Project name: 5xxy:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGFTFSDSWIHWVRQAPGKGLEWVAWISPYGGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARRHWPGGFDYWGQGTLVTVSAASTKGPSVFPLAPSSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7978
• Maximal score value: 2.512
• Average score: -0.5178
• Total score value: -107.7096

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.0848
2	V	H	-0.8905
3	Q	H	-1.2261
4	L	H	0.0000
5	V	H	0.5959
6	E	H	0.0000
7	S	H	-0.4771
8	G	H	-0.8020
9	G	H	-0.7248
10	G	H	-0.3944
11	L	H	-0.2090
12	V	H	0.0000
13	Q	H	-1.5653
14	P	H	-1.7997
15	G	H	-1.4686
16	G	H	-1.2435
17	S	H	-1.5936
18	L	H	-1.3283
19	R	H	-2.1795
20	L	H	0.0000
21	S	H	-0.3694
22	C	H	0.0000
23	A	H	-0.2207
24	A	H	0.0000
25	S	H	-0.7478
26	G	H	-1.0265
27	F	H	-0.5529
28	T	H	-0.6622
29	F	H	0.0000
30	S	H	-0.7024
31	D	H	-1.4902
32	S	H	0.0000
33	W	H	-0.0716
34	I	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.5264
40	A	H	-1.0620
41	P	H	-1.0583
42	G	H	-1.4058
43	K	H	-2.1035
44	G	H	-1.0162
45	L	H	0.3682
46	E	H	-0.6125
47	W	H	0.1164
48	V	H	0.0000
49	A	H	0.0000
50	W	H	0.6174
51	I	H	0.0000
52	S	H	-0.0126
53	P	H	0.0000
54	Y	H	0.4291
55	G	H	-0.1322
56	G	H	-0.2427
57	S	H	-0.0148
58	T	H	0.4294
59	Y	H	0.9142
60	Y	H	-0.2380
61	A	H	-1.1960
62	D	H	-2.3904
63	S	H	-1.5939
64	V	H	0.0000
65	K	H	-2.4667
66	G	H	-1.9129
67	R	H	-1.8326
68	F	H	0.0000
69	T	H	-0.8708
70	I	H	0.0000
71	S	H	-0.4352
72	A	H	-0.7230
73	D	H	-1.4812
74	T	H	-1.1837
75	S	H	-1.3316
76	K	H	-2.2348
77	N	H	-1.5658
78	T	H	0.0000
79	A	H	0.0000
80	Y	H	-0.5310
81	L	H	0.0000
82	Q	H	-1.5077
83	M	H	0.0000
84	N	H	-2.1007
85	S	H	-1.5214
86	L	H	0.0000
87	R	H	-2.5796
88	A	H	-1.7895
89	E	H	-2.2957
90	D	H	0.0000
91	T	H	-0.8232
92	A	H	0.0000
93	V	H	0.2947
94	Y	H	0.0000
95	Y	H	0.2840
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0151
99	R	H	-0.2758
100	H	H	-0.3430
101	W	H	0.5084
102	P	H	-0.1055
103	G	H	-0.4279
104	G	H	-0.5300
105	F	H	0.0049
106	D	H	-0.1884
107	Y	H	0.4260
108	W	H	0.5207
109	G	H	-0.0687
110	Q	H	-0.8610
111	G	H	-0.2766
112	T	H	-0.1481
113	L	H	0.0642
114	V	H	0.0000
115	T	H	-0.5034
116	V	H	0.0000
117	S	H	-0.7221
118	A	H	-0.4743
119	A	H	-0.4043
120	S	H	-0.6688
121	T	H	-1.0069
122	K	H	-1.8636
123	G	H	-1.7380
124	P	H	0.0000
125	S	H	-0.1887
126	V	H	0.0000
127	F	H	1.1868
128	P	H	0.2119
129	L	H	0.6683
130	A	H	-0.3529
131	P	H	-0.4665
132	S	H	-0.5306
133	S	H	-0.4365
140	T	H	-0.2786
141	A	H	-0.3066
142	A	H	0.0377
143	L	H	0.0000
144	G	H	0.0000
145	C	H	0.0000
146	L	H	0.7426
147	V	H	0.0000
148	K	H	-0.5069
149	D	H	-0.9379
150	Y	H	0.0000
151	F	H	0.0000
152	P	H	0.0000
153	E	H	-0.6126
154	P	H	-0.6726
155	V	H	-0.3515
156	T	H	-0.4629
157	V	H	-0.3277
158	S	H	-0.3938
159	W	H	0.0000
160	N	H	-0.8676
161	S	H	-0.7367
162	G	H	-0.6006
163	A	H	-0.2975
164	L	H	-0.0613
165	T	H	-0.3190
166	S	H	-0.3716
167	G	H	-0.4672
168	V	H	-0.0156
169	H	H	-0.5383
170	T	H	0.1151
171	F	H	0.7375
172	P	H	0.6385
173	A	H	1.1754
174	V	H	2.5120
175	L	H	2.0523
176	Q	H	0.6124
177	S	H	0.0395
178	S	H	-0.2820
179	G	H	-0.1363
180	L	H	0.0996
181	Y	H	0.6367
182	S	H	0.5453
183	L	H	0.0000
184	S	H	0.5670
185	S	H	0.0000
186	V	H	0.4105
187	V	H	0.0000
188	T	H	-0.2589
189	V	H	0.0000
190	P	H	-0.5939
191	S	H	-0.5367
192	S	H	-0.6071
197	Q	H	-1.4063
198	T	H	-1.1450
199	Y	H	-0.9638
200	I	H	-1.4675
201	C	H	0.0000
202	N	H	-1.5748
203	V	H	0.0000
204	N	H	-1.8073
205	H	H	0.0000
206	K	H	-2.7063
207	P	H	-1.7376
208	S	H	-1.9935
209	N	H	-2.6752
210	T	H	-2.1192
211	K	H	-2.7310
212	V	H	-1.6636
213	D	H	-2.7978
214	K	H	-2.4105
215	K	H	-2.5624
216	V	H	0.0000
217	E	H	-2.4643
218	P	H	-1.3149