| Chain sequence(s) |
A: MNALLSNPFKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDNLDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKS C: MNALLSNPFKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDNLDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKS B: MNALLSNPFKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDNLDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKS |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
| Mutated residues | VA218R, FA254E |
| Energy difference between WT (input) and mutated protein (by FoldX) | 0.958428 kcal/mol
Changes in protein stability upon mutation are calculated using the FoldX forcefield. Computational prediction of protein stability is used with the intention of preventing the experimental characterization of proteins bearing mutations that significantly destabilize their structure. Mutations resulting in a predicted reduction in protein stability ≥ 1 kcal/mol are considered disruptive. |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | M | A | 0.3861 | |
| 2 | N | A | -0.7026 | |
| 3 | A | A | -0.6887 | |
| 4 | L | A | 0.6600 | |
| 5 | L | A | -0.1530 | |
| 6 | S | A | -0.3055 | |
| 7 | N | A | 0.0000 | |
| 8 | P | A | -1.0900 | |
| 9 | F | A | 0.0000 | |
| 10 | K | A | 0.0000 | |
| 11 | E | A | -2.9976 | |
| 12 | R | A | -3.0956 | |
| 13 | L | A | 0.0000 | |
| 14 | R | A | -3.7766 | |
| 15 | K | A | -3.5863 | |
| 16 | G | A | -2.6268 | |
| 17 | E | A | -2.2332 | |
| 18 | V | A | -0.0013 | |
| 19 | Q | A | 0.0000 | |
| 20 | I | A | 0.4258 | |
| 21 | G | A | 0.0000 | |
| 22 | L | A | 0.0000 | |
| 23 | W | A | 0.0000 | |
| 24 | L | A | 0.0000 | |
| 25 | S | A | 0.0000 | |
| 26 | S | A | 0.0764 | |
| 27 | T | A | 0.0000 | |
| 28 | T | A | 0.1227 | |
| 29 | A | A | 0.1363 | |
| 30 | Y | A | 1.2337 | |
| 31 | M | A | 0.8620 | |
| 32 | A | A | 0.0000 | |
| 33 | E | A | -0.2126 | |
| 34 | I | A | 0.8253 | |
| 35 | A | A | 0.0000 | |
| 36 | A | A | 0.0000 | |
| 37 | T | A | -0.1040 | |
| 38 | S | A | -0.3754 | |
| 39 | G | A | -0.5859 | |
| 40 | Y | A | -0.3152 | |
| 41 | D | A | -0.8608 | |
| 42 | W | A | 0.0000 | |
| 43 | L | A | 0.0000 | |
| 44 | L | A | 0.0000 | |
| 45 | I | A | 0.0000 | |
| 46 | D | A | 0.0000 | |
| 47 | G | A | 0.0000 | |
| 48 | E | A | 0.0000 | |
| 49 | H | A | 0.0000 | |
| 50 | A | A | 0.0000 | |
| 51 | P | A | 0.0016 | |
| 52 | N | A | 0.0000 | |
| 53 | T | A | -0.0762 | |
| 54 | I | A | 0.0297 | |
| 55 | Q | A | -0.4156 | |
| 56 | D | A | -0.6713 | |
| 57 | L | A | 0.0000 | |
| 58 | Y | A | -0.5777 | |
| 59 | H | A | -1.1047 | |
| 60 | Q | A | 0.0000 | |
| 61 | L | A | 0.0000 | |
| 62 | Q | A | -1.3725 | |
| 63 | A | A | -0.5418 | |
| 64 | V | A | 0.0000 | |
| 65 | A | A | -0.4774 | |
| 66 | P | A | -0.2858 | |
| 67 | Y | A | 0.0775 | |
| 68 | A | A | -0.1194 | |
| 69 | S | A | 0.0000 | |
| 70 | Q | A | -0.3980 | |
| 71 | P | A | -0.2058 | |
| 72 | V | A | 0.0000 | |
| 73 | I | A | 0.0000 | |
| 74 | R | A | 0.0000 | |
| 75 | P | A | 0.0000 | |
| 76 | V | A | 0.1613 | |
| 77 | E | A | -0.3042 | |
| 78 | G | A | -0.4429 | |
| 79 | S | A | -0.5466 | |
| 80 | K | A | -1.0567 | |
| 81 | P | A | -0.2088 | |
| 82 | L | A | 0.1930 | |
| 83 | I | A | 0.0000 | |
| 84 | K | A | 0.0000 | |
| 85 | Q | A | 0.0000 | |
| 86 | V | A | 0.0000 | |
| 87 | L | A | 0.0000 | |
| 88 | D | A | 0.0000 | |
| 89 | I | A | 0.0000 | |
| 90 | G | A | -0.2641 | |
| 91 | A | A | 0.0000 | |
| 92 | Q | A | -0.3093 | |
| 93 | T | A | 0.0000 | |
| 94 | L | A | 0.0000 | |
| 95 | L | A | 0.0000 | |
| 96 | I | A | 0.0000 | |
| 97 | P | A | 0.0000 | |
| 98 | M | A | 0.1508 | |
| 99 | V | A | 0.0000 | |
| 100 | D | A | -1.1714 | |
| 101 | T | A | -2.1240 | |
| 102 | A | A | 0.0000 | |
| 103 | E | A | -3.3430 | |
| 104 | Q | A | -2.5268 | |
| 105 | A | A | 0.0000 | |
| 106 | R | A | -3.7724 | |
| 107 | Q | A | -3.0957 | |
| 108 | V | A | 0.0000 | |
| 109 | V | A | -1.9989 | |
| 110 | S | A | -1.7832 | |
| 111 | A | A | 0.0000 | |
| 112 | T | A | -1.3832 | |
| 113 | R | A | -1.5438 | |
| 114 | Y | A | 0.0000 | |
| 115 | P | A | -0.6535 | |
| 116 | P | A | -0.1987 | |
| 117 | Y | A | 0.5103 | |
| 118 | G | A | -1.1725 | |
| 119 | E | A | -2.1338 | |
| 120 | R | A | 0.0000 | |
| 121 | G | A | -0.7429 | |
| 122 | V | A | -0.4362 | |
| 123 | G | A | -0.0970 | |
| 124 | A | A | 0.0000 | |
| 125 | S | A | -0.8231 | |
| 126 | V | A | 0.0807 | |
| 127 | A | A | 0.0000 | |
| 128 | R | A | 0.0000 | |
| 129 | A | A | 0.0000 | |
| 130 | A | A | 0.0000 | |
| 131 | R | A | -1.0051 | |
| 132 | W | A | -0.4757 | |
| 133 | G | A | -1.7531 | |
| 134 | R | A | -1.5759 | |
| 135 | I | A | 0.0000 | |
| 136 | E | A | -2.8326 | |
| 137 | N | A | -2.5517 | |
| 138 | Y | A | 0.0000 | |
| 139 | M | A | -1.2230 | |
| 140 | A | A | -1.2540 | |
| 141 | Q | A | -1.1932 | |
| 142 | V | A | 0.0000 | |
| 143 | N | A | -2.4027 | |
| 144 | D | A | -2.5514 | |
| 145 | S | A | 0.0000 | |
| 146 | L | A | -1.0712 | |
| 147 | C | A | 0.0000 | |
| 148 | L | A | 0.0000 | |
| 149 | L | A | 0.0000 | |
| 150 | V | A | 0.0000 | |
| 151 | Q | A | 0.0000 | |
| 152 | V | A | 0.0000 | |
| 153 | E | A | -0.5367 | |
| 154 | S | A | -1.3937 | |
| 155 | K | A | -2.2366 | |
| 156 | T | A | -1.5801 | |
| 157 | A | A | 0.0000 | |
| 158 | L | A | -1.7549 | |
| 159 | D | A | -2.8324 | |
| 160 | N | A | -2.4819 | |
| 161 | L | A | 0.0000 | |
| 162 | D | A | -3.7532 | |
| 163 | E | A | -3.8158 | |
| 164 | I | A | 0.0000 | |
| 165 | L | A | 0.0000 | |
| 166 | D | A | -3.5791 | |
| 167 | V | A | 0.0000 | |
| 168 | E | A | -2.8135 | |
| 169 | G | A | -2.3003 | |
| 170 | I | A | 0.0000 | |
| 171 | D | A | -1.0494 | |
| 172 | G | A | 0.0000 | |
| 173 | V | A | 0.0000 | |
| 174 | F | A | 0.0000 | |
| 175 | I | A | 0.0000 | |
| 176 | G | A | -0.1123 | |
| 177 | P | A | -0.1660 | |
| 178 | A | A | -0.3626 | |
| 179 | D | A | -0.7492 | |
| 180 | L | A | 0.0000 | |
| 181 | S | A | 0.0000 | |
| 182 | A | A | 0.0000 | |
| 183 | S | A | -0.9788 | |
| 184 | L | A | -0.6513 | |
| 185 | G | A | -1.0695 | |
| 186 | Y | A | -1.3176 | |
| 187 | P | A | -1.2628 | |
| 188 | D | A | -2.6898 | |
| 189 | N | A | -2.2924 | |
| 190 | A | A | -1.5529 | |
| 191 | G | A | -1.6529 | |
| 192 | H | A | -2.3651 | |
| 193 | P | A | -2.1415 | |
| 194 | E | A | -2.5958 | |
| 195 | V | A | 0.0000 | |
| 196 | Q | A | -2.5640 | |
| 197 | R | A | -3.0003 | |
| 198 | I | A | -1.7140 | |
| 199 | I | A | 0.0000 | |
| 200 | E | A | -2.3543 | |
| 201 | T | A | -2.0886 | |
| 202 | S | A | 0.0000 | |
| 203 | I | A | 0.0000 | |
| 204 | R | A | -3.1800 | |
| 205 | R | A | -3.5017 | |
| 206 | I | A | 0.0000 | |
| 207 | R | A | -2.2727 | |
| 208 | A | A | -1.7150 | |
| 209 | A | A | -1.8314 | |
| 210 | G | A | -1.3948 | |
| 211 | K | A | -1.5895 | |
| 212 | A | A | 0.0000 | |
| 213 | A | A | 0.0000 | |
| 214 | G | A | 0.0000 | |
| 215 | F | A | 0.0000 | |
| 216 | L | A | -0.0098 | |
| 217 | A | A | 0.0000 | |
| 218 | R | A | -1.2356 | mutated: VA218R |
| 219 | A | A | -1.2888 | |
| 220 | P | A | -1.6974 | |
| 221 | D | A | -2.4536 | |
| 222 | M | A | -1.5320 | |
| 223 | A | A | 0.0000 | |
| 224 | Q | A | -1.8385 | |
| 225 | Q | A | -1.5139 | |
| 226 | C | A | 0.0000 | |
| 227 | L | A | -0.1024 | |
| 228 | A | A | -0.2844 | |
| 229 | W | A | -0.7845 | |
| 230 | G | A | -0.7529 | |
| 231 | A | A | 0.0000 | |
| 232 | N | A | 0.0000 | |
| 233 | F | A | 0.0000 | |
| 234 | V | A | 0.0000 | |
| 235 | A | A | 0.0000 | |
| 236 | V | A | -0.1901 | |
| 237 | G | A | -0.0326 | |
| 238 | V | A | 0.0000 | |
| 239 | D | A | 0.0000 | |
| 240 | T | A | 0.3384 | |
| 241 | M | A | 0.2854 | |
| 242 | L | A | 0.6944 | |
| 243 | Y | A | 0.5193 | |
| 244 | S | A | -0.4359 | |
| 245 | D | A | -1.4545 | |
| 246 | A | A | -0.5770 | |
| 247 | L | A | 0.3428 | |
| 248 | D | A | -0.8598 | |
| 249 | Q | A | -1.8510 | |
| 250 | R | A | -1.8093 | |
| 251 | L | A | -0.3687 | |
| 252 | A | A | -0.8996 | |
| 253 | M | A | -0.7165 | |
| 254 | E | A | -2.1453 | mutated: FA254E |
| 255 | K | A | -2.1967 | |
| 256 | S | A | -1.0058 | |
| 1 | M | B | 0.3920 | |
| 2 | N | B | -0.6959 | |
| 3 | A | B | -0.7025 | |
| 4 | L | B | 0.6291 | |
| 5 | L | B | -0.0559 | |
| 6 | S | B | -0.3221 | |
| 7 | N | B | 0.0000 | |
| 8 | P | B | -0.9514 | |
| 9 | F | B | 0.0000 | |
| 10 | K | B | 0.0000 | |
| 11 | E | B | -2.8456 | |
| 12 | R | B | -2.4511 | |
| 13 | L | B | 0.0000 | |
| 14 | R | B | -3.6839 | |
| 15 | K | B | -3.3357 | |
| 16 | G | B | -2.3312 | |
| 17 | E | B | -1.7424 | |
| 18 | V | B | 0.8314 | |
| 19 | Q | B | 0.0000 | |
| 20 | I | B | 0.8518 | |
| 21 | G | B | 0.0000 | |
| 22 | L | B | 0.0000 | |
| 23 | W | B | 0.0000 | |
| 24 | L | B | 0.0000 | |
| 25 | S | B | 0.0000 | |
| 26 | S | B | 0.1211 | |
| 27 | T | B | -0.1069 | |
| 28 | T | B | 0.0734 | |
| 29 | A | B | 0.0120 | |
| 30 | Y | B | 1.1779 | |
| 31 | M | B | 0.8194 | |
| 32 | A | B | 0.0000 | |
| 33 | E | B | -0.3487 | |
| 34 | I | B | 0.7519 | |
| 35 | A | B | 0.0000 | |
| 36 | A | B | 0.0000 | |
| 37 | T | B | -0.1334 | |
| 38 | S | B | -0.3479 | |
| 39 | G | B | -0.4739 | |
| 40 | Y | B | -0.1031 | |
| 41 | D | B | -0.2889 | |
| 42 | W | B | 0.0000 | |
| 43 | L | B | 0.0000 | |
| 44 | L | B | 0.0000 | |
| 45 | I | B | 0.0000 | |
| 46 | D | B | 0.0000 | |
| 47 | G | B | 0.0000 | |
| 48 | E | B | 0.0000 | |
| 49 | H | B | 0.0000 | |
| 50 | A | B | 0.0000 | |
| 51 | P | B | -0.1113 | |
| 52 | N | B | 0.0000 | |
| 53 | T | B | -0.1536 | |
| 54 | I | B | 0.0177 | |
| 55 | Q | B | -0.4541 | |
| 56 | D | B | -0.7552 | |
| 57 | L | B | 0.0000 | |
| 58 | Y | B | -0.7116 | |
| 59 | H | B | -1.3734 | |
| 60 | Q | B | 0.0000 | |
| 61 | L | B | 0.0000 | |
| 62 | Q | B | -1.6876 | |
| 63 | A | B | -0.7394 | |
| 64 | V | B | 0.0000 | |
| 65 | A | B | -0.5978 | |
| 66 | P | B | -0.3338 | |
| 67 | Y | B | 0.0682 | |
| 68 | A | B | -0.0410 | |
| 69 | S | B | 0.0000 | |
| 70 | Q | B | -0.2850 | |
| 71 | P | B | -0.1490 | |
| 72 | V | B | 0.0000 | |
| 73 | I | B | 0.0000 | |
| 74 | R | B | 0.0000 | |
| 75 | P | B | 0.0000 | |
| 76 | V | B | 0.0682 | |
| 77 | E | B | -0.3993 | |
| 78 | G | B | -0.4886 | |
| 79 | S | B | -0.5773 | |
| 80 | K | B | -1.0867 | |
| 81 | P | B | -0.2767 | |
| 82 | L | B | 0.1566 | |
| 83 | I | B | 0.0000 | |
| 84 | K | B | 0.0000 | |
| 85 | Q | B | 0.0000 | |
| 86 | V | B | 0.0000 | |
| 87 | L | B | 0.0000 | |
| 88 | D | B | 0.0000 | |
| 89 | I | B | 0.0000 | |
| 90 | G | B | -0.1639 | |
| 91 | A | B | 0.0000 | |
| 92 | Q | B | -0.3347 | |
| 93 | T | B | 0.0000 | |
| 94 | L | B | 0.0000 | |
| 95 | L | B | 0.0000 | |
| 96 | I | B | 0.0000 | |
| 97 | P | B | 0.0000 | |
| 98 | M | B | -0.1552 | |
| 99 | V | B | 0.0000 | |
| 100 | D | B | -1.2249 | |
| 101 | T | B | -2.1145 | |
| 102 | A | B | 0.0000 | |
| 103 | E | B | -3.2433 | |
| 104 | Q | B | -2.4273 | |
| 105 | A | B | 0.0000 | |
| 106 | R | B | -3.5774 | |
| 107 | Q | B | -2.6345 | |
| 108 | V | B | 0.0000 | |
| 109 | V | B | 0.0000 | |
| 110 | S | B | -1.3916 | |
| 111 | A | B | 0.0000 | |
| 112 | T | B | 0.0000 | |
| 113 | R | B | -0.8227 | |
| 114 | Y | B | 0.0000 | |
| 115 | P | B | -0.3575 | |
| 116 | P | B | -0.0847 | |
| 117 | Y | B | 0.5342 | |
| 118 | G | B | -0.8870 | |
| 119 | E | B | -1.9438 | |
| 120 | R | B | 0.0000 | |
| 121 | G | B | -0.5209 | |
| 122 | V | B | -0.0389 | |
| 123 | G | B | 0.0286 | |
| 124 | A | B | 0.0000 | |
| 125 | S | B | -0.7213 | |
| 126 | V | B | 0.0000 | |
| 127 | A | B | 0.0000 | |
| 128 | R | B | 0.0000 | |
| 129 | A | B | 0.0000 | |
| 130 | A | B | 0.0000 | |
| 131 | R | B | -1.0694 | |
| 132 | W | B | -0.7849 | |
| 133 | G | B | -1.7462 | |
| 134 | R | B | -1.6795 | |
| 135 | I | B | 0.0000 | |
| 136 | E | B | -2.6441 | |
| 137 | N | B | -2.2923 | |
| 138 | Y | B | 0.0000 | |
| 139 | M | B | -1.0219 | |
| 140 | A | B | -1.4342 | |
| 141 | Q | B | -1.1791 | |
| 142 | V | B | 0.0000 | |
| 143 | N | B | -2.0959 | |
| 144 | D | B | -2.5517 | |
| 145 | S | B | 0.0000 | |
| 146 | L | B | -1.0075 | |
| 147 | C | B | 0.0000 | |
| 148 | L | B | 0.0000 | |
| 149 | L | B | 0.0000 | |
| 150 | V | B | 0.0000 | |
| 151 | Q | B | 0.0000 | |
| 152 | V | B | 0.0000 | |
| 153 | E | B | -0.4984 | |
| 154 | S | B | -1.0933 | |
| 155 | K | B | -1.8386 | |
| 156 | T | B | -1.4674 | |
| 157 | A | B | 0.0000 | |
| 158 | L | B | -1.6862 | |
| 159 | D | B | -2.7728 | |
| 160 | N | B | -2.4799 | |
| 161 | L | B | 0.0000 | |
| 162 | D | B | -3.7921 | |
| 163 | E | B | -3.8526 | |
| 164 | I | B | 0.0000 | |
| 165 | L | B | 0.0000 | |
| 166 | D | B | -3.6452 | |
| 167 | V | B | 0.0000 | |
| 168 | E | B | -2.7817 | |
| 169 | G | B | -2.1358 | |
| 170 | I | B | 0.0000 | |
| 171 | D | B | -1.0958 | |
| 172 | G | B | 0.0000 | |
| 173 | V | B | 0.0000 | |
| 174 | F | B | 0.0000 | |
| 175 | I | B | 0.0000 | |
| 176 | G | B | 0.0000 | |
| 177 | P | B | -0.3933 | |
| 178 | A | B | -0.8482 | |
| 179 | D | B | -0.5229 | |
| 180 | L | B | 0.0000 | |
| 181 | S | B | 0.0000 | |
| 182 | A | B | 0.0000 | |
| 183 | S | B | 0.0000 | |
| 184 | L | B | -0.4171 | |
| 185 | G | B | -0.4665 | |
| 186 | Y | B | -1.1212 | |
| 187 | P | B | -1.3410 | |
| 188 | D | B | -2.6780 | |
| 189 | N | B | -2.4030 | |
| 190 | A | B | -1.7059 | |
| 191 | G | B | -1.7794 | |
| 192 | H | B | -1.9951 | |
| 193 | P | B | -1.8472 | |
| 194 | E | B | -2.1977 | |
| 195 | V | B | 0.0000 | |
| 196 | Q | B | -1.9145 | |
| 197 | R | B | -2.5832 | |
| 198 | I | B | -1.0223 | |
| 199 | I | B | 0.0000 | |
| 200 | E | B | -1.9537 | |
| 201 | T | B | -1.7231 | |
| 202 | S | B | 0.0000 | |
| 203 | I | B | 0.0000 | |
| 204 | R | B | -2.8567 | |
| 205 | R | B | -3.3342 | |
| 206 | I | B | 0.0000 | |
| 207 | R | B | -2.1013 | |
| 208 | A | B | -1.7486 | |
| 209 | A | B | -1.7483 | |
| 210 | G | B | -1.5560 | |
| 211 | K | B | -1.5945 | |
| 212 | A | B | 0.0000 | |
| 213 | A | B | 0.0000 | |
| 214 | G | B | 0.0000 | |
| 215 | F | B | 0.0000 | |
| 216 | L | B | 0.7818 | |
| 217 | A | B | 0.0000 | |
| 218 | V | B | 1.4325 | |
| 219 | A | B | 0.0222 | |
| 220 | P | B | -0.9873 | |
| 221 | D | B | -2.1305 | |
| 222 | M | B | -1.0522 | |
| 223 | A | B | 0.0000 | |
| 224 | Q | B | -1.8087 | |
| 225 | Q | B | -1.4636 | |
| 226 | C | B | 0.0000 | |
| 227 | L | B | 0.2305 | |
| 228 | A | B | -0.2627 | |
| 229 | W | B | -0.6574 | |
| 230 | G | B | -0.5499 | |
| 231 | A | B | 0.0000 | |
| 232 | N | B | 0.0000 | |
| 233 | F | B | 0.0000 | |
| 234 | V | B | 0.0000 | |
| 235 | A | B | 0.0000 | |
| 236 | V | B | 0.8661 | |
| 237 | G | B | 0.0000 | |
| 238 | V | B | 0.0000 | |
| 239 | D | B | 0.0000 | |
| 240 | T | B | 0.3267 | |
| 241 | M | B | 0.6176 | |
| 242 | L | B | 0.7988 | |
| 243 | Y | B | 0.4878 | |
| 244 | S | B | -0.2809 | |
| 245 | D | B | -1.5178 | |
| 246 | A | B | -0.6165 | |
| 247 | L | B | 0.3214 | |
| 248 | D | B | -0.9070 | |
| 249 | Q | B | -1.4514 | |
| 250 | R | B | -1.1427 | |
| 251 | L | B | 0.7814 | |
| 252 | A | B | 0.3034 | |
| 253 | M | B | 1.0360 | |
| 254 | F | B | 1.5635 | |
| 255 | K | B | -0.3840 | |
| 256 | S | B | 0.1557 | |
| 1 | M | C | 0.4074 | |
| 2 | N | C | -0.6894 | |
| 3 | A | C | -0.6713 | |
| 4 | L | C | 0.6197 | |
| 5 | L | C | -0.0881 | |
| 6 | S | C | -0.3824 | |
| 7 | N | C | 0.0000 | |
| 8 | P | C | -1.0909 | |
| 9 | F | C | 0.0000 | |
| 10 | K | C | 0.0000 | |
| 11 | E | C | -3.0883 | |
| 12 | R | C | -2.5507 | |
| 13 | L | C | 0.0000 | |
| 14 | R | C | -3.6103 | |
| 15 | K | C | -3.2750 | |
| 16 | G | C | -2.1342 | |
| 17 | E | C | -1.3076 | |
| 18 | V | C | 0.6687 | |
| 19 | Q | C | 0.0000 | |
| 20 | I | C | 0.7656 | |
| 21 | G | C | 0.0000 | |
| 22 | L | C | 0.0000 | |
| 23 | W | C | 0.0000 | |
| 24 | L | C | 0.0000 | |
| 25 | S | C | 0.0000 | |
| 26 | S | C | 0.1305 | |
| 27 | T | C | -0.0961 | |
| 28 | T | C | 0.1114 | |
| 29 | A | C | 0.0727 | |
| 30 | Y | C | 1.2704 | |
| 31 | M | C | 0.9775 | |
| 32 | A | C | 0.0000 | |
| 33 | E | C | -0.2041 | |
| 34 | I | C | 0.9147 | |
| 35 | A | C | 0.0000 | |
| 36 | A | C | 0.0000 | |
| 37 | T | C | -0.1002 | |
| 38 | S | C | -0.3085 | |
| 39 | G | C | -0.4612 | |
| 40 | Y | C | -0.0735 | |
| 41 | D | C | -0.2130 | |
| 42 | W | C | 0.0000 | |
| 43 | L | C | 0.0000 | |
| 44 | L | C | 0.0000 | |
| 45 | I | C | 0.0000 | |
| 46 | D | C | 0.0000 | |
| 47 | G | C | 0.0000 | |
| 48 | E | C | 0.0000 | |
| 49 | H | C | 0.0000 | |
| 50 | A | C | 0.0000 | |
| 51 | P | C | -0.0427 | |
| 52 | N | C | 0.0000 | |
| 53 | T | C | -0.2155 | |
| 54 | I | C | 0.0000 | |
| 55 | Q | C | -0.5454 | |
| 56 | D | C | -0.8103 | |
| 57 | L | C | 0.0000 | |
| 58 | Y | C | -0.7520 | |
| 59 | H | C | -1.3912 | |
| 60 | Q | C | 0.0000 | |
| 61 | L | C | 0.0000 | |
| 62 | Q | C | -1.6773 | |
| 63 | A | C | -0.6946 | |
| 64 | V | C | 0.0000 | |
| 65 | A | C | -0.6268 | |
| 66 | P | C | -0.3605 | |
| 67 | Y | C | 0.0090 | |
| 68 | A | C | -0.0605 | |
| 69 | S | C | 0.0000 | |
| 70 | Q | C | -0.3825 | |
| 71 | P | C | -0.2165 | |
| 72 | V | C | 0.0000 | |
| 73 | I | C | 0.0000 | |
| 74 | R | C | 0.0000 | |
| 75 | P | C | 0.0000 | |
| 76 | V | C | 0.0765 | |
| 77 | E | C | -0.3709 | |
| 78 | G | C | -0.4033 | |
| 79 | S | C | -0.4365 | |
| 80 | K | C | -0.7816 | |
| 81 | P | C | -0.3526 | |
| 82 | L | C | 0.0059 | |
| 83 | I | C | 0.0000 | |
| 84 | K | C | 0.0000 | |
| 85 | Q | C | -0.1154 | |
| 86 | V | C | 0.0000 | |
| 87 | L | C | 0.0000 | |
| 88 | D | C | 0.0000 | |
| 89 | I | C | 0.0000 | |
| 90 | G | C | -0.1810 | |
| 91 | A | C | 0.0000 | |
| 92 | Q | C | -0.3730 | |
| 93 | T | C | 0.0000 | |
| 94 | L | C | 0.0000 | |
| 95 | L | C | 0.0000 | |
| 96 | I | C | 0.0000 | |
| 97 | P | C | 0.0000 | |
| 98 | M | C | -0.2266 | |
| 99 | V | C | 0.0000 | |
| 100 | D | C | -1.2908 | |
| 101 | T | C | -2.0633 | |
| 102 | A | C | -2.7899 | |
| 103 | E | C | -3.1541 | |
| 104 | Q | C | -2.2695 | |
| 105 | A | C | 0.0000 | |
| 106 | R | C | -3.4698 | |
| 107 | Q | C | -2.3627 | |
| 108 | V | C | 0.0000 | |
| 109 | V | C | 0.0000 | |
| 110 | S | C | -1.0654 | |
| 111 | A | C | 0.0000 | |
| 112 | T | C | 0.0000 | |
| 113 | R | C | -0.6716 | |
| 114 | Y | C | 0.0000 | |
| 115 | P | C | -0.0966 | |
| 116 | P | C | 0.1469 | |
| 117 | Y | C | 0.8435 | |
| 118 | G | C | -0.3970 | |
| 119 | E | C | -0.9387 | |
| 120 | R | C | 0.0000 | |
| 121 | G | C | -0.4056 | |
| 122 | V | C | -0.3368 | |
| 123 | G | C | 0.0090 | |
| 124 | A | C | 0.0000 | |
| 125 | S | C | -0.6098 | |
| 126 | V | C | 0.1062 | |
| 127 | A | C | 0.0000 | |
| 128 | R | C | 0.0000 | |
| 129 | A | C | 0.0000 | |
| 130 | A | C | 0.0000 | |
| 131 | R | C | -0.9534 | |
| 132 | W | C | -0.4802 | |
| 133 | G | C | -1.4040 | |
| 134 | R | C | -1.6374 | |
| 135 | I | C | 0.0000 | |
| 136 | E | C | -2.6157 | |
| 137 | N | C | -2.3406 | |
| 138 | Y | C | 0.0000 | |
| 139 | M | C | -1.1168 | |
| 140 | A | C | -1.2972 | |
| 141 | Q | C | -1.1950 | |
| 142 | V | C | 0.0000 | |
| 143 | N | C | -2.2444 | |
| 144 | D | C | -2.5539 | |
| 145 | S | C | 0.0000 | |
| 146 | L | C | -0.9723 | |
| 147 | C | C | 0.0000 | |
| 148 | L | C | 0.0000 | |
| 149 | L | C | 0.0000 | |
| 150 | V | C | 0.0000 | |
| 151 | Q | C | 0.0000 | |
| 152 | V | C | 0.0000 | |
| 153 | E | C | -0.4879 | |
| 154 | S | C | -1.1664 | |
| 155 | K | C | -1.5684 | |
| 156 | T | C | -1.3666 | |
| 157 | A | C | 0.0000 | |
| 158 | L | C | -1.4829 | |
| 159 | D | C | -2.6149 | |
| 160 | N | C | -2.2676 | |
| 161 | L | C | 0.0000 | |
| 162 | D | C | -3.0771 | |
| 163 | E | C | -3.5198 | |
| 164 | I | C | 0.0000 | |
| 165 | L | C | 0.0000 | |
| 166 | D | C | -3.4416 | |
| 167 | V | C | 0.0000 | |
| 168 | E | C | -2.6952 | |
| 169 | G | C | -1.7838 | |
| 170 | I | C | 0.0000 | |
| 171 | D | C | 0.0000 | |
| 172 | G | C | 0.0000 | |
| 173 | V | C | 0.0000 | |
| 174 | F | C | 0.0000 | |
| 175 | I | C | 0.0000 | |
| 176 | G | C | 0.0000 | |
| 177 | P | C | -0.4219 | |
| 178 | A | C | -0.5700 | |
| 179 | D | C | -0.4447 | |
| 180 | L | C | 0.0000 | |
| 181 | S | C | 0.0000 | |
| 182 | A | C | 0.0000 | |
| 183 | S | C | 0.0000 | |
| 184 | L | C | -0.2423 | |
| 185 | G | C | 0.0643 | |
| 186 | Y | C | -0.5195 | |
| 187 | P | C | -1.1122 | |
| 188 | D | C | -1.8740 | |
| 189 | N | C | -2.4331 | |
| 190 | A | C | -1.0792 | |
| 191 | G | C | -1.4203 | |
| 192 | H | C | -1.5309 | |
| 193 | P | C | -1.9115 | |
| 194 | E | C | -2.4474 | |
| 195 | V | C | 0.0000 | |
| 196 | Q | C | -2.2456 | |
| 197 | R | C | -2.2524 | |
| 198 | I | C | -0.5339 | |
| 199 | I | C | 0.0000 | |
| 200 | E | C | 0.0000 | |
| 201 | T | C | -1.4206 | |
| 202 | S | C | 0.0000 | |
| 203 | I | C | 0.0000 | |
| 204 | R | C | -2.7643 | |
| 205 | R | C | -2.8507 | |
| 206 | I | C | 0.0000 | |
| 207 | R | C | -2.0432 | |
| 208 | A | C | -1.5301 | |
| 209 | A | C | -1.6073 | |
| 210 | G | C | -1.4322 | |
| 211 | K | C | -1.3853 | |
| 212 | A | C | 0.0000 | |
| 213 | A | C | 0.0000 | |
| 214 | G | C | 0.0000 | |
| 215 | F | C | 0.0000 | |
| 216 | L | C | 0.8952 | |
| 217 | A | C | 0.0000 | |
| 218 | V | C | 1.8728 | |
| 219 | A | C | 0.1724 | |
| 220 | P | C | -0.8887 | |
| 221 | D | C | -2.0927 | |
| 222 | M | C | -0.8867 | |
| 223 | A | C | 0.0000 | |
| 224 | Q | C | -1.8343 | |
| 225 | Q | C | -1.3891 | |
| 226 | C | C | 0.0000 | |
| 227 | L | C | 0.1086 | |
| 228 | A | C | -0.1833 | |
| 229 | W | C | -0.5685 | |
| 230 | G | C | -0.5717 | |
| 231 | A | C | 0.0000 | |
| 232 | N | C | 0.0000 | |
| 233 | F | C | 0.0000 | |
| 234 | V | C | 0.0000 | |
| 235 | A | C | 0.0000 | |
| 236 | V | C | 1.0594 | |
| 237 | G | C | 0.0000 | |
| 238 | V | C | 0.0000 | |
| 239 | D | C | 0.0000 | |
| 240 | T | C | 0.7459 | |
| 241 | M | C | 1.0201 | |
| 242 | L | C | 1.4029 | |
| 243 | Y | C | 1.3597 | |
| 244 | S | C | 0.0558 | |
| 245 | D | C | -1.3544 | |
| 246 | A | C | -0.4680 | |
| 247 | L | C | 0.1599 | |
| 248 | D | C | -0.9534 | |
| 249 | Q | C | -1.4750 | |
| 250 | R | C | -1.2658 | |
| 251 | L | C | 0.6873 | |
| 252 | A | C | 0.3097 | |
| 253 | M | C | 1.1045 | |
| 254 | F | C | 1.6023 | |
| 255 | K | C | -0.3670 | |
| 256 | S | C | -0.2739 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine