Project name: 5t1k:A
Status: done
submitted: 2019-03-20 20:34:56, status changed: 2019-03-20 20:43:37
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.68
-
Maximal score value
-
1.9808
-
Average score
-
-0.796
-
Total score value
-
-169.5511
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.4092 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7489 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.3345 |
|
| 6 |
Q |
A |
0.0711 |
|
| 7 |
S |
A |
0.0600 |
|
| 8 |
P |
A |
0.8305 |
|
| 9 |
V |
A |
1.9808 |
|
| 10 |
I |
A |
1.5804 |
|
| 11 |
L |
A |
0.6606 |
|
| 12 |
S |
A |
-0.3956 |
|
| 13 |
V |
A |
0.0000 |
|
| 14 |
S |
A |
-1.8975 |
|
| 15 |
P |
A |
-2.0851 |
|
| 16 |
G |
A |
-2.1212 |
|
| 17 |
E |
A |
-2.8539 |
|
| 18 |
R |
A |
-3.1068 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.6885 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.9156 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.6622 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-1.0843 |
|
| 27 |
Q |
A |
-1.7194 |
|
| 28 |
S |
A |
-1.6290 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.1568 |
|
| 31 |
T |
A |
-0.8662 |
|
| 32 |
N |
A |
-1.0642 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.1554 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.4830 |
|
| 39 |
R |
A |
-2.0142 |
|
| 40 |
T |
A |
-1.8073 |
|
| 41 |
N |
A |
-1.9765 |
|
| 42 |
G |
A |
-1.6109 |
|
| 43 |
S |
A |
-1.1510 |
|
| 44 |
P |
A |
-1.0985 |
|
| 45 |
R |
A |
-1.0051 |
|
| 46 |
L |
A |
-0.1451 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.9030 |
|
| 50 |
Y |
A |
-0.4210 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.2416 |
|
| 53 |
E |
A |
-1.9852 |
|
| 54 |
S |
A |
-1.1381 |
|
| 55 |
I |
A |
-0.5005 |
|
| 56 |
S |
A |
-0.2540 |
|
| 57 |
G |
A |
-0.4421 |
|
| 58 |
I |
A |
-0.1898 |
|
| 59 |
P |
A |
-0.3113 |
|
| 60 |
S |
A |
-0.5284 |
|
| 61 |
R |
A |
-1.0389 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.8663 |
|
| 64 |
G |
A |
-0.7337 |
|
| 65 |
S |
A |
-0.8517 |
|
| 66 |
G |
A |
-1.1547 |
|
| 67 |
S |
A |
-1.2047 |
|
| 68 |
G |
A |
-1.4780 |
|
| 69 |
T |
A |
-2.1014 |
|
| 70 |
D |
A |
-2.8897 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9624 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.7996 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.0735 |
|
| 77 |
S |
A |
-2.1554 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.3415 |
|
| 80 |
S |
A |
-2.1004 |
|
| 81 |
E |
A |
-1.7121 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
-1.3293 |
|
| 84 |
A |
A |
-1.2603 |
|
| 85 |
D |
A |
-0.5435 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.2133 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.3375 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.3206 |
|
| 92 |
N |
A |
-1.6715 |
|
| 93 |
N |
A |
-1.2435 |
|
| 94 |
W |
A |
0.0916 |
|
| 95 |
P |
A |
-0.0966 |
|
| 96 |
T |
A |
-0.4073 |
|
| 97 |
T |
A |
0.3747 |
|
| 98 |
F |
A |
1.5269 |
|
| 99 |
G |
A |
0.6707 |
|
| 100 |
A |
A |
0.6448 |
|
| 101 |
G |
A |
0.4363 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.0355 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.0010 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.7637 |
|
| 108 |
R |
A |
-1.3584 |
|
| 109 |
T |
A |
-0.2090 |
|
| 110 |
V |
A |
0.2070 |
|
| 111 |
A |
A |
-0.1745 |
|
| 112 |
A |
A |
-0.2001 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
0.0364 |
|
| 115 |
V |
A |
0.5673 |
|
| 116 |
F |
A |
1.6407 |
|
| 117 |
I |
A |
1.4454 |
|
| 118 |
F |
A |
1.6297 |
|
| 119 |
P |
A |
0.0784 |
|
| 120 |
P |
A |
-0.7047 |
|
| 121 |
S |
A |
-1.7997 |
|
| 122 |
D |
A |
-3.2332 |
|
| 123 |
E |
A |
-3.4248 |
|
| 124 |
Q |
A |
-2.5136 |
|
| 125 |
L |
A |
-2.5667 |
|
| 126 |
K |
A |
-3.0015 |
|
| 127 |
S |
A |
-1.8678 |
|
| 128 |
G |
A |
-1.4479 |
|
| 129 |
T |
A |
-1.1478 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0341 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7366 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.6965 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.4598 |
|
| 138 |
N |
A |
-1.3100 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
-1.3100 |
|
| 141 |
P |
A |
-1.7927 |
|
| 142 |
R |
A |
-2.9290 |
|
| 143 |
E |
A |
-3.2099 |
|
| 144 |
A |
A |
-2.2511 |
|
| 145 |
K |
A |
-1.9004 |
|
| 146 |
V |
A |
-0.9710 |
|
| 147 |
Q |
A |
-0.5529 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.4877 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.7602 |
|
| 152 |
N |
A |
-1.4291 |
|
| 153 |
A |
A |
-0.2070 |
|
| 154 |
L |
A |
0.7577 |
|
| 155 |
Q |
A |
-0.1063 |
|
| 156 |
S |
A |
-0.4081 |
|
| 157 |
G |
A |
-1.0394 |
|
| 158 |
N |
A |
-1.0390 |
|
| 159 |
S |
A |
-1.4252 |
|
| 160 |
Q |
A |
-2.3129 |
|
| 161 |
E |
A |
-2.3289 |
|
| 162 |
S |
A |
-1.3414 |
|
| 163 |
V |
A |
-0.7524 |
|
| 164 |
T |
A |
-1.1600 |
|
| 165 |
E |
A |
-2.2658 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.2858 |
|
| 168 |
S |
A |
-2.2294 |
|
| 169 |
K |
A |
-2.7454 |
|
| 170 |
D |
A |
-2.3209 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-0.9617 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4367 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.6320 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.4235 |
|
| 181 |
L |
A |
-0.6875 |
|
| 182 |
S |
A |
-1.2746 |
|
| 183 |
K |
A |
-2.1489 |
|
| 184 |
A |
A |
-1.9464 |
|
| 185 |
D |
A |
-2.6982 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.5503 |
|
| 188 |
K |
A |
-3.6800 |
|
| 189 |
H |
A |
-2.9773 |
|
| 190 |
K |
A |
-2.9175 |
|
| 191 |
V |
A |
-1.2120 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
-0.7147 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.8183 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.1406 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.5964 |
|
| 200 |
G |
A |
-0.4436 |
|
| 201 |
L |
A |
-0.2152 |
|
| 202 |
S |
A |
-0.4416 |
|
| 203 |
S |
A |
-0.4187 |
|
| 204 |
P |
A |
-0.5317 |
|
| 205 |
V |
A |
-0.0028 |
|
| 206 |
T |
A |
-0.2756 |
|
| 207 |
K |
A |
-0.2208 |
|
| 208 |
S |
A |
-0.2157 |
|
| 209 |
F |
A |
-0.3836 |
|
| 210 |
N |
A |
-1.3560 |
|
| 211 |
R |
A |
-1.9694 |
|
| 212 |
G |
A |
-1.2155 |
|
| 213 |
A |
A |
-0.6320 |
|