L |
0.0000 |
|
| 198 |
C |
L |
0.0000 |
|
| 199 |
E |
L |
-0.8635 |
|
| 200 |
V |
L |
0.0000 |
|
| 201 |
T |
L |
-1.0289 |
|
| 202 |
H |
L |
0.0000 |
|
| 203 |
Q |
L |
-1.7185 |
|
| 204 |
G |
L |
-0.4639 |
|
| 205 |
L |
L |
-0.2404 |
|
| 206 |
S |
L |
-0.4484 |
|
| 207 |
S |
L |
-0.3922 |
|
| 208 |
P |
L |
-0.4734 |
|
| 209 |
V |
L |
-0.0501 |
|
| 210 |
T |
L |
-0.4035 |
|
| 211 |
K |
L |
-0.3506 |
|
| 212 |
S |
L |
-0.4344 |
|
| 213 |
F |
L |
-1.1196 |
|
| 214 |
N |
L |
-2.5163 |
|
| 215 |
R |
L |
-3.0965 |
|
| 216 |
G |
L |
-2.3973 |
|
| 217 |
E |
L |
-2.7224 |
|