| Chain sequence(s) |
A: GPMDASVEEEGVRRALDDFAVGEYNKASNDMMYHHSRACCQVVRRARKQIVAGVNYFLDVELCCRTTCCTKTQLDNNCCPPFHDQQPHHLKRKAFCSFQQIYAVPWQGTMTLSKSTCQDA B: GPMDASVEEEGVRRALDFAVGEYNKASNDMMYHHSRRACCQVVRRARKQIVAGVNYFLDVELCCCRTTCTKTQPNNCPFHDQPHHLKRKAFFCSFQIYAVPWQGTMTLSKSTCQDA |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 12 | G | A | -0.2919 | |
| 13 | P | A | -0.3015 | |
| 14 | M | A | -0.2401 | |
| 15 | D | A | -1.9929 | |
| 16 | A | A | -1.6642 | |
| 17 | S | A | -2.0382 | |
| 18 | V | A | 0.0000 | |
| 19 | E | A | -2.7192 | |
| 20 | E | A | -2.7425 | |
| 21 | E | A | -3.2388 | |
| 22 | G | A | -2.3952 | |
| 23 | V | A | 0.0000 | |
| 24 | R | A | -2.8187 | |
| 25 | R | A | -3.0076 | |
| 26 | A | A | 0.0000 | |
| 27 | L | A | 0.0000 | |
| 28 | D | A | -2.2173 | |
| 29 | F | A | -0.9998 | |
| 30 | A | A | 0.0000 | |
| 31 | V | A | -0.7054 | |
| 32 | G | A | -1.0653 | |
| 33 | E | A | -1.2095 | |
| 34 | Y | A | -0.6752 | |
| 35 | N | A | 0.0000 | |
| 36 | K | A | -2.1764 | |
| 37 | A | A | -1.2083 | |
| 38 | S | A | -1.1104 | |
| 39 | N | A | -1.4010 | |
| 40 | D | A | -0.6881 | |
| 41 | M | A | 0.5503 | |
| 42 | Y | A | 0.2496 | |
| 43 | H | A | -0.4478 | |
| 44 | S | A | 0.0000 | |
| 45 | R | A | -0.8451 | |
| 46 | A | A | -0.4839 | |
| 47 | C | A | 0.0000 | |
| 48 | Q | A | -0.4079 | |
| 49 | V | A | 0.0000 | |
| 50 | V | A | -0.1679 | |
| 51 | R | A | -1.8461 | |
| 52 | A | A | 0.0000 | |
| 53 | R | A | -1.5946 | |
| 54 | K | A | -0.3758 | |
| 55 | Q | A | 0.5446 | |
| 56 | I | A | 2.2419 | |
| 57 | V | A | 1.6876 | |
| 58 | A | A | 0.9027 | |
| 59 | G | A | 0.0000 | |
| 60 | V | A | 0.0000 | |
| 61 | N | A | 0.3820 | |
| 62 | Y | A | 0.0000 | |
| 63 | F | A | -0.7871 | |
| 64 | L | A | 0.0000 | |
| 65 | D | A | -0.4681 | |
| 66 | V | A | 0.0000 | |
| 67 | E | A | -0.5797 | |
| 68 | L | A | 0.0000 | |
| 69 | C | A | 0.0000 | |
| 70 | R | A | -0.9775 | |
| 71 | T | A | 0.0000 | |
| 72 | T | A | -0.6843 | |
| 73 | C | A | 0.0000 | |
| 74 | T | A | -0.1319 | |
| 75 | K | A | -0.7566 | |
| 76 | T | A | -0.7011 | |
| 77 | Q | A | -1.0810 | |
| 80 | L | A | 0.6725 | |
| 81 | D | A | -0.4383 | |
| 82 | N | A | -0.5319 | |
| 83 | C | A | 0.0000 | |
| 84 | P | A | 0.0000 | |
| 85 | F | A | 0.0000 | |
| 86 | H | A | 0.0000 | |
| 87 | D | A | -0.8013 | |
| 88 | Q | A | -1.2633 | |
| 89 | P | A | -1.3816 | |
| 90 | H | A | -1.8094 | |
| 91 | L | A | -1.2639 | |
| 92 | K | A | 0.0000 | |
| 93 | R | A | -3.0234 | |
| 94 | K | A | -2.3869 | |
| 95 | A | A | -1.6652 | |
| 96 | F | A | -0.4785 | |
| 97 | C | A | 0.0000 | |
| 98 | S | A | -0.5913 | |
| 99 | F | A | 0.0000 | |
| 100 | Q | A | -1.0003 | |
| 101 | I | A | 0.0000 | |
| 102 | Y | A | 0.3526 | |
| 103 | A | A | 0.0000 | |
| 104 | V | A | 0.0000 | |
| 105 | P | A | -0.1872 | |
| 106 | W | A | 0.3280 | |
| 107 | Q | A | -0.9223 | |
| 108 | G | A | -0.7535 | |
| 109 | T | A | -0.3481 | |
| 110 | M | A | -0.1749 | |
| 111 | T | A | -0.0708 | |
| 112 | L | A | -0.4272 | |
| 113 | S | A | -0.9623 | |
| 114 | K | A | -1.9006 | |
| 115 | S | A | -1.1064 | |
| 116 | T | A | -0.6173 | |
| 117 | C | A | -0.5150 | |
| 118 | Q | A | -2.0275 | |
| 119 | D | A | -2.7232 | |
| 120 | A | A | -1.3991 | |
| 12 | G | B | -0.1419 | |
| 13 | P | B | -0.4052 | |
| 14 | M | B | -0.5788 | |
| 15 | D | B | -2.0814 | |
| 16 | A | B | 0.0000 | |
| 17 | S | B | -1.7994 | |
| 18 | V | B | 0.0000 | |
| 19 | E | B | -2.5127 | |
| 20 | E | B | -2.5910 | |
| 21 | E | B | -3.1605 | |
| 22 | G | B | -2.2967 | |
| 23 | V | B | 0.0000 | |
| 24 | R | B | -2.5300 | |
| 25 | R | B | -2.6862 | |
| 26 | A | B | 0.0000 | |
| 27 | L | B | 0.0000 | |
| 28 | D | B | -1.2518 | |
| 29 | F | B | -0.4601 | |
| 30 | A | B | 0.0000 | |
| 31 | V | B | 0.0000 | |
| 32 | G | B | -0.7673 | |
| 33 | E | B | -0.9722 | |
| 34 | Y | B | -0.5590 | |
| 35 | N | B | 0.0000 | |
| 36 | K | B | -2.1420 | |
| 37 | A | B | -1.1831 | |
| 38 | S | B | -1.0599 | |
| 39 | N | B | -1.3523 | |
| 40 | D | B | -0.6863 | |
| 41 | M | B | 0.5558 | |
| 42 | Y | B | 0.2033 | |
| 43 | H | B | -0.5331 | |
| 44 | S | B | 0.0000 | |
| 45 | R | B | -0.6929 | |
| 46 | A | B | 0.0000 | |
| 47 | C | B | 0.0000 | |
| 48 | Q | B | -0.3174 | |
| 49 | V | B | 0.0000 | |
| 50 | V | B | 0.4400 | |
| 51 | R | B | -1.3267 | |
| 52 | A | B | 0.0000 | |
| 53 | R | B | -1.6986 | |
| 54 | K | B | -0.4783 | |
| 55 | Q | B | 0.4744 | |
| 56 | I | B | 2.2741 | |
| 57 | V | B | 1.8138 | |
| 58 | A | B | 0.9997 | |
| 59 | G | B | 0.0000 | |
| 60 | V | B | 0.0000 | |
| 61 | N | B | 0.4436 | |
| 62 | Y | B | 0.0000 | |
| 63 | F | B | -0.8880 | |
| 64 | L | B | 0.0000 | |
| 65 | D | B | -0.4434 | |
| 66 | V | B | 0.0000 | |
| 67 | E | B | -0.7142 | |
| 68 | L | B | 0.0000 | |
| 69 | C | B | 0.0000 | |
| 70 | R | B | -1.0588 | |
| 71 | T | B | 0.0000 | |
| 72 | T | B | 0.0000 | |
| 73 | C | B | -0.7414 | |
| 74 | T | B | -0.4035 | |
| 75 | K | B | -1.0997 | |
| 76 | T | B | -0.9720 | |
| 77 | Q | B | -1.7994 | |
| 78 | P | B | -1.5677 | |
| 79 | N | B | -1.8586 | |
| 82 | N | B | -1.3834 | |
| 83 | C | B | 0.0000 | |
| 84 | P | B | -0.9728 | |
| 85 | F | B | 0.0000 | |
| 86 | H | B | 0.0000 | |
| 87 | D | B | -1.3787 | |
| 88 | Q | B | -1.6236 | |
| 89 | P | B | -1.6498 | |
| 90 | H | B | -1.9091 | |
| 91 | L | B | -1.3926 | |
| 92 | K | B | -1.9146 | |
| 93 | R | B | -3.3245 | |
| 94 | K | B | -2.8227 | |
| 95 | A | B | -2.2026 | |
| 97 | C | B | -0.4917 | |
| 98 | S | B | -0.6778 | |
| 99 | F | B | 0.0000 | |
| 100 | Q | B | -0.9670 | |
| 101 | I | B | 0.0000 | |
| 102 | Y | B | 0.4336 | |
| 103 | A | B | 0.0000 | |
| 104 | V | B | 0.0000 | |
| 105 | P | B | -0.1877 | |
| 106 | W | B | 0.3373 | |
| 107 | Q | B | -0.9128 | |
| 108 | G | B | -0.7483 | |
| 109 | T | B | -0.3378 | |
| 110 | M | B | -0.0888 | |
| 111 | T | B | 0.0339 | |
| 112 | L | B | -0.2500 | |
| 113 | S | B | -0.8491 | |
| 114 | K | B | -1.8252 | |
| 115 | S | B | -1.0154 | |
| 116 | T | B | -0.7072 | |
| 117 | C | B | -0.9043 | |
| 118 | Q | B | -2.3195 | |
| 119 | D | B | -2.9826 | |
| 120 | A | B | -1.6266 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine