| Chain sequence(s) |
A: KHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKP B: MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 267 | K | A | -3.0745 | |
| 268 | H | A | -3.0486 | |
| 269 | Q | A | -2.1257 | |
| 270 | P | A | -1.2505 | |
| 271 | G | A | -1.3004 | |
| 272 | G | A | -1.3549 | |
| 273 | G | A | -1.9158 | |
| 274 | K | A | -1.8266 | |
| 275 | V | A | 0.2026 | |
| 276 | Q | A | -0.0271 | |
| 277 | I | A | 1.7219 | |
| 278 | I | A | 1.5242 | |
| 279 | N | A | -0.4352 | |
| 280 | K | A | -1.5553 | |
| 281 | K | A | -1.2275 | |
| 282 | L | A | 0.3671 | |
| 283 | D | A | -0.4895 | |
| 284 | L | A | 0.5647 | |
| 285 | S | A | -0.9350 | |
| 286 | N | A | -1.0988 | |
| 287 | V | A | 0.8014 | |
| 288 | Q | A | -0.2190 | |
| 289 | S | A | -0.9246 | |
| 290 | K | A | -1.8846 | |
| 291 | C | A | -0.3507 | |
| 292 | G | A | 0.0000 | |
| 293 | S | A | -1.2385 | |
| 294 | K | A | -2.7718 | |
| 295 | D | A | -3.4144 | |
| 296 | N | A | -2.4215 | |
| 297 | I | A | -1.4225 | |
| 298 | K | A | -2.6197 | |
| 299 | H | A | -1.0862 | |
| 300 | V | A | 0.0000 | |
| 301 | P | A | -0.4460 | |
| 302 | G | A | 0.1356 | |
| 303 | G | A | -0.3442 | |
| 304 | G | A | -0.9209 | |
| 305 | S | A | -0.2474 | |
| 306 | V | A | 1.3856 | |
| 307 | Q | A | 0.1721 | |
| 308 | I | A | 1.1769 | |
| 309 | V | A | 0.8081 | |
| 310 | Y | A | 0.6538 | |
| 311 | K | A | -0.5142 | |
| 312 | P | A | -0.3031 | |
| 1 | M | B | -0.1811 | |
| 2 | A | B | -1.8375 | |
| 3 | D | B | -3.5280 | |
| 4 | E | B | -3.5467 | |
| 5 | E | B | -3.8634 | |
| 6 | K | B | -3.4084 | |
| 7 | L | B | -1.8925 | |
| 8 | P | B | -1.3641 | |
| 9 | P | B | -0.4216 | |
| 10 | G | B | -0.2972 | |
| 11 | W | B | -1.3273 | |
| 12 | E | B | -2.5386 | |
| 13 | K | B | -1.9570 | |
| 14 | R | B | -1.4300 | |
| 15 | M | B | 0.0887 | |
| 16 | S | B | -0.6153 | |
| 17 | R | B | -1.9195 | |
| 18 | S | B | -0.9523 | |
| 19 | S | B | -0.4052 | |
| 20 | G | B | -0.5549 | |
| 21 | R | B | -0.3532 | |
| 22 | V | B | 0.7257 | |
| 23 | Y | B | -0.2556 | |
| 24 | Y | B | -0.9311 | |
| 25 | F | B | -1.2781 | |
| 26 | N | B | -1.0189 | |
| 27 | H | B | -0.8311 | |
| 28 | I | B | 1.0946 | |
| 29 | T | B | -0.0402 | |
| 30 | N | B | -1.1400 | |
| 31 | A | B | -0.7902 | |
| 32 | S | B | -1.3535 | |
| 33 | Q | B | -0.9415 | |
| 34 | W | B | 0.0304 | |
| 35 | E | B | -1.1547 | |
| 36 | R | B | -2.6755 | |
| 37 | P | B | -1.9089 | |
| 38 | S | B | -2.1991 | |
| 39 | G | B | -3.0766 | |
| 40 | N | B | -2.5384 | |
| 41 | S | B | -1.3598 | |
| 42 | S | B | -1.0024 | |
| 43 | S | B | -1.1602 | |
| 44 | G | B | -2.0964 | |
| 45 | G | B | -2.1115 | |
| 46 | K | B | -2.9671 | |
| 47 | N | B | -3.1521 | |
| 48 | G | B | -2.5675 | |
| 49 | Q | B | -2.4372 | |
| 50 | G | B | -2.2037 | |
| 51 | E | B | -2.7361 | |
| 52 | P | B | -2.2622 | |
| 53 | A | B | -1.8598 | |
| 54 | R | B | -3.1373 | |
| 55 | V | B | 0.0000 | |
| 56 | R | B | -1.8544 | |
| 57 | C | B | 0.0000 | |
| 58 | S | B | 0.0000 | |
| 59 | H | B | 0.0000 | |
| 60 | L | B | 0.0000 | |
| 61 | L | B | 0.0000 | |
| 62 | V | B | 0.0000 | |
| 63 | K | B | 0.0000 | |
| 64 | H | B | 0.0000 | |
| 65 | S | B | -2.0274 | |
| 66 | Q | B | -2.3544 | |
| 67 | S | B | 0.0000 | |
| 68 | R | B | -3.5930 | |
| 69 | R | B | -3.7483 | |
| 70 | P | B | -2.9879 | |
| 71 | S | B | -2.6375 | |
| 72 | S | B | -1.3766 | |
| 73 | W | B | -0.0629 | |
| 74 | R | B | -1.6349 | |
| 75 | Q | B | -2.7687 | |
| 76 | E | B | -3.4845 | |
| 77 | K | B | -3.4868 | |
| 78 | I | B | 0.0000 | |
| 79 | T | B | -1.6960 | |
| 80 | R | B | -2.0669 | |
| 81 | T | B | -2.3670 | |
| 82 | K | B | -3.3143 | |
| 83 | E | B | -3.5681 | |
| 84 | E | B | -2.9084 | |
| 85 | A | B | 0.0000 | |
| 86 | L | B | -1.9420 | |
| 87 | E | B | -2.8562 | |
| 88 | L | B | -1.0744 | |
| 89 | I | B | 0.0000 | |
| 90 | N | B | -1.6136 | |
| 91 | G | B | -1.4523 | |
| 92 | Y | B | 0.0000 | |
| 93 | I | B | -1.7155 | |
| 94 | Q | B | -2.7801 | |
| 95 | K | B | -3.5011 | |
| 96 | I | B | 0.0000 | |
| 97 | K | B | -3.4216 | |
| 98 | S | B | -2.8837 | |
| 99 | G | B | -3.0955 | |
| 100 | E | B | -3.7449 | |
| 101 | E | B | -3.7711 | |
| 102 | D | B | -3.9084 | |
| 103 | F | B | 0.0000 | |
| 104 | E | B | -3.0970 | |
| 105 | S | B | -2.2268 | |
| 106 | L | B | 0.0000 | |
| 107 | A | B | 0.0000 | |
| 108 | S | B | -2.0141 | |
| 109 | Q | B | -1.5915 | |
| 110 | F | B | -0.4481 | |
| 111 | S | B | 0.0000 | |
| 112 | D | B | -0.4466 | |
| 113 | C | B | -0.2021 | |
| 114 | S | B | -0.5878 | |
| 115 | S | B | 0.0000 | |
| 116 | A | B | -1.7142 | |
| 117 | K | B | -2.0506 | |
| 118 | A | B | -1.7200 | |
| 119 | R | B | -2.6709 | |
| 120 | G | B | 0.0000 | |
| 121 | D | B | -1.2044 | |
| 122 | L | B | -0.2581 | |
| 123 | G | B | -0.7054 | |
| 124 | A | B | -1.3253 | |
| 125 | F | B | 0.0000 | |
| 126 | S | B | -2.3003 | |
| 127 | R | B | -3.3456 | |
| 128 | G | B | -2.8146 | |
| 129 | Q | B | -2.3965 | |
| 130 | M | B | -1.5729 | |
| 131 | Q | B | -2.1899 | |
| 132 | K | B | -2.8996 | |
| 133 | P | B | -1.3213 | |
| 134 | F | B | 0.0000 | |
| 135 | E | B | 0.0000 | |
| 136 | D | B | -2.4356 | |
| 137 | A | B | -1.1133 | |
| 138 | S | B | 0.0000 | |
| 139 | F | B | -1.0638 | |
| 140 | A | B | -0.6566 | |
| 141 | L | B | -1.0316 | |
| 142 | R | B | -2.3035 | |
| 143 | T | B | -1.9828 | |
| 144 | G | B | -1.8548 | |
| 145 | E | B | -1.9611 | |
| 146 | M | B | -0.8471 | |
| 147 | S | B | 0.0000 | |
| 148 | G | B | -0.0875 | |
| 149 | P | B | 0.1883 | |
| 150 | V | B | 0.8689 | |
| 151 | F | B | 1.4816 | |
| 152 | T | B | 0.0000 | |
| 153 | D | B | -2.3111 | |
| 154 | S | B | -1.7451 | |
| 155 | G | B | 0.0000 | |
| 156 | I | B | 0.0000 | |
| 157 | H | B | 0.0000 | |
| 158 | I | B | 0.0000 | |
| 159 | I | B | 0.0000 | |
| 160 | L | B | -0.9885 | |
| 161 | R | B | -1.5870 | |
| 162 | T | B | -1.8293 | |
| 163 | E | B | -2.8486 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine