Project name: HERGULIN

Chain sequence(s)	X: ELLPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELY
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.0409
• Maximal score value: 1.9707
• Average score: -0.9726
• Total score value: -201.3238

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	X	-0.7442
2	L	X	1.0611
3	L	X	1.5244
4	P	X	0.0000
5	P	X	0.0125
6	R	X	-0.5547
7	L	X	-0.0129
8	K	X	-2.0205
9	E	X	-2.7218
10	M	X	-2.2225
11	K	X	-2.4019
12	S	X	-2.1050
13	Q	X	-2.1191
14	E	X	-2.0536
15	S	X	-1.0435
16	A	X	-0.5217
17	A	X	-0.4333
18	G	X	-1.4806
19	S	X	-1.9026
20	K	X	-3.0737
21	L	X	0.0000
22	V	X	-1.1289
23	L	X	-0.6386
24	R	X	-2.0840
25	C	X	-1.9265
26	E	X	-2.0276
27	T	X	0.0000
28	S	X	-0.7753
29	S	X	-1.1774
30	E	X	-2.2080
31	Y	X	0.0000
32	S	X	-0.9958
33	S	X	-1.2450
34	L	X	0.0000
35	R	X	-2.5294
36	F	X	-1.5346
37	K	X	-1.1336
38	W	X	0.0000
39	F	X	0.0000
40	K	X	0.0000
41	N	X	-2.6750
42	G	X	-2.1993
43	N	X	-3.0681
44	E	X	-3.2982
45	L	X	-2.2602
46	N	X	-2.8486
47	R	X	-3.6061
48	K	X	-3.4071
49	N	X	-2.7923
50	K	X	0.0000
51	P	X	-2.2272
52	Q	X	-2.3931
53	N	X	-2.6427
54	I	X	-1.7038
55	K	X	-1.8648
56	I	X	-0.7221
57	Q	X	-2.2068
58	K	X	-3.2939
59	K	X	-3.3159
60	P	X	-2.4959
61	G	X	0.0000
62	K	X	-3.0147
63	S	X	0.0000
64	E	X	0.0000
65	L	X	0.0000
66	R	X	-2.3414
67	I	X	0.0000
68	N	X	-3.3353
69	K	X	-3.2977
70	A	X	0.0000
71	S	X	-0.4321
72	L	X	0.5833
73	A	X	0.3772
74	D	X	0.0000
75	S	X	-0.6870
76	G	X	-1.2736
77	E	X	-2.1847
78	Y	X	0.0000
79	M	X	-1.1255
80	C	X	0.0000
81	K	X	-0.9114
82	V	X	0.0000
83	I	X	-0.7314
84	S	X	-0.9889
85	K	X	-1.7664
86	L	X	-0.2244
87	G	X	0.1006
88	N	X	-0.4646
89	D	X	-0.1964
90	S	X	-0.4284
91	A	X	-0.6195
92	S	X	-1.0816
93	A	X	0.0000
94	N	X	-2.5523
95	I	X	0.0000
96	T	X	-0.9675
97	I	X	0.0000
98	V	X	0.6962
99	E	X	-0.1151
100	S	X	-0.6843
101	N	X	-1.5789
102	E	X	-1.7475
103	I	X	0.0364
104	I	X	0.4525
105	T	X	0.1053
106	G	X	-0.4268
107	M	X	-0.2147
108	P	X	-0.2033
109	A	X	-0.1071
110	S	X	0.0226
111	T	X	-0.5532
112	E	X	-1.7188
113	G	X	-1.1763
114	A	X	0.0390
115	Y	X	1.1899
116	V	X	0.4737
117	S	X	-0.7846
118	S	X	-1.8671
119	E	X	-2.2165
120	S	X	-1.3634
121	P	X	-1.5768
122	I	X	-1.2403
123	R	X	-2.0161
124	I	X	-0.5779
125	S	X	0.2243
126	V	X	0.0000
127	S	X	0.0000
128	T	X	-0.9164
129	E	X	-2.4508
130	G	X	-1.7932
131	A	X	-1.1562
132	N	X	-1.1192
133	T	X	-0.6808
134	S	X	0.0899
135	S	X	-0.6536
136	S	X	0.0000
137	T	X	0.0000
138	S	X	-0.8525
139	T	X	-0.6595
140	S	X	-0.7036
141	T	X	0.0000
142	T	X	-0.3983
143	G	X	-0.5124
144	T	X	-0.3897
145	S	X	-0.5920
146	H	X	-0.6992
147	L	X	-0.0527
148	V	X	-0.1126
149	K	X	-1.2720
150	C	X	0.0000
151	A	X	-1.6679
152	E	X	-2.7411
153	K	X	-2.8616
154	E	X	0.0000
155	K	X	-1.5258
156	T	X	-0.2933
157	F	X	1.9707
158	C	X	1.6911
159	V	X	0.9863
160	N	X	-1.0073
161	G	X	-0.8921
162	G	X	0.0000
163	E	X	0.6218
164	C	X	0.4499
165	F	X	0.0000
166	M	X	-0.7927
167	V	X	-0.5524
168	K	X	-2.3513
169	D	X	-2.4104
170	L	X	-1.7520
171	S	X	-1.1319
172	N	X	-0.9374
173	P	X	-0.6124
174	S	X	-0.1050
175	R	X	-0.3306
176	Y	X	-0.1503
177	L	X	0.2691
178	C	X	0.0000
179	K	X	-1.4601
180	C	X	0.0000
181	Q	X	-1.5983
182	P	X	-0.6855
183	G	X	-0.1395
184	F	X	1.3927
185	T	X	0.2346
186	G	X	-0.5736
187	A	X	-1.0279
188	R	X	-2.4242
189	C	X	-1.8676
190	T	X	-2.1053
191	E	X	-2.9858
192	N	X	-2.0244
193	V	X	-0.5445
194	P	X	-0.3513
195	M	X	-0.0396
196	K	X	-1.3927
197	V	X	0.1407
198	Q	X	-1.4172
199	N	X	-2.2427
200	Q	X	-3.0165
201	E	X	-4.0409
202	K	X	-3.5259
203	A	X	-1.9379
204	E	X	-1.8465
205	E	X	-1.6489
206	L	X	1.1841
207	Y	X	1.4042