Project name: 5hyq:A

Chain sequence(s)	A: DILLTQSPVILSVSPGERVSFSSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8591
• Maximal score value: 1.9044
• Average score: -0.8568
• Total score value: -182.5021

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-1.4650
2	I	A	0.0000
3	L	A	0.7496
4	L	A	0.0000
5	T	A	-0.2695
6	Q	A	0.0770
7	S	A	0.1052
8	P	A	0.8252
9	V	A	1.9044
10	I	A	1.3550
11	L	A	0.6033
12	S	A	-0.3242
13	V	A	-1.2912
14	S	A	-1.7510
15	P	A	-1.9824
16	G	A	-2.2380
17	E	A	-3.0661
18	R	A	-3.4151
19	V	A	0.0000
20	S	A	-0.7779
21	F	A	0.0000
22	S	A	-0.7924
23	C	A	0.0000
24	R	A	-2.5229
25	A	A	-1.3622
26	S	A	-1.0678
27	Q	A	-1.9567
28	S	A	-1.7036
29	I	A	0.0000
30	G	A	-1.1472
31	T	A	-0.7916
32	N	A	-1.0810
33	I	A	0.0000
34	H	A	0.0000
35	W	A	0.0000
36	Y	A	0.0177
37	Q	A	0.0000
38	Q	A	-1.3449
39	R	A	-1.9819
40	T	A	-1.8128
41	N	A	-1.9411
42	G	A	-1.4921
43	S	A	-1.0250
44	P	A	-0.9164
45	R	A	-0.6871
46	L	A	-0.0686
47	L	A	0.0000
48	I	A	0.0000
49	K	A	-0.8290
50	Y	A	-0.3792
51	A	A	0.0000
52	S	A	-1.1665
53	E	A	-1.9537
54	S	A	-1.1108
55	I	A	-0.4959
56	S	A	-0.4314
57	G	A	-0.3969
58	I	A	-0.1388
59	P	A	-0.3023
60	S	A	-0.6079
61	R	A	-1.2061
62	F	A	0.0000
63	S	A	-0.9783
64	G	A	-0.6936
65	S	A	-0.7628
66	G	A	-1.0095
67	S	A	-1.0765
68	G	A	-1.3918
69	T	A	-1.9413
70	D	A	-2.5002
71	F	A	0.0000
72	T	A	-0.8646
73	L	A	0.0000
74	S	A	-0.9717
75	I	A	0.0000
76	N	A	-2.7755
77	S	A	-2.5011
78	V	A	0.0000
79	E	A	-2.4724
80	S	A	-2.2463
81	E	A	-2.1794
82	D	A	0.0000
83	I	A	-1.5376
84	A	A	0.0000
85	D	A	-0.5897
86	Y	A	0.0000
87	Y	A	0.2403
88	C	A	0.0000
89	Q	A	0.3091
90	Q	A	0.0000
91	N	A	-1.4312
92	N	A	-1.8646
93	N	A	-1.5296
94	W	A	-0.0461
95	P	A	-0.2015
96	T	A	-0.4717
97	T	A	0.3043
98	F	A	1.4775
99	G	A	0.6658
100	A	A	0.6481
101	G	A	0.4191
102	T	A	0.0000
103	K	A	-0.0559
104	L	A	0.0000
105	E	A	-1.0135
106	L	A	0.0000
107	K	A	-1.5119
108	R	A	-1.1039
109	T	A	-0.1748
110	V	A	0.1305
111	A	A	-0.0537
112	A	A	-0.2845
113	P	A	0.0000
114	S	A	-0.1789
115	V	A	0.0000
116	F	A	1.2168
117	I	A	1.2680
118	F	A	1.5366
119	P	A	0.0611
120	P	A	0.0000
121	S	A	-1.8179
122	D	A	-3.2522
123	E	A	-3.4620
124	Q	A	-2.5487
125	L	A	-2.6433
126	K	A	-3.0520
127	S	A	-1.9204
128	G	A	-1.5297
129	T	A	-1.2350
130	A	A	0.0000
131	S	A	0.0536
132	V	A	0.0000
133	V	A	0.7813
134	C	A	0.0000
135	L	A	0.4723
136	L	A	0.0000
137	N	A	-0.6782
138	N	A	-1.3295
139	F	A	0.0000
140	Y	A	0.0000
141	P	A	-1.7925
142	R	A	-2.9473
143	E	A	-3.2547
144	A	A	-2.3455
145	K	A	-2.1719
146	V	A	-1.1757
147	Q	A	-0.7845
148	W	A	0.0000
149	K	A	-0.6546
150	V	A	0.0000
151	D	A	-1.7740
152	N	A	-1.2913
153	A	A	-0.2407
154	L	A	0.7074
155	Q	A	-0.2409
156	S	A	-0.4236
157	G	A	-1.0349
158	N	A	-1.0213
159	S	A	-1.4052
160	Q	A	-2.2474
161	E	A	-2.2267
162	S	A	-1.2911
163	V	A	-0.8290
164	T	A	-1.2638
165	E	A	-2.4662
166	Q	A	0.0000
167	D	A	-2.3870
168	S	A	-2.4314
169	K	A	-2.7322
170	D	A	-2.0011
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	-1.5912
174	S	A	-1.0305
175	L	A	0.0000
176	S	A	-0.4891
177	S	A	0.0000
178	T	A	-0.5558
179	L	A	0.0000
180	T	A	-0.5554
181	L	A	-0.8107
182	S	A	-1.2607
183	K	A	-2.3432
184	A	A	-2.1907
185	D	A	-3.0548
186	Y	A	0.0000
187	E	A	-3.8321
188	K	A	-3.8591
189	H	A	-3.1290
190	K	A	-3.1512
191	V	A	-1.5241
192	Y	A	0.0000
193	A	A	0.0000
194	C	A	0.0000
195	E	A	-1.0085
196	V	A	0.0000
197	T	A	-1.2586
198	H	A	0.0000
199	Q	A	-1.6270
200	G	A	-0.4909
201	L	A	-0.2375
202	S	A	-0.4408
203	S	A	-0.4133
204	P	A	-0.6537
205	V	A	0.0122
206	T	A	-0.3547
207	K	A	-0.3469
208	S	A	-0.2858
209	F	A	-0.8826
210	N	A	-2.1510
211	R	A	-2.6981
212	G	A	-2.0554
213	E	A	-2.5494