Project name: 3qwo:H
Status: done
submitted: 2019-03-20 15:36:57, status changed: 2019-03-20 17:17:24
Settings
|
Chain sequence(s)
|
H: QVTLRESGPALVKPTQTLTLTCTFSGFSLSTAGMSVGWIRQPPGKALEWLADIWWDDKKHYNPSLKDRLTISKDTSKNQVVLKVTNMDPADTATYYCARDMIFNFYFDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5785
-
Maximal score value
-
3.2072
-
Average score
-
-0.5295
-
Total score value
-
-116.4906
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
H |
-1.2561 |
|
| 2 |
V |
H |
-0.6355 |
|
| 3 |
T |
H |
-0.7379 |
|
| 4 |
L |
H |
0.0000 |
|
| 5 |
R |
H |
-1.7792 |
|
| 6 |
E |
H |
0.0000 |
|
| 7 |
S |
H |
-0.5209 |
|
| 8 |
G |
H |
-0.2051 |
|
| 9 |
P |
H |
-0.3248 |
|
| 10 |
A |
H |
-0.3947 |
|
| 11 |
L |
H |
-0.2831 |
|
| 12 |
V |
H |
0.0000 |
|
| 13 |
K |
H |
-2.3583 |
|
| 14 |
P |
H |
-2.0130 |
|
| 15 |
T |
H |
-1.9281 |
|
| 16 |
Q |
H |
-2.1956 |
|
| 17 |
T |
H |
-1.6050 |
|
| 18 |
L |
H |
0.0000 |
|
| 19 |
T |
H |
-0.5106 |
|
| 20 |
L |
H |
0.0000 |
|
| 21 |
T |
H |
-0.4201 |
|
| 22 |
C |
H |
0.0000 |
|
| 23 |
T |
H |
-1.1027 |
|
| 24 |
F |
H |
0.0000 |
|
| 25 |
S |
H |
-1.0452 |
|
| 26 |
G |
H |
-0.8795 |
|
| 27 |
F |
H |
-0.3683 |
|
| 28 |
S |
H |
-0.4361 |
|
| 29 |
L |
H |
0.0000 |
|
| 30 |
S |
H |
-0.7554 |
|
| 31 |
T |
H |
-0.2183 |
|
| 32 |
A |
H |
-0.0698 |
|
| 33 |
G |
H |
0.0000 |
|
| 34 |
M |
H |
0.0000 |
|
| 35 |
S |
H |
0.0000 |
|
| 35A |
V |
H |
0.0000 |
|
| 35B |
G |
H |
0.0000 |
|
| 36 |
W |
H |
0.0000 |
|
| 37 |
I |
H |
0.0000 |
|
| 38 |
R |
H |
0.0000 |
|
| 39 |
Q |
H |
-0.5662 |
|
| 40 |
P |
H |
-0.8754 |
|
| 41 |
P |
H |
-1.1198 |
|
| 42 |
G |
H |
-1.3505 |
|
| 43 |
K |
H |
-1.8659 |
|
| 44 |
A |
H |
-0.4882 |
|
| 45 |
L |
H |
0.5690 |
|
| 46 |
E |
H |
-0.0229 |
|
| 47 |
W |
H |
0.4021 |
|
| 48 |
L |
H |
0.0000 |
|
| 49 |
A |
H |
0.0000 |
|
| 50 |
D |
H |
0.0000 |
|
| 51 |
I |
H |
0.0000 |
|
| 52 |
W |
H |
0.0000 |
|
| 53 |
W |
H |
-1.4509 |
|
| 54 |
D |
H |
-3.0894 |
|
| 55 |
D |
H |
-3.5785 |
|
| 56 |
K |
H |
-3.4066 |
|
| 57 |
K |
H |
-2.1387 |
|
| 58 |
H |
H |
-0.8547 |
|
| 59 |
Y |
H |
-0.5275 |
|
| 60 |
N |
H |
-0.8207 |
|
| 61 |
P |
H |
-1.3238 |
|
| 62 |
S |
H |
-1.1168 |
|
| 63 |
L |
H |
0.0000 |
|
| 64 |
K |
H |
-2.7568 |
|
| 65 |
D |
H |
-2.7832 |
|
| 66 |
R |
H |
-2.1385 |
|
| 67 |
L |
H |
0.0000 |
|
| 68 |
T |
H |
-0.7152 |
|
| 69 |
I |
H |
0.0000 |
|
| 70 |
S |
H |
-1.0524 |
|
| 71 |
K |
H |
-1.3067 |
|
| 72 |
D |
H |
-1.5089 |
|
| 73 |
T |
H |
-1.2442 |
|
| 74 |
S |
H |
-1.4527 |
|
| 75 |
K |
H |
-2.3035 |
|
| 76 |
N |
H |
-1.6646 |
|
| 77 |
Q |
H |
-1.4574 |
|
| 78 |
V |
H |
0.0000 |
|
| 79 |
V |
H |
-0.1297 |
|
| 80 |
L |
H |
0.0000 |
|
| 81 |
K |
H |
-0.9291 |
|
| 82 |
V |
H |
0.0000 |
|
| 82A |
T |
H |
-1.8513 |
|
| 82B |
N |
H |
-2.2618 |
|
| 82C |
M |
H |
0.0000 |
|
| 83 |
D |
H |
-2.1578 |
|
| 84 |
P |
H |
-1.1251 |
|
| 85 |
A |
H |
-0.5195 |
|
| 86 |
D |
H |
0.0000 |
|
| 87 |
T |
H |
-0.4187 |
|
| 88 |
A |
H |
0.0000 |
|
| 89 |
T |
H |
-0.1720 |
|
| 90 |
Y |
H |
0.0000 |
|
| 91 |
Y |
H |
-0.1465 |
|
| 92 |
C |
H |
0.0000 |
|
| 93 |
A |
H |
0.0000 |
|
| 94 |
R |
H |
0.0000 |
|
| 95 |
D |
H |
0.0000 |
|
| 96 |
M |
H |
1.9856 |
|
| 97 |
I |
H |
2.7517 |
|
| 98 |
F |
H |
2.9762 |
|
| 99 |
N |
H |
2.2956 |
|
| 100 |
F |
H |
3.2072 |
|
| 100A |
Y |
H |
2.5543 |
|
| 100B |
F |
H |
1.1857 |
|
| 101 |
D |
H |
0.1274 |
|
| 102 |
V |
H |
0.1462 |
|
| 103 |
W |
H |
-0.0037 |
|
| 104 |
G |
H |
-0.8252 |
|
| 105 |
Q |
H |
-1.4223 |
|
| 106 |
G |
H |
0.0000 |
|
| 107 |
T |
H |
-0.5676 |
|
| 108 |
T |
H |
-0.3441 |
|
| 109 |
V |
H |
0.0000 |
|
| 110 |
T |
H |
-0.5062 |
|
| 111 |
V |
H |
0.0000 |
|
| 112 |
S |
H |
-0.9373 |
|
| 113 |
S |
H |
-0.7970 |
|
| 114 |
A |
H |
-0.5585 |
|
| 115 |
S |
H |
-0.7313 |
|
| 116 |
T |
H |
-0.8294 |
|
| 117 |
K |
H |
-1.7019 |
|
| 118 |
G |
H |
-1.8451 |
|
| 119 |
P |
H |
-0.9621 |
|
| 120 |
S |
H |
-0.2837 |
|
| 121 |
V |
H |
0.0000 |
|
| 122 |
F |
H |
1.0681 |
|
| 123 |
P |
H |
0.0412 |
|
| 124 |
L |
H |
0.2794 |
|
| 125 |
A |
H |
-0.5394 |
|
| 126 |
P |
H |
0.0000 |
|
| 127 |
S |
H |
-1.0970 |
|
| 128 |
S |
H |
-1.2115 |
|
| 129 |
K |
H |
-1.9292 |
|
| 130 |
S |
H |
-1.0380 |
|
| 131 |
T |
H |
-1.0570 |
|
| 132 |
S |
H |
-0.9321 |
|
| 133 |
G |
H |
-0.9220 |
|
| 134 |
G |
H |
-0.9629 |
|
| 135 |
T |
H |
-0.6541 |
|
| 136 |
A |
H |
0.0000 |
|
| 137 |
A |
H |
-0.2289 |
|
| 138 |
L |
H |
0.0000 |
|
| 139 |
G |
H |
0.0000 |
|
| 140 |
C |
H |
0.0000 |
|
| 141 |
L |
H |
0.6285 |
|
| 142 |
V |
H |
0.0000 |
|
| 143 |
K |
H |
-0.5476 |
|
| 144 |
D |
H |
-1.2469 |
|
| 145 |
Y |
H |
0.0000 |
|
| 146 |
F |
H |
0.0000 |
|
| 147 |
P |
H |
0.0000 |
|
| 148 |
E |
H |
-0.6077 |
|
| 149 |
P |
H |
-0.7558 |
|
| 150 |
V |
H |
-0.6140 |
|
| 151 |
T |
H |
-0.7256 |
|
| 152 |
V |
H |
-0.2960 |
|
| 153 |
S |
H |
-0.4383 |
|
| 154 |
W |
H |
0.0000 |
|
| 155 |
N |
H |
-0.7753 |
|
| 156 |
S |
H |
-0.6469 |
|
| 157 |
G |
H |
-0.5403 |
|
| 158 |
A |
H |
-0.2553 |
|
| 159 |
L |
H |
-0.0562 |
|
| 160 |
T |
H |
-0.3043 |
|
| 161 |
S |
H |
-0.3718 |
|
| 162 |
G |
H |
-0.4562 |
|
| 163 |
V |
H |
0.0722 |
|
| 164 |
H |
H |
-0.3172 |
|
| 165 |
T |
H |
0.3045 |
|
| 166 |
F |
H |
1.1102 |
|
| 167 |
P |
H |
0.8130 |
|
| 168 |
A |
H |
1.3339 |
|
| 169 |
V |
H |
2.5575 |
|
| 170 |
L |
H |
2.1693 |
|
| 171 |
Q |
H |
0.6497 |
|
| 172 |
S |
H |
0.1001 |
|
| 173 |
S |
H |
-0.2986 |
|
| 174 |
G |
H |
0.1306 |
|
| 175 |
L |
H |
0.0742 |
|
| 176 |
Y |
H |
0.6839 |
|
| 177 |
S |
H |
0.0000 |
|
| 178 |
L |
H |
0.0000 |
|
| 179 |
S |
H |
0.6646 |
|
| 180 |
S |
H |
0.0000 |
|
| 181 |
V |
H |
0.4829 |
|
| 182 |
V |
H |
0.0000 |
|
| 183 |
T |
H |
-0.2980 |
|
| 184 |
V |
H |
0.0000 |
|
| 185 |
P |
H |
-0.6165 |
|
| 186 |
S |
H |
-0.5796 |
|
| 187 |
S |
H |
-0.5299 |
|
| 188 |
S |
H |
-0.4898 |
|
| 189 |
L |
H |
-0.6974 |
|
| 190 |
G |
H |
-0.8933 |
|
| 191 |
T |
H |
-0.6000 |
|
| 192 |
Q |
H |
-1.0140 |
|
| 193 |
T |
H |
-1.0345 |
|
| 194 |
Y |
H |
0.0000 |
|
| 195 |
I |
H |
-1.4036 |
|
| 196 |
C |
H |
0.0000 |
|
| 197 |
N |
H |
-1.6010 |
|
| 198 |
V |
H |
0.0000 |
|
| 199 |
N |
H |
-2.3749 |
|
| 200 |
H |
H |
0.0000 |
|
| 201 |
K |
H |
-2.9012 |
|
| 202 |
P |
H |
-1.6847 |
|
| 203 |
S |
H |
-2.0113 |
|
| 204 |
N |
H |
-2.7066 |
|
| 205 |
T |
H |
-2.2939 |
|
| 206 |
K |
H |
-2.9121 |
|
| 207 |
V |
H |
-1.6995 |
|
| 208 |
D |
H |
-2.4646 |
|
| 209 |
K |
H |
-2.1273 |
|
| 210 |
K |
H |
-2.4487 |
|
| 211 |
V |
H |
0.0000 |
|
| 212 |
E |
H |
-2.4344 |
|
| 213 |
P |
H |
-1.1617 |
|