Project name: 5t1m:B

Chain sequence(s)	B: VQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.861
• Maximal score value: 2.4215
• Average score: -0.4918
• Total score value: -107.2105

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	B	0.6848
3	Q	B	-1.0804
4	L	B	0.0000
5	K	B	-2.3303
6	Q	B	0.0000
7	S	B	-0.7338
8	G	B	-0.9508
9	P	B	-0.3839
10	G	B	-0.3300
11	L	B	-0.1189
12	V	B	0.0000
13	Q	B	-1.7721
14	P	B	-1.5537
15	S	B	-1.5301
16	Q	B	-1.8562
17	S	B	-1.5305
18	L	B	0.0000
19	S	B	-0.6103
20	I	B	0.0000
21	T	B	-0.4887
22	C	B	0.0000
23	T	B	-1.1987
24	V	B	0.0000
25	S	B	-0.7815
26	G	B	-0.1720
27	F	B	-0.1462
28	S	B	-0.7518
29	L	B	0.0000
30	T	B	-0.8951
31	N	B	-0.8540
32	Y	B	0.4541
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.4730
40	S	B	-1.0339
41	P	B	-1.1350
42	G	B	-1.6580
43	K	B	-2.0887
44	G	B	-0.7480
45	L	B	0.6074
46	E	B	-0.0746
47	W	B	0.3159
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.5785
53	S	B	-0.5683
54	G	B	-1.2118
55	G	B	-1.5085
56	N	B	-1.9797
57	T	B	-1.6072
58	D	B	-1.7038
59	Y	B	-0.7835
60	N	B	-0.7051
61	T	B	-0.5447
62	P	B	-0.4656
63	F	B	0.0000
64	T	B	-0.6367
65	S	B	-0.5950
66	R	B	-0.9550
67	L	B	0.0000
68	S	B	-1.0563
69	I	B	0.0000
70	N	B	-1.6923
71	K	B	-1.4011
72	D	B	-1.7484
73	N	B	-2.1698
74	S	B	-1.6624
75	K	B	-2.3466
76	S	B	-1.5830
77	Q	B	-1.4992
78	V	B	0.0000
79	F	B	-0.2659
80	F	B	0.0000
81	K	B	-1.3697
82	M	B	0.0000
83	N	B	-1.5645
84	S	B	-1.4436
85	L	B	0.0000
86	Q	B	-2.1019
87	S	B	-1.5528
88	N	B	-2.0609
89	D	B	0.0000
90	T	B	-0.6900
91	A	B	0.0000
92	I	B	0.4494
93	Y	B	0.0000
94	Y	B	-0.1226
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.6861
100	T	B	1.3456
101	Y	B	1.9403
102	Y	B	1.7971
103	D	B	0.8498
104	Y	B	0.7073
105	E	B	-0.1660
106	F	B	0.5411
107	A	B	0.8708
108	Y	B	0.7614
109	W	B	0.1545
110	G	B	0.0000
111	Q	B	-1.5265
112	G	B	-0.6334
113	T	B	0.0000
114	L	B	0.3721
115	V	B	0.0000
116	T	B	0.0000
117	V	B	0.0000
118	S	B	-0.6393
119	A	B	-0.4175
120	A	B	-0.3966
121	S	B	-0.5991
122	T	B	-0.8383
123	K	B	-1.4490
124	G	B	-1.6010
125	P	B	-0.6666
126	S	B	-0.0765
127	V	B	0.0000
128	F	B	1.0984
129	P	B	-0.0986
130	L	B	0.3327
131	A	B	-0.8738
132	P	B	0.0000
133	S	B	-0.8745
134	S	B	-0.4545
136	S	B	-0.3740
137	T	B	-0.6163
138	S	B	-0.7301
139	G	B	-0.8572
140	G	B	-0.9631
141	T	B	-0.7095
142	A	B	0.0000
143	A	B	-0.0377
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.6836
148	V	B	0.0000
149	K	B	-0.2087
150	D	B	-0.7976
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.0578
155	P	B	-0.4521
156	V	B	-0.5964
157	T	B	-0.5890
158	V	B	-0.2743
159	S	B	-0.5048
160	W	B	0.0000
161	N	B	-0.8209
162	S	B	-0.7011
163	G	B	-0.5899
164	A	B	-0.2531
165	L	B	-0.0317
166	T	B	-0.2960
167	S	B	-0.3629
168	G	B	-0.4564
169	V	B	0.0467
170	H	B	-0.3342
171	T	B	0.2813
172	F	B	1.0829
173	P	B	0.7669
174	A	B	1.3133
175	V	B	2.4215
176	L	B	1.9419
177	Q	B	0.5242
178	S	B	-0.0164
179	S	B	-0.3458
180	G	B	0.0044
181	L	B	0.1140
182	Y	B	0.7122
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6936
186	S	B	0.0000
187	V	B	0.4711
188	V	B	0.0000
189	T	B	-0.2425
190	V	B	0.0000
191	P	B	-0.5470
192	S	B	-0.6356
193	S	B	-0.6052
194	S	B	-0.6002
195	L	B	-0.8013
196	G	B	-0.9575
197	T	B	-0.7623
198	Q	B	-1.2822
199	T	B	-1.1629
200	Y	B	0.0000
201	I	B	-1.4667
202	C	B	0.0000
203	N	B	-1.6033
204	V	B	0.0000
205	N	B	-2.0102
206	H	B	0.0000
207	K	B	-2.8164
208	P	B	-1.6279
209	S	B	-1.9453
210	N	B	-2.6403
211	T	B	-2.0982
212	K	B	-2.7093
213	V	B	-1.7209
214	D	B	-2.6390
215	K	B	-2.0032
216	R	B	-2.6592
217	V	B	0.0000
218	E	B	-2.8610
219	P	B	-1.8746
220	K	B	-2.2219