Project name: 5i2i:B

Chain sequence(s)	B: QVQLKQSGPGLVQQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9025
• Maximal score value: 2.4212
• Average score: -0.5263
• Total score value: -115.7896

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4713
2	V	B	-0.8678
3	Q	B	-1.6259
4	L	B	0.0000
5	K	B	-2.2363
6	Q	B	0.0000
7	S	B	-0.7883
8	G	B	-0.9838
9	P	B	-0.4507
10	G	B	-0.4371
11	L	B	-0.0366
12	V	B	0.0000
13	Q	B	-1.3112
14	P	B	-1.3484
15	S	B	-1.6103
16	Q	B	-2.0898
17	S	B	-1.7912
18	L	B	0.0000
19	S	B	-0.6970
20	I	B	0.0000
21	T	B	-0.5775
22	C	B	0.0000
23	T	B	-1.2205
24	V	B	0.0000
25	S	B	-1.2734
26	G	B	-1.0112
27	F	B	-0.5536
28	S	B	-0.8726
29	L	B	0.0000
30	T	B	-0.8687
31	N	B	-0.8399
32	Y	B	0.4738
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.3492
40	S	B	-0.9672
41	P	B	-1.1284
42	G	B	-1.6763
43	K	B	-2.0318
44	G	B	-0.7188
45	L	B	0.7666
46	E	B	0.0000
47	W	B	0.5421
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.5870
53	S	B	-0.5867
54	G	B	-1.2045
55	G	B	-1.5121
56	N	B	-1.9934
57	T	B	-1.6118
58	D	B	-1.7167
59	Y	B	-0.7800
60	N	B	-0.6842
61	T	B	-0.5521
62	P	B	-0.4609
63	F	B	0.0000
64	T	B	-0.6292
65	S	B	-0.6189
66	R	B	-1.0416
67	L	B	0.0000
68	S	B	-1.0517
69	I	B	0.0000
70	N	B	-1.7681
71	K	B	-1.4810
72	D	B	-1.7590
73	N	B	-2.0986
74	S	B	-1.6282
75	K	B	-2.3275
76	S	B	-1.5198
77	Q	B	-1.5459
78	V	B	0.0000
79	F	B	-0.4669
80	F	B	0.0000
81	K	B	-1.4353
82	M	B	0.0000
83	N	B	-1.9591
84	S	B	-1.6607
85	L	B	0.0000
86	Q	B	-2.0714
87	S	B	-1.4668
88	N	B	-2.0605
89	D	B	0.0000
90	T	B	-0.6933
91	A	B	0.0000
92	I	B	0.5066
93	Y	B	0.0000
94	Y	B	-0.0921
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.8007
100	T	B	1.4166
101	Y	B	1.9641
102	Y	B	1.8212
103	D	B	0.8772
104	Y	B	0.8928
105	E	B	-0.0072
106	F	B	0.6234
107	A	B	0.7792
108	Y	B	0.5583
109	W	B	0.0711
110	G	B	0.0000
111	Q	B	-1.4699
112	G	B	-0.6307
113	T	B	0.0000
114	L	B	0.2060
115	V	B	0.0000
116	T	B	-0.3062
117	V	B	0.0000
118	S	B	-0.4606
119	A	B	-0.3667
120	A	B	-0.2621
121	S	B	-0.4746
122	T	B	-0.7332
123	K	B	-1.2365
124	G	B	-1.4191
125	P	B	0.0000
126	S	B	-0.0909
127	V	B	0.0000
128	F	B	0.9887
129	P	B	-0.1098
130	L	B	0.3532
131	A	B	-1.0848
132	P	B	0.0000
133	S	B	-1.4352
134	S	B	-1.1922
135	K	B	-1.9139
136	S	B	-1.0254
137	T	B	-1.0234
138	S	B	-0.9596
139	G	B	-0.8534
140	G	B	-0.9176
141	T	B	-0.6541
142	A	B	0.0000
143	A	B	-0.2057
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.6797
148	V	B	0.0000
149	K	B	-0.1907
150	D	B	-0.7065
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.1853
155	P	B	-0.6115
156	V	B	-0.6711
157	T	B	-0.6455
158	V	B	-0.2673
159	S	B	-0.4757
160	W	B	0.0000
161	N	B	-0.7451
162	S	B	-0.6340
163	G	B	-0.5563
164	A	B	-0.2349
165	L	B	-0.0231
166	T	B	-0.2878
167	S	B	-0.3049
168	G	B	-0.3287
169	V	B	-0.0815
170	H	B	-0.5835
171	T	B	0.0481
172	F	B	0.8546
173	P	B	0.6732
174	A	B	1.2577
175	V	B	2.4212
176	L	B	1.9960
177	Q	B	0.6187
178	S	B	0.0575
179	S	B	-0.2612
180	G	B	0.1679
181	L	B	0.2503
182	Y	B	0.8111
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6139
186	S	B	0.0000
187	V	B	0.3047
188	V	B	0.0000
189	T	B	-0.1980
190	V	B	0.0000
191	P	B	-0.6546
192	S	B	-0.6215
193	S	B	-0.6149
194	S	B	-0.6803
195	L	B	-0.8455
196	G	B	-0.9855
197	T	B	-0.7940
198	Q	B	-1.3700
199	T	B	-1.2231
200	Y	B	0.0000
201	I	B	-1.3935
202	C	B	0.0000
203	N	B	-1.4452
204	V	B	0.0000
205	N	B	-2.0747
206	H	B	0.0000
207	K	B	-2.7047
208	P	B	-1.5416
209	S	B	-1.7988
210	N	B	-2.5174
211	T	B	-2.0719
212	K	B	-2.6792
213	V	B	-1.5904
214	D	B	-2.2423
215	K	B	-1.9728
216	R	B	-2.5834
217	V	B	0.0000
218	E	B	-2.9025
219	P	B	-1.9102
220	K	B	-2.2426