Project name: 4mjh

Chain sequence(s)	A: VSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMP; C: SEIRRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPM; B: ITIPVTF; D: ITIPVTF
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.0355
• Maximal score value: 1.8416
• Average score: -1.009
• Total score value: -181.6203

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
85	V	A	0.9212
86	S	A	-0.4385
87	E	A	-1.5410
88	I	A	-1.3788
89	R	A	-2.7723
90	H	A	-2.7481
91	T	A	-1.9358
92	A	A	-1.5279
93	D	A	-2.4261
94	R	A	-2.5968
95	W	A	0.0000
96	R	A	-2.3030
97	V	A	0.0000
98	S	A	-1.0423
99	L	A	0.0000
100	D	A	-1.2969
101	V	A	0.0000
102	N	A	-2.2288
103	H	A	-2.1010
104	F	A	-1.5611
105	A	A	-1.2875
106	P	A	-0.8125
107	D	A	-2.2016
108	E	A	-2.1454
109	L	A	0.0000
110	T	A	-0.8458
111	V	A	0.0000
112	K	A	-0.3265
113	T	A	0.0000
114	K	A	-2.2464
115	D	A	-2.5571
116	G	A	-1.6424
117	V	A	-0.9304
118	V	A	0.0000
119	E	A	0.0000
120	I	A	0.0000
121	T	A	-0.5712
122	G	A	0.0000
123	K	A	-2.6919
124	H	A	0.0000
125	E	A	-3.7101
126	E	A	-4.0355
127	R	A	-3.7936
128	Q	A	-3.1935
129	D	A	-2.6004
130	E	A	-2.5626
131	H	A	-1.8283
132	G	A	-1.6385
133	Y	A	-1.9055
134	I	A	0.0000
135	S	A	-2.4136
136	R	A	-1.8464
137	C	A	-1.0262
138	F	A	-0.6885
139	T	A	-0.5048
140	R	A	0.0000
141	K	A	-0.4882
142	Y	A	0.0000
143	T	A	-0.4209
144	L	A	0.0000
145	P	A	-0.6129
146	P	A	-0.9922
147	G	A	-1.0354
148	V	A	0.0000
149	D	A	-2.6151
150	P	A	-1.6239
151	T	A	-0.9692
152	Q	A	-1.6294
153	V	A	0.0000
154	S	A	-0.8580
155	S	A	0.0000
156	S	A	0.2583
157	L	A	0.0000
158	S	A	-0.6171
159	P	A	-0.9739
160	E	A	-2.5374
161	G	A	-1.8581
162	T	A	-1.3456
163	L	A	0.0000
164	T	A	-0.8316
165	V	A	0.0000
166	E	A	-1.7783
167	A	A	0.0000
168	P	A	-1.7515
169	M	A	-1.3354
170	P	A	-0.9486
179	I	B	1.8291
180	T	B	0.7950
181	I	B	0.0000
182	P	B	0.1165
183	V	B	0.1546
184	T	B	0.4612
185	F	B	0.9819
86	S	C	-1.4907
87	E	C	-2.2936
88	I	C	-1.7874
89	R	C	-2.7213
94	R	C	-2.3537
95	W	C	0.0000
96	R	C	-2.7775
97	V	C	0.0000
98	S	C	-1.5165
99	L	C	-1.2739
100	D	C	-2.5924
101	V	C	0.0000
102	N	C	-2.3912
103	H	C	-1.6767
104	F	C	-1.3457
105	A	C	-1.1820
106	P	C	-0.8140
107	D	C	-2.1922
108	E	C	-2.0281
109	L	C	0.0000
110	T	C	-0.9766
111	V	C	0.0000
112	K	C	-0.8372
113	T	C	0.0000
114	K	C	-2.1120
115	D	C	-2.2926
116	G	C	-1.5612
117	V	C	-1.2745
118	V	C	0.0000
119	E	C	-1.0938
120	I	C	0.0000
121	T	C	-0.7062
122	G	C	0.0000
123	K	C	-2.1808
124	H	C	0.0000
125	E	C	-2.8386
126	E	C	-2.5143
127	R	C	-2.1632
128	Q	C	-2.5927
129	D	C	-2.6481
130	E	C	-2.5938
131	H	C	-1.6928
132	G	C	-1.3355
133	Y	C	-1.3098
134	I	C	0.0000
135	S	C	-1.5739
136	R	C	-1.3182
137	C	C	-0.8949
138	F	C	-0.7895
139	T	C	-0.7922
140	R	C	0.0000
141	K	C	-1.1490
142	Y	C	0.0000
143	T	C	-0.5897
144	L	C	0.0000
145	P	C	-0.4664
146	P	C	-0.5243
147	G	C	-0.6579
148	V	C	0.0000
149	D	C	-1.2057
150	P	C	-1.2898
151	T	C	-0.6426
152	Q	C	-1.5492
153	V	C	0.0000
154	S	C	-1.0356
155	S	C	0.0000
156	S	C	0.2993
157	L	C	0.0000
158	S	C	-0.6265
159	P	C	-0.8966
160	E	C	-2.5253
161	G	C	0.0000
162	T	C	-1.6614
163	L	C	0.0000
164	T	C	-0.9268
165	V	C	0.0000
166	E	C	-2.2868
167	A	C	0.0000
168	P	C	-1.2683
169	M	C	-0.0237
179	I	D	1.8416
180	T	D	0.8118
181	I	D	0.0000
182	P	D	-0.1176
183	V	D	-0.0475
184	T	D	0.2827
185	F	D	0.7738