Project name: 3eob:L
Status: done
submitted: 2019-03-20 20:08:43, status changed: 2019-03-20 20:17:46
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRASKTISKYLAWYQQKPGKAPKLLIYSGSTLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQHNEYPLTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8705
-
Maximal score value
-
1.7527
-
Average score
-
-0.8698
-
Total score value
-
-186.1288
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.1022 |
|
| 2 |
I |
L |
-1.3963 |
|
| 3 |
Q |
L |
-1.9143 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.2027 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.6898 |
|
| 8 |
P |
L |
-0.5530 |
|
| 9 |
S |
L |
-0.7416 |
|
| 10 |
S |
L |
-0.5665 |
|
| 11 |
L |
L |
-0.3754 |
|
| 12 |
S |
L |
-0.7589 |
|
| 13 |
A |
L |
-1.0635 |
|
| 14 |
S |
L |
-1.1092 |
|
| 15 |
V |
L |
-0.5411 |
|
| 16 |
G |
L |
-0.9982 |
|
| 17 |
D |
L |
-1.9281 |
|
| 18 |
R |
L |
-2.4273 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6691 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.9647 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.8699 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-2.1120 |
|
| 27 |
K |
L |
-2.5457 |
|
| 28 |
T |
L |
-1.7259 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
S |
L |
-1.4303 |
|
| 31 |
K |
L |
-1.8233 |
|
| 32 |
Y |
L |
-0.8675 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.0620 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.3461 |
|
| 39 |
K |
L |
-1.9297 |
|
| 40 |
P |
L |
-1.4999 |
|
| 41 |
G |
L |
-1.6828 |
|
| 42 |
K |
L |
-2.3335 |
|
| 43 |
A |
L |
-1.3845 |
|
| 44 |
P |
L |
-1.2492 |
|
| 45 |
K |
L |
-1.4339 |
|
| 46 |
L |
L |
-0.1319 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.3468 |
|
| 50 |
S |
L |
-0.3093 |
|
| 51 |
G |
L |
0.0000 |
|
| 52 |
S |
L |
-0.4118 |
|
| 53 |
T |
L |
0.0831 |
|
| 54 |
L |
L |
0.2713 |
|
| 55 |
Q |
L |
-0.2916 |
|
| 56 |
S |
L |
-0.4199 |
|
| 57 |
G |
L |
-0.5030 |
|
| 58 |
V |
L |
-0.3435 |
|
| 59 |
P |
L |
-0.3937 |
|
| 60 |
S |
L |
-0.4630 |
|
| 61 |
R |
L |
-0.7864 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.2778 |
|
| 64 |
G |
L |
-0.2291 |
|
| 65 |
S |
L |
-0.9896 |
|
| 66 |
G |
L |
-1.5086 |
|
| 67 |
S |
L |
-1.6446 |
|
| 68 |
G |
L |
-1.6282 |
|
| 69 |
T |
L |
-2.2537 |
|
| 70 |
D |
L |
-3.0126 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.9144 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6224 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.4670 |
|
| 77 |
S |
L |
-1.2963 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.2113 |
|
| 80 |
P |
L |
-2.0248 |
|
| 81 |
E |
L |
-2.6063 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-0.7230 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0536 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
H |
L |
-0.6073 |
|
| 92 |
N |
L |
-1.5858 |
|
| 93 |
E |
L |
-1.6293 |
|
| 94 |
Y |
L |
0.1579 |
|
| 95 |
P |
L |
0.2909 |
|
| 96 |
L |
L |
0.8662 |
|
| 97 |
T |
L |
0.4109 |
|
| 98 |
F |
L |
1.2502 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-1.0967 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.1270 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-0.9651 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.4644 |
|
| 108 |
R |
L |
-1.0784 |
|
| 109 |
T |
L |
0.0060 |
|
| 110 |
V |
L |
0.9576 |
|
| 111 |
A |
L |
0.0152 |
|
| 112 |
A |
L |
-0.1874 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1811 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.2672 |
|
| 117 |
I |
L |
1.3649 |
|
| 118 |
F |
L |
1.7527 |
|
| 119 |
P |
L |
0.1668 |
|
| 120 |
P |
L |
-0.7598 |
|
| 121 |
S |
L |
-2.0763 |
|
| 122 |
D |
L |
-3.5785 |
|
| 123 |
E |
L |
-3.8705 |
|
| 124 |
Q |
L |
-3.4481 |
|
| 125 |
L |
L |
-3.1811 |
|
| 126 |
K |
L |
-3.3473 |
|
| 127 |
S |
L |
-2.2852 |
|
| 128 |
G |
L |
-1.7615 |
|
| 129 |
T |
L |
-1.5668 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
-0.1098 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.8367 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5574 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.9648 |
|
| 138 |
N |
L |
-1.8810 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
-1.0551 |
|
| 141 |
P |
L |
-1.4888 |
|
| 142 |
R |
L |
-2.7004 |
|
| 143 |
E |
L |
-2.8851 |
|
| 144 |
A |
L |
-2.1042 |
|
| 145 |
K |
L |
-2.2886 |
|
| 146 |
V |
L |
-0.8836 |
|
| 147 |
Q |
L |
-0.3694 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.7916 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-2.2651 |
|
| 152 |
N |
L |
-1.7272 |
|
| 153 |
A |
L |
-0.5484 |
|
| 154 |
L |
L |
0.5869 |
|
| 155 |
Q |
L |
-0.1224 |
|
| 156 |
S |
L |
-0.3574 |
|
| 157 |
G |
L |
-0.8535 |
|
| 158 |
N |
L |
-1.0183 |
|
| 159 |
S |
L |
-1.4019 |
|
| 160 |
Q |
L |
-2.2836 |
|
| 161 |
E |
L |
-2.4763 |
|
| 162 |
S |
L |
-1.3551 |
|
| 163 |
V |
L |
-0.9862 |
|
| 164 |
T |
L |
-1.4504 |
|
| 165 |
E |
L |
-2.2708 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.5959 |
|
| 168 |
S |
L |
-2.6141 |
|
| 169 |
K |
L |
-2.9408 |
|
| 170 |
D |
L |
-2.2879 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-1.1803 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.5886 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5165 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.5388 |
|
| 181 |
L |
L |
-0.7115 |
|
| 182 |
S |
L |
-1.3413 |
|
| 183 |
K |
L |
-2.4861 |
|
| 184 |
A |
L |
-1.9377 |
|
| 185 |
D |
L |
-2.4500 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.6946 |
|
| 188 |
K |
L |
-3.5953 |
|
| 189 |
H |
L |
-3.0181 |
|
| 190 |
K |
L |
-2.7728 |
|
| 191 |
V |
L |
-1.2403 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
-0.9630 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.5523 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.0205 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.6065 |
|
| 200 |
G |
L |
-0.2730 |
|
| 201 |
L |
L |
-0.2332 |
|
| 202 |
S |
L |
-0.4771 |
|
| 203 |
S |
L |
-0.4220 |
|
| 204 |
P |
L |
-0.4666 |
|
| 205 |
V |
L |
0.0743 |
|
| 206 |
T |
L |
-0.3687 |
|
| 207 |
K |
L |
-0.5692 |
|
| 208 |
S |
L |
-0.2814 |
|
| 209 |
F |
L |
0.0000 |
|
| 210 |
N |
L |
-1.6338 |
|
| 211 |
R |
L |
-2.3663 |
|
| 212 |
G |
L |
-2.0580 |
|
| 213 |
E |
L |
-2.1237 |
|
| 214 |
C |
L |
-0.4450 |
|