Project name: mAb6

Chain sequence(s)	H: VQLVGSGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQVPGKGLEWVTMISYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAMYYCAKEGHISPFDYWGQGTLVTVS; L: EIVMTQSPATLSVSPGERATLSCRASQSVSSNLAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWLPWTFGQGTKVEIK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9219
• Maximal score value: 1.795
• Average score: -0.6434
• Total score value: -144.1228

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	L	-1.5924
2	I	L	0.0000
3	V	L	0.6833
4	M	L	0.0000
5	T	L	-0.7460
6	Q	L	-0.8892
7	S	L	-0.8298
8	P	L	-0.3392
9	A	L	-0.4222
10	T	L	-0.5651
11	L	L	-0.1453
12	S	L	-0.4177
13	V	L	-0.8457
14	S	L	-1.1393
15	P	L	-1.5964
16	G	L	-1.9494
17	E	L	-2.8651
18	R	L	-2.9219
19	A	L	0.0000
20	T	L	-0.5399
21	L	L	0.0000
22	S	L	-0.8234
23	C	L	0.0000
24	R	L	-2.2562
25	A	L	-1.1718
26	S	L	-0.8344
27	Q	L	-1.7100
28	S	L	-1.5727
29	V	L	0.0000
30	S	L	-0.8580
31	S	L	-0.7119
32	N	L	-0.6758
33	L	L	0.0000
34	A	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	-1.3420
39	K	L	-1.8553
40	P	L	-1.1465
41	G	L	-1.5249
42	Q	L	-2.2940
43	A	L	-1.6587
44	P	L	0.0000
45	R	L	-2.0050
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-0.2454
50	G	L	-0.3314
51	A	L	0.0000
52	S	L	-0.8336
53	T	L	-1.0241
54	R	L	-1.9740
55	A	L	-1.2819
56	T	L	-0.7990
57	G	L	-0.8217
58	I	L	0.0000
59	P	L	-0.6674
60	A	L	-0.6378
61	R	L	-0.8523
62	F	L	0.0000
63	S	L	-0.7740
64	G	L	-0.6945
65	S	L	-0.6200
66	G	L	-0.9565
67	S	L	-0.7545
68	G	L	-1.1696
69	T	L	-1.6358
70	E	L	-1.9157
71	F	L	0.0000
72	T	L	-0.6967
73	L	L	0.0000
74	T	L	-0.6208
75	I	L	0.0000
76	S	L	-1.5771
77	S	L	-1.6822
78	L	L	0.0000
79	Q	L	-1.8952
80	S	L	-1.2270
81	E	L	-2.1539
82	D	L	0.0000
83	F	L	-0.7572
84	A	L	0.0000
85	V	L	-0.4824
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	Q	L	0.0000
90	Q	L	0.0000
91	Y	L	0.0000
92	N	L	-1.1067
93	N	L	-1.4095
94	W	L	0.4519
95	L	L	0.2852
95A	P	L	-0.5381
96	W	L	0.0000
97	T	L	-0.3739
98	F	L	0.0000
99	G	L	0.0000
100	Q	L	-1.5514
101	G	L	-1.1309
102	T	L	0.0000
103	K	L	-0.8885
104	V	L	0.0000
105	E	L	-0.7250
106	I	L	0.5090
107	K	L	-1.0054
2	V	H	1.4974
3	Q	H	-0.0918
4	L	H	0.0000
5	V	H	-0.0582
6	G	H	-0.3356
7	S	H	-0.6026
8	G	H	-0.6757
9	G	H	-0.0688
10	G	H	0.7112
11	V	H	1.4356
12	V	H	0.0000
13	Q	H	-1.7719
14	P	H	-2.0670
15	G	H	-2.0765
16	R	H	-2.6914
17	S	H	-2.0473
18	L	H	-1.1828
19	R	H	-1.9868
20	L	H	0.0000
21	S	H	-0.5697
22	C	H	0.0000
23	A	H	-0.5606
24	A	H	-0.1810
25	S	H	0.3435
26	G	H	0.8411
27	F	H	1.7950
28	T	H	0.7603
29	F	H	0.0000
30	S	H	-0.2898
31	S	H	0.0044
32	Y	H	0.2007
33	G	H	-0.4376
34	M	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.6334
40	V	H	-0.9093
41	P	H	-0.7068
42	G	H	-1.3747
43	K	H	-2.3345
44	G	H	-1.6114
45	L	H	0.0000
46	E	H	-1.3384
47	W	H	0.0000
48	V	H	0.0000
49	T	H	0.0000
50	M	H	0.0000
51	I	H	0.0000
52	S	H	-0.7759
52A	Y	H	-0.0150
53	D	H	-1.8428
54	G	H	-1.8348
55	S	H	-1.5907
56	N	H	-2.1100
57	K	H	-2.0284
58	Y	H	-0.6353
59	Y	H	0.0000
60	A	H	-1.2893
61	D	H	-2.2508
62	S	H	-1.6353
63	V	H	0.0000
64	K	H	-2.6812
65	G	H	-1.8342
66	R	H	-2.0995
67	F	H	0.0000
68	T	H	-1.2696
69	I	H	0.0000
70	S	H	-0.9860
71	R	H	-1.1317
72	D	H	-1.9642
73	N	H	-1.9043
74	S	H	-1.8608
75	K	H	-2.3936
76	N	H	-1.5968
77	T	H	-0.9910
78	L	H	0.0000
79	Y	H	-0.3667
80	L	H	0.0000
81	Q	H	-1.2848
82	M	H	0.0000
82A	N	H	-2.0977
82B	S	H	-1.8342
82C	L	H	0.0000
83	R	H	-1.7506
84	A	H	-1.2943
85	E	H	-1.9115
86	D	H	0.0000
87	T	H	-0.2456
88	A	H	0.0000
89	M	H	0.4523
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	K	H	0.0000
95	E	H	-0.1079
96	G	H	-0.2402
97	H	H	-0.5426
98	I	H	0.6060
99	S	H	0.1187
100	P	H	0.0000
100A	F	H	0.0000
101	D	H	-0.3722
102	Y	H	0.2114
103	W	H	-0.2770
104	G	H	0.0000
105	Q	H	-1.6075
106	G	H	-0.6426
107	T	H	0.0249
108	L	H	1.0007
109	V	H	0.0000
110	T	H	0.2872
111	V	H	0.0000
112	S	H	-0.3861