Project name: retro9
Status: done
submitted: 2018-11-21 16:15:58, status changed: 2018-11-21 16:23:44
Settings
|
Chain sequence(s)
|
A: MEEPQSDLSTELPLSQETFSYLGKLLPEKLVLSPSLSPAAEAVDDLLLPEDAADWLESQAGAQGISEAPTLATSWTLSSSVPSQKTYPAPIVSVWASCILGQPSLSPTRTPLNLTCCFAGWQRPVQCSCGSPQHPRPAPVFTPWPSTRRQHMMEVVKHCPHLECRCDYSDCLDPPQHLIQ
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
-
-2.7514
-
Maximal score value
-
2.9909
-
Average score
-
-0.1848
-
Total score value
-
-33.2565
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
M |
A |
-1.4750 |
|
| 2 |
E |
A |
-2.6475 |
|
| 3 |
E |
A |
-2.7514 |
|
| 4 |
P |
A |
-1.7270 |
|
| 5 |
Q |
A |
-1.9486 |
|
| 6 |
S |
A |
-1.6827 |
|
| 7 |
D |
A |
-1.7274 |
|
| 8 |
L |
A |
0.0050 |
|
| 9 |
S |
A |
0.0231 |
|
| 10 |
T |
A |
-0.3911 |
|
| 11 |
E |
A |
-1.8845 |
|
| 12 |
L |
A |
-0.5782 |
|
| 13 |
P |
A |
-0.2868 |
|
| 14 |
L |
A |
0.2927 |
|
| 15 |
S |
A |
-0.0322 |
|
| 16 |
Q |
A |
-0.0804 |
|
| 17 |
E |
A |
-0.2182 |
|
| 18 |
T |
A |
0.0937 |
|
| 19 |
F |
A |
0.6542 |
|
| 20 |
S |
A |
0.7203 |
|
| 21 |
Y |
A |
0.0000 |
|
| 22 |
L |
A |
1.4563 |
|
| 23 |
G |
A |
-0.1645 |
|
| 24 |
K |
A |
-1.4116 |
|
| 25 |
L |
A |
0.5513 |
|
| 26 |
L |
A |
0.0000 |
|
| 27 |
P |
A |
-1.6591 |
|
| 28 |
E |
A |
-2.0741 |
|
| 29 |
K |
A |
-1.1023 |
|
| 30 |
L |
A |
0.2167 |
|
| 31 |
V |
A |
0.5651 |
|
| 32 |
L |
A |
0.6953 |
|
| 33 |
S |
A |
0.4512 |
|
| 34 |
P |
A |
0.1518 |
|
| 35 |
S |
A |
-0.0775 |
|
| 36 |
L |
A |
0.0938 |
|
| 37 |
S |
A |
-0.4191 |
|
| 38 |
P |
A |
-0.0289 |
|
| 39 |
A |
A |
0.4035 |
|
| 40 |
A |
A |
0.4194 |
|
| 41 |
E |
A |
0.6236 |
|
| 42 |
A |
A |
0.6390 |
|
| 43 |
V |
A |
1.4775 |
|
| 44 |
D |
A |
-0.1422 |
|
| 45 |
D |
A |
0.0000 |
|
| 46 |
L |
A |
0.8889 |
|
| 47 |
L |
A |
1.5400 |
|
| 48 |
L |
A |
0.8761 |
|
| 49 |
P |
A |
0.0000 |
|
| 50 |
E |
A |
0.0573 |
|
| 51 |
D |
A |
-0.3924 |
|
| 52 |
A |
A |
0.0000 |
|
| 53 |
A |
A |
-0.6301 |
|
| 54 |
D |
A |
-0.1100 |
|
| 55 |
W |
A |
0.0000 |
|
| 56 |
L |
A |
-0.0153 |
|
| 57 |
E |
A |
-0.6705 |
|
| 58 |
S |
A |
-1.2576 |
|
| 59 |
Q |
A |
-1.3590 |
|
| 60 |
A |
A |
-0.5280 |
|
| 61 |
G |
A |
0.0670 |
|
| 62 |
A |
A |
-0.0059 |
|
| 63 |
Q |
A |
-0.1365 |
|
| 64 |
G |
A |
0.0000 |
|
| 65 |
I |
A |
0.7040 |
|
| 66 |
S |
A |
-0.1492 |
|
| 67 |
E |
A |
-1.5039 |
|
| 68 |
A |
A |
-0.5375 |
|
| 69 |
P |
A |
-0.0371 |
|
| 70 |
T |
A |
0.5217 |
|
| 71 |
L |
A |
1.5157 |
|
| 72 |
A |
A |
0.4345 |
|
| 73 |
T |
A |
-0.4878 |
|
| 74 |
S |
A |
-0.1351 |
|
| 75 |
W |
A |
-0.2237 |
|
| 76 |
T |
A |
0.0000 |
|
| 77 |
L |
A |
0.0864 |
|
| 78 |
S |
A |
-0.0486 |
|
| 79 |
S |
A |
0.0000 |
|
| 80 |
S |
A |
0.0000 |
|
| 81 |
V |
A |
0.0000 |
|
| 82 |
P |
A |
-0.7315 |
|
| 83 |
S |
A |
-0.8798 |
|
| 84 |
Q |
A |
-1.4112 |
|
| 85 |
K |
A |
-2.3488 |
|
| 86 |
T |
A |
-0.8324 |
|
| 87 |
Y |
A |
0.4440 |
|
| 88 |
P |
A |
0.9396 |
|
| 89 |
A |
A |
0.9774 |
|
| 90 |
P |
A |
1.0207 |
|
| 91 |
I |
A |
2.9052 |
|
| 92 |
V |
A |
2.9909 |
|
| 93 |
S |
A |
1.9141 |
|
| 94 |
V |
A |
2.0775 |
|
| 95 |
W |
A |
0.0000 |
|
| 96 |
A |
A |
0.9149 |
|
| 97 |
S |
A |
0.3105 |
|
| 98 |
C |
A |
1.2513 |
|
| 99 |
I |
A |
1.8108 |
|
| 100 |
L |
A |
0.0000 |
|
| 101 |
G |
A |
-0.2737 |
|
| 102 |
Q |
A |
-0.7520 |
|
| 103 |
P |
A |
-0.6572 |
|
| 104 |
S |
A |
-0.3934 |
|
| 105 |
L |
A |
0.0000 |
|
| 106 |
S |
A |
-0.3584 |
|
| 107 |
P |
A |
-0.0054 |
|
| 108 |
T |
A |
-0.5946 |
|
| 109 |
R |
A |
-0.9219 |
|
| 110 |
T |
A |
0.0007 |
|
| 111 |
P |
A |
0.4843 |
|
| 112 |
L |
A |
1.4261 |
|
| 113 |
N |
A |
0.6472 |
|
| 114 |
L |
A |
1.3859 |
|
| 115 |
T |
A |
0.4709 |
|
| 116 |
C |
A |
1.0102 |
|
| 117 |
C |
A |
0.9605 |
|
| 118 |
F |
A |
1.7962 |
|
| 119 |
A |
A |
0.4441 |
|
| 120 |
G |
A |
-0.6158 |
|
| 121 |
W |
A |
-1.0996 |
|
| 122 |
Q |
A |
-1.9515 |
|
| 123 |
R |
A |
-2.2222 |
|
| 124 |
P |
A |
-0.4692 |
|
| 125 |
V |
A |
1.0332 |
|
| 126 |
Q |
A |
0.4063 |
|
| 127 |
C |
A |
0.4404 |
|
| 128 |
S |
A |
-0.0205 |
|
| 129 |
C |
A |
0.0117 |
|
| 130 |
G |
A |
-0.8823 |
|
| 131 |
S |
A |
-0.9413 |
|
| 132 |
P |
A |
-1.3479 |
|
| 133 |
Q |
A |
-2.3398 |
|
| 134 |
H |
A |
-2.4187 |
|
| 135 |
P |
A |
-1.9404 |
|
| 136 |
R |
A |
-1.3484 |
|
| 137 |
P |
A |
-0.7099 |
|
| 138 |
A |
A |
-0.2510 |
|
| 139 |
P |
A |
-0.6618 |
|
| 140 |
V |
A |
0.0000 |
|
| 141 |
F |
A |
0.0000 |
|
| 142 |
T |
A |
0.0000 |
|
| 143 |
P |
A |
0.0000 |
|
| 144 |
W |
A |
0.0000 |
|
| 145 |
P |
A |
0.0000 |
|
| 146 |
S |
A |
0.0000 |
|
| 147 |
T |
A |
-0.9691 |
|
| 148 |
R |
A |
-1.8984 |
|
| 149 |
R |
A |
0.0000 |
|
| 150 |
Q |
A |
-1.5752 |
|
| 151 |
H |
A |
-0.8039 |
|
| 152 |
M |
A |
0.2258 |
|
| 153 |
M |
A |
0.0000 |
|
| 154 |
E |
A |
-0.3036 |
|
| 155 |
V |
A |
0.0000 |
|
| 156 |
V |
A |
0.0781 |
|
| 157 |
K |
A |
0.0000 |
|
| 158 |
H |
A |
-0.3187 |
|
| 159 |
C |
A |
0.0000 |
|
| 160 |
P |
A |
-0.6588 |
|
| 161 |
H |
A |
-0.7771 |
|
| 162 |
L |
A |
-0.7616 |
|
| 163 |
E |
A |
0.0000 |
|
| 164 |
C |
A |
0.0155 |
|
| 165 |
R |
A |
0.0000 |
|
| 166 |
C |
A |
-0.7648 |
|
| 167 |
D |
A |
-1.6467 |
|
| 168 |
Y |
A |
-0.3870 |
|
| 169 |
S |
A |
-0.8019 |
|
| 170 |
D |
A |
-1.4620 |
|
| 171 |
C |
A |
-0.1208 |
|
| 172 |
L |
A |
0.6952 |
|
| 173 |
D |
A |
-0.2778 |
|
| 174 |
P |
A |
-0.6964 |
|
| 175 |
P |
A |
-1.1466 |
|
| 176 |
Q |
A |
-1.7413 |
|
| 177 |
H |
A |
-1.1050 |
|
| 178 |
L |
A |
0.7193 |
|
| 179 |
I |
A |
1.1978 |
|
| 180 |
Q |
A |
-0.1521 |
|