Project name: d442fece5e56eb2

Chain sequence(s)	A: EDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.0346
• Maximal score value: 1.3889
• Average score: -1.2405
• Total score value: -157.5402

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1079	E	A	-2.7821
1080	D	A	-2.8458
1081	S	A	-1.8755
1082	P	A	-1.3753
1083	L	A	-1.1765
1084	D	A	-1.9993
1085	A	A	-1.3382
1086	L	A	-0.8149
1087	D	A	-1.1029
1088	L	A	0.0000
1089	V	A	0.0000
1090	W	A	0.0000
1091	A	A	0.0000
1092	K	A	-0.9008
1093	C	A	-0.9465
1094	R	A	-1.8090
1095	G	A	-0.7833
1096	Y	A	0.2286
1097	P	A	-0.1975
1098	S	A	0.0000
1099	Y	A	0.0000
1100	P	A	0.0000
1101	A	A	0.0000
1102	L	A	0.0000
1103	I	A	0.0000
1104	I	A	0.0000
1105	D	A	-1.5268
1106	P	A	-1.1189
1107	K	A	-2.1303
1108	M	A	0.0000
1109	P	A	-1.7519
1110	R	A	-2.1830
1111	E	A	-2.3506
1112	G	A	-0.8397
1113	M	A	0.3329
1114	F	A	1.3889
1115	H	A	-0.2636
1116	H	A	-1.2998
1117	G	A	-0.6773
1118	V	A	-0.4139
1119	P	A	0.4283
1120	I	A	0.0000
1121	P	A	0.1009
1122	V	A	-0.3895
1123	P	A	0.0000
1124	P	A	-0.2424
1125	L	A	-0.0321
1126	E	A	-1.4475
1127	V	A	-0.6689
1128	L	A	-1.1879
1129	K	A	-2.1659
1130	L	A	-1.0564
1131	G	A	0.0000
1132	E	A	-3.1949
1133	Q	A	-3.1032
1134	M	A	-2.6122
1135	T	A	-3.3225
1136	Q	A	-4.0154
1137	E	A	-3.7779
1138	A	A	-3.0549
1139	R	A	-4.0346
1140	E	A	-3.7266
1141	H	A	-2.6423
1142	L	A	0.0000
1143	Y	A	-0.8150
1144	L	A	0.0000
1145	V	A	0.0000
1146	L	A	0.0000
1147	F	A	0.0000
1148	F	A	0.0000
1149	D	A	-1.6236
1150	N	A	-2.4517
1151	K	A	-2.7829
1152	R	A	-2.1048
1153	T	A	-1.1693
1154	W	A	-0.3790
1155	Q	A	-0.1782
1156	W	A	0.0000
1157	L	A	0.0000
1158	P	A	-1.0657
1159	R	A	-1.5249
1160	T	A	-1.1864
1161	K	A	-1.0384
1162	L	A	0.0000
1163	V	A	-0.3294
1164	P	A	0.0645
1165	L	A	0.0000
1166	G	A	-0.2467
1167	V	A	0.7805
1168	N	A	-1.3644
1169	Q	A	-2.7215
1170	D	A	-3.3649
1171	L	A	-2.1316
1172	D	A	0.0000
1173	K	A	-3.2563
1174	E	A	-2.8422
1175	K	A	-1.7462
1176	M	A	0.0000
1177	L	A	-0.6087
1178	E	A	-0.9550
1179	G	A	0.0000
1180	R	A	-2.6196
1181	K	A	-3.2153
1182	S	A	-2.4105
1183	N	A	-2.8156
1184	I	A	-1.7318
1185	R	A	-2.3158
1186	K	A	-2.4340
1187	S	A	-1.3929
1188	V	A	0.0000
1189	Q	A	-1.3759
1190	I	A	-0.6193
1191	A	A	0.0000
1192	Y	A	-0.8437
1193	H	A	-1.3401
1194	R	A	-1.4742
1195	A	A	0.0000
1196	L	A	-1.1345
1197	Q	A	-2.4739
1198	H	A	-1.9888
1199	R	A	-2.2338
1200	S	A	-2.6657
1201	K	A	-3.4467
1202	V	A	-2.3194
1203	Q	A	-3.0007
1204	G	A	-2.7897
1205	E	A	-3.1576