Project name: d451070ec360378

Chain sequence(s)	H: QVQLQESGPGLVQPSETLSLTCTVSGGSVSSGDYYWTWIRQSPGQGLEWIGHIYYSGNTNYNPSLRSRLTISIDTSRTQFSLQLSSVTAADTAIYYCVRDRVTGAFDIWGQGTMVTVSS; L: DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQRPGRAPRLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYFCQHFDHLPLAFGGGTRVEIR
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9702
• Maximal score value: 1.0044
• Average score: -0.6228
• Total score value: -140.7548

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.6621
2	V	H	0.0000
3	Q	H	-2.0745
4	L	H	0.0000
5	Q	H	-1.8537
6	E	H	0.0000
7	S	H	-0.6573
8	G	H	-0.5016
9	P	H	-0.1383
11	G	H	0.3439
12	L	H	0.8186
13	V	H	0.0000
14	Q	H	-1.2165
15	P	H	-1.1756
16	S	H	-1.4781
17	E	H	-2.2915
18	T	H	-1.4670
19	L	H	0.0000
20	S	H	-0.8952
21	L	H	0.0000
22	T	H	-0.5868
23	C	H	0.0000
24	T	H	-1.1079
25	V	H	0.0000
26	S	H	-1.5051
27	G	H	-1.3500
28	G	H	-1.0650
29	S	H	-0.8223
30	V	H	0.0000
31	S	H	-0.2716
34	S	H	-0.5111
35	G	H	-0.6594
36	D	H	-1.4427
37	Y	H	-0.2665
38	Y	H	0.3093
39	W	H	0.0000
40	T	H	0.0000
41	W	H	0.0000
42	I	H	0.0000
43	R	H	0.0000
44	Q	H	-0.3585
45	S	H	-0.5829
46	P	H	-0.9023
47	G	H	-1.3026
48	Q	H	-1.7575
49	G	H	-1.2476
50	L	H	0.0000
51	E	H	-0.6291
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	H	H	0.0000
56	I	H	0.0000
57	Y	H	0.0477
58	Y	H	0.4511
59	S	H	-0.2381
63	G	H	-0.7065
64	N	H	-1.4395
65	T	H	-0.8664
66	N	H	-0.9602
67	Y	H	-0.7149
68	N	H	-0.6955
69	P	H	-0.9095
70	S	H	-0.8097
71	L	H	0.0000
72	R	H	-1.8427
74	S	H	-1.1995
75	R	H	-1.2081
76	L	H	0.0000
77	T	H	-0.7692
78	I	H	0.0000
79	S	H	-0.3325
80	I	H	-0.1630
81	D	H	-1.0039
82	T	H	-0.8779
83	S	H	-1.3453
84	R	H	-2.1824
85	T	H	-1.3820
86	Q	H	-1.1291
87	F	H	0.0000
88	S	H	-0.4273
89	L	H	0.0000
90	Q	H	-0.9307
91	L	H	0.0000
92	S	H	-1.1784
93	S	H	-1.2497
94	V	H	0.0000
95	T	H	-0.5944
96	A	H	-0.1315
97	A	H	-0.2001
98	D	H	0.0000
99	T	H	0.3261
100	A	H	0.0000
101	I	H	0.7186
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	V	H	0.0000
106	R	H	-0.2423
107	D	H	0.0000
108	R	H	-0.3112
109	V	H	0.2584
110	T	H	0.0449
113	G	H	0.0000
114	A	H	0.0000
115	F	H	0.0000
116	D	H	0.0000
117	I	H	-0.5431
118	W	H	-0.9377
119	G	H	0.0000
120	Q	H	-2.0223
121	G	H	-0.8709
122	T	H	-0.0485
123	M	H	1.0044
124	V	H	0.0000
125	T	H	0.4341
126	V	H	0.0000
127	S	H	-0.2421
128	S	H	-0.4125
1	D	L	-2.2955
2	I	L	0.0000
3	Q	L	-2.0844
4	M	L	0.0000
5	T	L	-1.0356
6	Q	L	0.0000
7	S	L	-0.4710
8	P	L	-0.6485
9	S	L	-0.9392
10	S	L	-1.3641
11	L	L	-1.0755
12	S	L	-1.2287
13	A	L	-1.1730
14	S	L	-0.8800
15	V	L	-0.1182
16	G	L	-0.6462
17	D	L	-1.4743
18	R	L	-2.2213
19	V	L	0.0000
20	T	L	-0.6139
21	I	L	0.0000
22	T	L	-0.7319
23	C	L	0.0000
24	Q	L	-2.1181
25	A	L	0.0000
26	S	L	-2.1428
27	Q	L	-2.9702
28	D	L	-2.9052
29	I	L	0.0000
36	S	L	-1.2708
37	N	L	-0.9673
38	Y	L	-0.2190
39	L	L	0.0000
40	N	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	-1.5013
45	R	L	-1.9182
46	P	L	-1.2376
47	G	L	-1.8089
48	R	L	-2.8061
49	A	L	-1.7383
50	P	L	0.0000
51	R	L	-1.5154
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	-0.3421
56	D	L	-0.8250
57	A	L	0.0000
65	S	L	-0.9822
66	N	L	-1.0884
67	L	L	-0.2509
68	E	L	-0.4611
69	T	L	-0.3475
70	G	L	-0.4240
71	V	L	-0.2785
72	P	L	-0.2980
74	S	L	-0.3961
75	R	L	-0.6857
76	F	L	0.0000
77	S	L	-0.4395
78	G	L	0.0000
79	S	L	-0.9699
80	G	L	-1.2073
83	S	L	-1.3312
84	G	L	-1.8603
85	T	L	-2.3233
86	D	L	-2.7025
87	F	L	0.0000
88	T	L	-0.7427
89	F	L	0.0000
90	T	L	-0.5893
91	I	L	0.0000
92	S	L	-1.2449
93	S	L	-1.0410
94	L	L	0.0000
95	Q	L	-0.8237
96	P	L	-1.1636
97	E	L	-1.8674
98	D	L	0.0000
99	I	L	-0.9745
100	A	L	0.0000
101	T	L	0.0000
102	Y	L	0.0000
103	F	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	H	L	0.0000
107	F	L	-0.0545
108	D	L	-1.0025
109	H	L	-0.9589
114	L	L	-0.4034
115	P	L	0.0000
116	L	L	0.0000
117	A	L	-0.6446
118	F	L	0.0000
119	G	L	0.0000
120	G	L	-1.1523
121	G	L	-0.9015
122	T	L	0.0000
123	R	L	-2.3904
124	V	L	0.0000
125	E	L	-2.2744
126	I	L	-1.2406
127	R	L	-1.8088