| Chain sequence(s) |
A: KHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKP B: MQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQS |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 267 | K | A | -3.2123 | |
| 268 | H | A | -3.1257 | |
| 269 | Q | A | -2.5633 | |
| 270 | P | A | -1.5573 | |
| 271 | G | A | -1.6016 | |
| 272 | G | A | -1.5646 | |
| 273 | G | A | -2.0389 | |
| 274 | K | A | -1.7712 | |
| 275 | V | A | -0.3527 | |
| 276 | Q | A | -0.8489 | |
| 277 | I | A | -0.3535 | |
| 278 | I | A | 0.3828 | |
| 279 | N | A | -0.4760 | |
| 280 | K | A | -1.7521 | |
| 281 | K | A | -1.5876 | |
| 282 | L | A | -0.2535 | |
| 283 | D | A | -0.6994 | |
| 284 | L | A | 0.5273 | |
| 285 | S | A | -0.9610 | |
| 286 | N | A | -1.1499 | |
| 287 | V | A | 0.7963 | |
| 288 | Q | A | -0.1787 | |
| 289 | S | A | -0.9814 | |
| 290 | K | A | -1.8012 | |
| 291 | C | A | -0.2533 | |
| 292 | G | A | 0.0000 | |
| 293 | S | A | -0.8785 | |
| 294 | K | A | -2.4983 | |
| 295 | D | A | -3.0706 | |
| 296 | N | A | -1.8767 | |
| 297 | I | A | -0.5227 | |
| 298 | K | A | -2.3188 | |
| 299 | H | A | -0.9596 | |
| 300 | V | A | 0.0000 | |
| 301 | P | A | -0.3164 | |
| 302 | G | A | 0.4097 | |
| 303 | G | A | -0.1665 | |
| 304 | G | A | -0.8731 | |
| 305 | S | A | -0.1617 | |
| 306 | V | A | 1.4468 | |
| 307 | Q | A | -0.0089 | |
| 308 | I | A | 0.3799 | |
| 309 | V | A | 1.4368 | |
| 310 | Y | A | 0.0152 | |
| 311 | K | A | -1.4068 | |
| 312 | P | A | -1.0297 | |
| 79 | M | B | 0.9118 | |
| 80 | Q | B | -0.0880 | |
| 81 | L | B | 1.0548 | |
| 82 | S | B | 0.4108 | |
| 83 | S | B | 0.0692 | |
| 84 | G | B | 0.0582 | |
| 85 | V | B | 1.0959 | |
| 86 | S | B | 0.0331 | |
| 87 | E | B | -1.1707 | |
| 88 | I | B | 0.1284 | |
| 89 | R | B | -1.9231 | |
| 90 | H | B | -2.0829 | |
| 91 | T | B | -1.6529 | |
| 92 | A | B | -2.0889 | |
| 93 | D | B | -2.8099 | |
| 94 | R | B | -2.8315 | |
| 95 | W | B | -1.0570 | |
| 96 | R | B | -1.8449 | |
| 97 | V | B | -0.4381 | |
| 98 | S | B | -0.7638 | |
| 99 | L | B | 0.0000 | |
| 100 | D | B | -1.8451 | |
| 101 | V | B | -1.2187 | |
| 102 | N | B | 0.0000 | |
| 103 | H | B | -1.7970 | |
| 104 | F | B | -1.2929 | |
| 105 | A | B | 0.0000 | |
| 106 | P | B | -1.9930 | |
| 107 | D | B | -2.9569 | |
| 108 | E | B | -3.3116 | |
| 109 | L | B | -1.4401 | |
| 110 | T | B | -1.0169 | |
| 111 | V | B | 0.1648 | |
| 112 | K | B | -1.5333 | |
| 113 | T | B | -1.6083 | |
| 114 | K | B | -2.2539 | |
| 115 | D | B | -2.5432 | |
| 116 | G | B | 0.0000 | |
| 117 | V | B | -1.3800 | |
| 118 | V | B | 0.0000 | |
| 119 | E | B | 0.0000 | |
| 120 | I | B | 0.0000 | |
| 121 | T | B | -1.1519 | |
| 122 | G | B | 0.0000 | |
| 123 | K | B | -2.5581 | |
| 124 | H | B | -2.8979 | |
| 125 | E | B | -3.6848 | |
| 126 | E | B | -3.6507 | |
| 127 | R | B | -3.3036 | |
| 128 | Q | B | -3.0318 | |
| 129 | D | B | -3.0002 | |
| 130 | E | B | -2.9955 | |
| 131 | H | B | -1.9133 | |
| 132 | G | B | 0.0000 | |
| 133 | Y | B | -1.2114 | |
| 134 | I | B | -1.1020 | |
| 135 | S | B | -1.9691 | |
| 136 | R | B | -1.7099 | |
| 137 | C | B | -0.8727 | |
| 138 | F | B | -0.3158 | |
| 139 | T | B | -1.1280 | |
| 140 | R | B | -1.6975 | |
| 141 | K | B | -1.9957 | |
| 142 | Y | B | -0.5530 | |
| 143 | T | B | -0.5298 | |
| 144 | L | B | 0.0470 | |
| 145 | P | B | -0.3262 | |
| 146 | P | B | -0.2283 | |
| 147 | G | B | -0.0996 | |
| 148 | V | B | 0.0000 | |
| 149 | D | B | -1.4140 | |
| 150 | P | B | -1.5232 | |
| 151 | T | B | -1.1994 | |
| 152 | Q | B | -1.4252 | |
| 153 | V | B | -0.8678 | |
| 154 | S | B | -0.6471 | |
| 155 | S | B | -0.1463 | |
| 156 | S | B | 0.3208 | |
| 157 | L | B | 0.6734 | |
| 158 | S | B | -0.5615 | |
| 159 | P | B | -1.2972 | |
| 160 | E | B | -2.2192 | |
| 161 | G | B | 0.0000 | |
| 162 | T | B | -1.2127 | |
| 163 | L | B | 0.0000 | |
| 164 | T | B | -0.4749 | |
| 165 | V | B | 0.0000 | |
| 166 | E | B | -1.4364 | |
| 167 | A | B | 0.0000 | |
| 168 | P | B | -1.8284 | |
| 169 | M | B | -1.0463 | |
| 170 | P | B | -0.5987 | |
| 171 | K | B | -1.0633 | |
| 172 | L | B | 0.4348 | |
| 173 | A | B | 0.0461 | |
| 174 | T | B | -0.5139 | |
| 175 | Q | B | -1.0974 | |
| 176 | S | B | -0.8066 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine