Project name: AFV157851Leucoagaricus_gongylophorus

Chain sequence(s)	A: IGPVTDLHIANTVVSPDGFPREAITTEGQLPGPLITGYKASRMLGDNFQINVINNLTDETLNTSTSIHWHGFFQHGTNWADGAAYVTQCPIVTGNSFLYNFTVPDQAGTFWYHSHLALQYCDGLRGPLVVYDPHDPYADMYDVDNASTVITLADWYHQPADTIKPPHLASATLINGLGRYVGGPASPLTVITVEQGKRYRFRLVSMACDPSYDFSIDGHDMTIIEVDGVNSKPLTVDEIQIFAAQRYSFILNATRPVGNYWIRAQPNAQQLLVGYIGGINSAILRYIGAPDIDPITVKTPSIKPLQEVNLHPLIDPAAPGKPTPDGANVVIPLNLSIANGQFLINGTTFAPPTTPVLLQIPSGAKPAQKLLPPGSVYTLPKNSTIEIIIPPGTAPGGPHPFHLHGHTFSVVRSAGSSVYNYANPVRRDTVSIGTGKNDAVTIRFTTDNPGPWFIHCHIDFHLNAGLAVVMAEDIPDVASANPVPTAWDQLCPIYDQ
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.0188
• Maximal score value: 2.01
• Average score: -0.1357
• Total score value: -67.3064

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
25	I	A	1.0604
26	G	A	0.1783
27	P	A	0.1627
28	V	A	1.2591
29	T	A	-0.1187
30	D	A	-1.8219
31	L	A	0.0000
32	H	A	-0.5811
33	I	A	0.0000
34	A	A	-0.0464
35	N	A	-0.3394
36	T	A	0.2322
37	V	A	1.5871
38	V	A	0.5537
39	S	A	-0.1433
40	P	A	0.0000
41	D	A	0.0000
42	G	A	-0.2254
43	F	A	0.6832
44	P	A	-0.1378
45	R	A	0.0000
46	E	A	-1.3336
47	A	A	0.0000
48	I	A	0.0000
49	T	A	0.0000
50	T	A	0.0000
51	E	A	-0.8962
52	G	A	-0.7546
53	Q	A	-0.8243
54	L	A	0.0560
55	P	A	0.0316
56	G	A	0.0000
57	P	A	0.0061
58	L	A	0.1887
59	I	A	0.0000
60	T	A	-0.0232
61	G	A	0.0737
62	Y	A	0.6471
63	K	A	-0.2386
64	A	A	0.0000
65	S	A	-0.5489
66	R	A	-1.8112
67	M	A	0.3282
68	L	A	1.6082
69	G	A	0.3415
70	D	A	0.0000
71	N	A	-0.5231
72	F	A	0.0000
73	Q	A	-0.2294
74	I	A	0.0000
75	N	A	-0.3685
76	V	A	0.0000
77	I	A	0.1321
78	N	A	0.0000
79	N	A	-0.7328
80	L	A	0.0000
81	T	A	-0.1611
82	D	A	-0.8338
83	E	A	-1.9910
84	T	A	-0.3986
85	L	A	0.0000
86	N	A	-0.8047
87	T	A	-0.1165
88	S	A	0.0000
89	T	A	0.0000
90	S	A	0.0000
91	I	A	0.0000
92	H	A	0.0000
93	W	A	0.0000
94	H	A	0.0000
95	G	A	0.0000
96	F	A	0.0000
97	F	A	0.4983
98	Q	A	0.0000
99	H	A	-0.8663
100	G	A	-0.2631
101	T	A	-0.0286
102	N	A	0.0000
103	W	A	0.0000
104	A	A	0.0000
105	D	A	0.0000
106	G	A	0.0000
107	A	A	0.0000
108	A	A	0.0000
109	Y	A	0.1697
110	V	A	0.0000
111	T	A	0.0000
112	Q	A	0.0000
113	C	A	0.0000
114	P	A	0.0000
115	I	A	0.0000
116	V	A	0.3556
117	T	A	-0.0638
118	G	A	-0.6155
119	N	A	-0.8856
120	S	A	-0.2825
121	F	A	0.0000
122	L	A	0.6197
123	Y	A	0.0000
124	N	A	-0.5667
125	F	A	0.0000
126	T	A	-0.0925
127	V	A	0.0000
128	P	A	-0.4359
129	D	A	-1.8094
130	Q	A	0.0000
131	A	A	0.0097
132	G	A	0.0000
133	T	A	0.0000
134	F	A	0.0000
135	W	A	0.0000
136	Y	A	0.0000
137	H	A	0.0000
138	S	A	0.0000
139	H	A	0.0000
140	L	A	0.0000
141	A	A	0.0903
142	L	A	0.1877
143	Q	A	0.0000
144	Y	A	0.0000
145	C	A	0.0000
146	D	A	0.0000
147	G	A	0.0000
148	L	A	0.0000
149	R	A	0.0000
150	G	A	0.0000
151	P	A	0.0000
152	L	A	0.0000
153	V	A	0.0000
154	V	A	0.0000
155	Y	A	0.2263
156	D	A	-0.3495
157	P	A	-0.3562
158	H	A	-1.0443
159	D	A	-0.4475
160	P	A	-0.2880
161	Y	A	0.0000
162	A	A	-0.2733
163	D	A	-1.7115
164	M	A	0.0815
165	Y	A	-0.1001
166	D	A	-1.0366
167	V	A	-0.0207
168	D	A	-0.5232
169	N	A	-0.9648
170	A	A	-0.1419
171	S	A	-0.2024
172	T	A	0.0000
173	V	A	0.0000
174	I	A	0.0000
175	T	A	0.0000
176	L	A	0.0000
177	A	A	0.0000
178	D	A	0.0000
179	W	A	0.0000
180	Y	A	0.0000
181	H	A	-0.4034
182	Q	A	-1.2615
183	P	A	-0.3683
184	A	A	-0.3035
185	D	A	-1.7875
186	T	A	-0.0219
187	I	A	1.7580
188	K	A	-1.0286
189	P	A	-0.3227
190	P	A	-0.2617
191	H	A	0.0000
192	L	A	1.5489
193	A	A	0.2864
194	S	A	-0.0465
195	A	A	0.0000
196	T	A	0.0000
197	L	A	0.0000
198	I	A	0.0000
199	N	A	-0.3943
200	G	A	-0.0484
201	L	A	0.3572
202	G	A	0.0000
203	R	A	-0.1680
204	Y	A	0.3917
205	V	A	0.9228
206	G	A	-0.3111
207	G	A	-0.1835
208	P	A	-0.1742
209	A	A	0.0243
210	S	A	-0.0548
211	P	A	-0.2296
212	L	A	0.1100
213	T	A	0.1667
214	V	A	0.7851
215	I	A	0.0000
216	T	A	-0.0895
217	V	A	0.0000
218	E	A	-1.6415
219	Q	A	-1.5403
220	G	A	-0.8164
221	K	A	-0.9929
222	R	A	-1.1509
223	Y	A	0.0000
224	R	A	0.0000
225	F	A	0.0000
226	R	A	0.0000
227	L	A	0.0000
228	V	A	0.0000
229	S	A	0.0000
230	M	A	0.0000
231	A	A	0.0000
232	C	A	0.0000
233	D	A	-0.2904
234	P	A	0.0000
235	S	A	0.0102
236	Y	A	0.0000
237	D	A	-0.7985
238	F	A	0.0000
239	S	A	-0.0855
240	I	A	0.0000
241	D	A	0.0000
242	G	A	-0.4663
243	H	A	0.0000
244	D	A	-1.8298
245	M	A	0.0000
246	T	A	-0.0196
247	I	A	0.0000
248	I	A	0.0000
249	E	A	0.0000
250	V	A	0.0000
251	D	A	0.0000
252	G	A	-0.0853
253	V	A	0.0000
254	N	A	-0.2403
255	S	A	0.0000
256	K	A	-0.9810
257	P	A	-0.3684
258	L	A	0.1540
259	T	A	-0.0340
260	V	A	0.0000
261	D	A	-0.6271
262	E	A	-0.5037
263	I	A	0.0000
264	Q	A	-0.7583
265	I	A	0.0000
266	F	A	0.2266
267	A	A	0.0000
268	A	A	0.0000
269	Q	A	0.0000
270	R	A	0.0000
271	Y	A	0.0000
272	S	A	0.0000
273	F	A	0.0000
274	I	A	0.0000
275	L	A	0.0000
276	N	A	-0.8352
277	A	A	0.0000
278	T	A	-0.2998
279	R	A	-1.2996
280	P	A	-0.3108
281	V	A	0.8622
282	G	A	0.0834
283	N	A	-0.1602
284	Y	A	0.0000
285	W	A	0.1524
286	I	A	0.0000
287	R	A	0.0000
288	A	A	0.0000
289	Q	A	-0.4232
290	P	A	0.0000
291	N	A	-1.2704
292	A	A	-0.2364
293	Q	A	-0.1606
294	Q	A	0.1012
295	L	A	1.9168
296	L	A	1.9448
297	V	A	0.0000
298	G	A	-0.0675
299	Y	A	0.4656
300	I	A	1.6343
301	G	A	-0.1705
302	G	A	-0.1345
303	I	A	0.0000
304	N	A	0.0000
305	S	A	0.0000
306	A	A	0.0000
307	I	A	0.0000
308	L	A	0.0000
309	R	A	-0.2096
310	Y	A	0.0000
311	I	A	1.8559
312	G	A	-0.1132
313	A	A	-0.1307
314	P	A	-0.5779
315	D	A	-1.4668
316	I	A	1.3597
317	D	A	-1.4239
318	P	A	0.0000
319	I	A	2.0100
320	T	A	0.6715
321	V	A	1.4622
322	K	A	-1.3917
323	T	A	-0.4251
324	P	A	-0.3051
325	S	A	0.1055
326	I	A	1.6662
327	K	A	-1.3501
328	P	A	-0.4409
329	L	A	0.0000
330	Q	A	-1.1841
331	E	A	-0.2620
332	V	A	1.0682
333	N	A	-0.7533
334	L	A	0.0000
335	H	A	-0.3385
336	P	A	0.0000
337	L	A	0.5039
338	I	A	1.0716
339	D	A	-1.5545
340	P	A	-0.3770
341	A	A	0.0217
342	A	A	0.0042
343	P	A	-0.0938
344	G	A	-0.5366
345	K	A	-1.7857
346	P	A	-0.5747
347	T	A	-0.1456
348	P	A	-0.5471
349	D	A	-1.8274
350	G	A	0.0000
351	A	A	-0.2410
352	N	A	-1.2338
353	V	A	0.0460
354	V	A	0.5938
355	I	A	0.6991
356	P	A	-0.1369
357	L	A	0.0000
358	N	A	-1.4136
359	L	A	0.0000
360	S	A	-0.0001
361	I	A	0.3598
362	A	A	-0.1074
363	N	A	-1.2771
364	G	A	-0.6486
365	Q	A	-0.9286
366	F	A	0.0000
367	L	A	0.2603
368	I	A	0.0000
369	N	A	-1.4985
370	G	A	-0.7008
371	T	A	-0.0755
372	T	A	0.0205
373	F	A	0.0000
374	A	A	0.0136
375	P	A	-0.2446
376	P	A	0.0000
377	T	A	-0.0771
378	T	A	-0.0473
379	P	A	0.0000
380	V	A	0.0000
381	L	A	0.0000
382	L	A	0.3030
383	Q	A	0.0000
384	I	A	0.0000
385	P	A	-0.1629
386	S	A	-0.3206
387	G	A	-0.5037
388	A	A	-0.2213
389	K	A	-0.8179
390	P	A	-0.2597
391	A	A	-0.2289
392	Q	A	-1.5057
393	K	A	-1.9177
394	L	A	0.0000
395	L	A	1.2344
396	P	A	0.2810
397	P	A	-0.2025
398	G	A	-0.5122
399	S	A	0.0000
400	V	A	0.0000
401	Y	A	0.3832
402	T	A	0.0510
403	L	A	0.0000
404	P	A	-0.4200
405	K	A	-1.8198
406	N	A	-1.5572
407	S	A	0.0000
408	T	A	-0.0165
409	I	A	0.0000
410	E	A	0.0000
411	I	A	0.0000
412	I	A	0.0000
413	I	A	0.0000
414	P	A	0.0000
415	P	A	-0.1373
416	G	A	0.0000
417	T	A	-0.3282
418	A	A	0.0000
419	P	A	-0.3392
420	G	A	-0.5479
421	G	A	-0.2887
422	P	A	-0.0978
423	H	A	0.0000
424	P	A	0.0000
425	F	A	0.0000
426	H	A	0.0000
427	L	A	0.0000
428	H	A	0.0000
429	G	A	0.0000
430	H	A	0.0000
431	T	A	-0.0097
432	F	A	0.0000
433	S	A	0.0000
434	V	A	0.0000
435	V	A	0.0000
436	R	A	-0.1487
437	S	A	0.0000
438	A	A	-0.0582
439	G	A	-0.4770
440	S	A	-0.2075
441	S	A	0.1004
442	V	A	1.7870
443	Y	A	0.5350
444	N	A	-0.2424
445	Y	A	0.1612
446	A	A	-0.0511
447	N	A	-0.8026
448	P	A	0.0000
449	V	A	0.0000
450	R	A	-0.6817
451	R	A	0.0000
452	D	A	0.0000
453	T	A	0.0000
454	V	A	0.0000
455	S	A	0.0000
456	I	A	0.0000
457	G	A	0.0000
458	T	A	-0.1609
459	G	A	-0.7928
460	K	A	-2.0188
461	N	A	-1.6126
462	D	A	-0.4449
463	A	A	-0.0501
464	V	A	0.0000
465	T	A	0.0000
466	I	A	0.0000
467	R	A	0.0000
468	F	A	0.0000
469	T	A	-0.0547
470	T	A	0.0000
471	D	A	-1.7894
472	N	A	0.0000
473	P	A	-0.0300
474	G	A	0.0000
475	P	A	0.0000
476	W	A	0.0000
477	F	A	0.0000
478	I	A	0.0000
479	H	A	0.0000
480	C	A	0.0000
481	H	A	0.0000
482	I	A	0.0000
483	D	A	0.0000
484	F	A	0.0000
485	H	A	0.0000
486	L	A	0.0703
487	N	A	-0.5627
488	A	A	0.0000
489	G	A	0.0000
490	L	A	0.0000
491	A	A	0.0000
492	V	A	0.0000
493	V	A	0.0000
494	M	A	0.0000
495	A	A	0.0000
496	E	A	0.0000
497	D	A	0.0000
498	I	A	0.0000
499	P	A	-0.3933
500	D	A	-0.8115
501	V	A	0.0000
502	A	A	-0.0071
503	S	A	-0.2042
504	A	A	-0.0223
505	N	A	0.0000
506	P	A	-0.1370
507	V	A	0.5811
508	P	A	0.0063
509	T	A	-0.0815
510	A	A	0.0245
511	W	A	0.0000
512	D	A	-1.9674
513	Q	A	-1.3071
514	L	A	0.0000
515	C	A	0.0000
516	P	A	-0.0869
517	I	A	0.6416
518	Y	A	0.2095
519	D	A	-1.9261
520	Q	A	-1.5169