Project name: 5E Casey

Chain sequence(s)	A: MKSILLSFLLGLICVPLVQTDVLVQPDFDAKQFSGLWYVVSMVSDCKVFLGKKESILMSTRLINATEGGNLTVHMAFPGADGCKTMDAEYIKIGSEGHFKVSSFLANGFLDVRVAETDYNSYCILYIYKELDGVFSTMVQLFSRTQGVSGKALRAFQDFYPIVGLEDDMMSLLSKSDACSQENIEVS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7442
• Maximal score value: 3.5595
• Average score: -0.3062
• Total score value: -57.2575

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	2.9058
2	K	A	2.7633
3	S	A	0.0000
4	I	A	0.0000
5	L	A	3.0416
6	L	A	3.5595
7	S	A	2.6812
8	F	A	3.1135
9	L	A	2.7253
10	L	A	2.6012
11	G	A	2.0935
12	L	A	2.5014
13	I	A	3.1908
14	C	A	3.0220
15	V	A	3.0741
16	P	A	0.0000
17	L	A	0.0000
18	V	A	1.0875
19	Q	A	0.0000
20	T	A	0.0510
21	D	A	-1.2290
22	V	A	0.2056
23	L	A	1.2628
24	V	A	0.7546
25	Q	A	-0.6900
26	P	A	-1.0232
27	D	A	-2.3377
28	F	A	-1.9058
29	D	A	-2.2750
30	A	A	-1.8391
31	K	A	-2.5946
32	Q	A	-2.3151
33	F	A	0.0000
34	S	A	-1.1321
35	G	A	-0.6355
36	L	A	0.0670
37	W	A	0.0000
38	Y	A	-0.3101
39	V	A	0.0000
40	V	A	0.0000
41	S	A	0.0000
42	M	A	0.0000
43	V	A	0.0000
44	S	A	0.0000
45	D	A	-0.9399
46	C	A	-0.1791
47	K	A	-1.0683
48	V	A	0.4457
49	F	A	-0.1852
50	L	A	0.0000
51	G	A	-1.3374
52	K	A	-2.3971
53	K	A	-2.4342
54	E	A	-1.3128
55	S	A	-0.7553
56	I	A	0.0000
57	L	A	-0.2313
58	M	A	0.2290
59	S	A	0.0000
60	T	A	0.0000
61	R	A	0.0000
62	L	A	0.0182
63	I	A	0.0000
64	N	A	-1.4139
65	A	A	-1.4802
66	T	A	-1.6981
67	E	A	-2.2324
68	G	A	-1.5120
69	G	A	-1.3286
70	N	A	-1.1624
71	L	A	0.0000
72	T	A	-1.1663
73	V	A	0.0000
74	H	A	-1.0498
75	M	A	0.0000
76	A	A	0.0000
77	F	A	-0.1326
78	P	A	-1.3477
79	G	A	-1.4778
80	A	A	-1.5261
81	D	A	-2.1814
82	G	A	-1.3532
83	C	A	-0.9593
84	K	A	-0.8934
85	T	A	-0.7279
86	M	A	-0.7796
87	D	A	-2.0210
88	A	A	-1.4986
89	E	A	-1.8157
90	Y	A	-0.4497
91	I	A	0.0055
92	K	A	-0.8017
93	I	A	-0.0465
94	G	A	-0.6325
95	S	A	-1.0614
96	E	A	-2.3703
97	G	A	0.0000
98	H	A	-0.5902
99	F	A	0.0000
100	K	A	-0.1380
101	V	A	0.0000
102	S	A	0.8713
103	S	A	1.2812
104	F	A	2.7663
105	L	A	2.4962
106	A	A	1.2808
107	N	A	0.4169
108	G	A	0.8243
109	F	A	1.0240
110	L	A	0.0000
111	D	A	0.0000
112	V	A	0.0000
113	R	A	0.0000
114	V	A	0.0000
115	A	A	0.0000
116	E	A	-0.0347
117	T	A	0.0000
118	D	A	-1.4936
119	Y	A	-1.2380
120	N	A	-1.6581
121	S	A	-1.0475
122	Y	A	-0.6051
123	C	A	0.0000
124	I	A	0.0000
125	L	A	0.0000
126	Y	A	0.0000
127	I	A	0.0000
128	Y	A	0.0000
129	K	A	0.0000
130	E	A	0.2220
131	L	A	0.0823
132	D	A	-1.2361
133	G	A	-0.3172
134	V	A	1.3250
135	F	A	1.5969
136	S	A	0.0000
137	T	A	0.0000
138	M	A	0.0000
139	V	A	0.0000
140	Q	A	0.0000
141	L	A	0.0000
142	F	A	0.0000
143	S	A	0.0000
144	R	A	-1.0428
145	T	A	-1.0239
146	Q	A	-1.4621
147	G	A	-1.1784
148	V	A	-0.6789
149	S	A	-1.0254
150	G	A	-1.5335
151	K	A	-2.2338
152	A	A	0.0000
153	L	A	-0.9512
154	R	A	-1.9067
155	A	A	-1.3949
156	F	A	0.0000
157	Q	A	-1.2597
158	D	A	-1.1444
159	F	A	0.0000
160	Y	A	0.0000
161	P	A	-0.8301
162	I	A	0.1083
163	V	A	0.0000
164	G	A	-0.6399
165	L	A	0.0000
166	E	A	-2.7442
167	D	A	-2.4399
168	D	A	-2.7248
169	M	A	-1.5832
170	M	A	-0.8680
171	S	A	-0.2263
172	L	A	0.4236
173	L	A	0.0000
174	S	A	-1.3548
175	K	A	-2.1561
176	S	A	-1.8374
177	D	A	-2.5223
178	A	A	-1.5021
179	C	A	0.0000
180	S	A	-1.2609
181	Q	A	-1.3598
182	E	A	-0.8227
183	N	A	-0.2469
184	I	A	0.7647
185	E	A	-0.6436
186	V	A	0.8994
187	S	A	0.1643