Project name: 6axp:B
Status: done
submitted: 2019-03-20 16:17:43, status changed: 2019-03-20 17:33:50
Settings
|
Chain sequence(s)
|
B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.9042
-
Maximal score value
-
2.3443
-
Average score
-
-0.5701
-
Total score value
-
-125.4187
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
B |
-1.3705 |
|
| 2 |
V |
B |
-0.6570 |
|
| 3 |
Q |
B |
-1.2216 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
K |
B |
-2.2043 |
|
| 6 |
Q |
B |
-1.2862 |
|
| 7 |
S |
B |
-0.8554 |
|
| 8 |
G |
B |
-1.0326 |
|
| 9 |
P |
B |
-0.4304 |
|
| 10 |
G |
B |
-0.4308 |
|
| 11 |
L |
B |
-0.1505 |
|
| 12 |
V |
B |
0.0000 |
|
| 13 |
Q |
B |
-1.6927 |
|
| 14 |
P |
B |
-1.5655 |
|
| 15 |
S |
B |
-1.6048 |
|
| 16 |
Q |
B |
-2.0087 |
|
| 17 |
S |
B |
-1.8985 |
|
| 18 |
L |
B |
0.0000 |
|
| 19 |
S |
B |
-0.9330 |
|
| 20 |
I |
B |
0.0000 |
|
| 21 |
T |
B |
-0.6060 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
T |
B |
-1.1409 |
|
| 24 |
V |
B |
0.0000 |
|
| 25 |
S |
B |
-1.1427 |
|
| 26 |
G |
B |
-0.9129 |
|
| 27 |
F |
B |
-0.5062 |
|
| 28 |
S |
B |
-0.8919 |
|
| 29 |
L |
B |
0.0000 |
|
| 30 |
T |
B |
-0.9078 |
|
| 31 |
N |
B |
-0.8979 |
|
| 32 |
Y |
B |
0.3001 |
|
| 33 |
G |
B |
0.0000 |
|
| 34 |
V |
B |
0.0000 |
|
| 35 |
H |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.2783 |
|
| 40 |
S |
B |
-0.9298 |
|
| 41 |
P |
B |
-1.1104 |
|
| 42 |
G |
B |
-1.6497 |
|
| 43 |
K |
B |
-2.0062 |
|
| 44 |
G |
B |
-0.6380 |
|
| 45 |
L |
B |
0.7935 |
|
| 46 |
E |
B |
0.0000 |
|
| 47 |
W |
B |
0.4564 |
|
| 48 |
L |
B |
0.0000 |
|
| 49 |
G |
B |
0.0000 |
|
| 50 |
V |
B |
0.0000 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
W |
B |
-0.5790 |
|
| 53 |
S |
B |
-0.6534 |
|
| 54 |
G |
B |
-1.2070 |
|
| 55 |
G |
B |
-1.6040 |
|
| 56 |
N |
B |
-1.9219 |
|
| 57 |
T |
B |
-1.4871 |
|
| 58 |
D |
B |
-1.4897 |
|
| 59 |
Y |
B |
-0.6529 |
|
| 60 |
N |
B |
-0.6155 |
|
| 61 |
T |
B |
-0.5048 |
|
| 62 |
P |
B |
-0.4698 |
|
| 63 |
F |
B |
0.0000 |
|
| 64 |
T |
B |
-0.6033 |
|
| 65 |
S |
B |
-0.7068 |
|
| 66 |
R |
B |
-1.3170 |
|
| 67 |
L |
B |
0.0000 |
|
| 68 |
S |
B |
-1.3601 |
|
| 69 |
I |
B |
0.0000 |
|
| 70 |
N |
B |
-1.7872 |
|
| 71 |
K |
B |
-1.4076 |
|
| 72 |
D |
B |
-1.7487 |
|
| 73 |
N |
B |
-2.1404 |
|
| 74 |
S |
B |
-1.6442 |
|
| 75 |
K |
B |
-2.3524 |
|
| 76 |
S |
B |
-1.5469 |
|
| 77 |
Q |
B |
-1.5264 |
|
| 78 |
V |
B |
0.0000 |
|
| 79 |
F |
B |
-0.3943 |
|
| 80 |
F |
B |
0.0000 |
|
| 81 |
K |
B |
-2.1383 |
|
| 82 |
M |
B |
0.0000 |
|
| 83 |
N |
B |
-2.2651 |
|
| 84 |
S |
B |
-1.6656 |
|
| 85 |
L |
B |
0.0000 |
|
| 86 |
Q |
B |
-2.0717 |
|
| 87 |
S |
B |
-1.5307 |
|
| 88 |
N |
B |
-2.0242 |
|
| 89 |
D |
B |
0.0000 |
|
| 90 |
T |
B |
-0.6656 |
|
| 91 |
A |
B |
0.0000 |
|
| 92 |
I |
B |
0.5222 |
|
| 93 |
Y |
B |
0.0000 |
|
| 94 |
Y |
B |
-0.0932 |
|
| 95 |
C |
B |
0.0000 |
|
| 96 |
A |
B |
0.0000 |
|
| 97 |
R |
B |
0.0000 |
|
| 98 |
A |
B |
0.0000 |
|
| 99 |
L |
B |
1.1023 |
|
| 100 |
T |
B |
0.9586 |
|
| 101 |
Y |
B |
1.7784 |
|
| 102 |
Y |
B |
1.4956 |
|
| 103 |
D |
B |
0.2483 |
|
| 104 |
Y |
B |
0.1638 |
|
| 105 |
E |
B |
-1.0469 |
|
| 106 |
F |
B |
0.0321 |
|
| 107 |
A |
B |
0.4356 |
|
| 108 |
Y |
B |
0.5211 |
|
| 109 |
W |
B |
0.1533 |
|
| 110 |
G |
B |
0.0000 |
|
| 111 |
Q |
B |
-1.4227 |
|
| 112 |
G |
B |
0.0000 |
|
| 113 |
T |
B |
0.0000 |
|
| 114 |
L |
B |
0.3564 |
|
| 115 |
V |
B |
0.0000 |
|
| 116 |
T |
B |
0.0000 |
|
| 117 |
V |
B |
0.0000 |
|
| 118 |
S |
B |
-0.5980 |
|
| 119 |
A |
B |
-0.4260 |
|
| 120 |
A |
B |
-0.3626 |
|
| 121 |
S |
B |
-0.5831 |
|
| 122 |
T |
B |
-0.8117 |
|
| 123 |
K |
B |
-1.3664 |
|
| 124 |
G |
B |
-1.6211 |
|
| 125 |
P |
B |
-0.7180 |
|
| 126 |
S |
B |
-0.0947 |
|
| 127 |
V |
B |
0.0000 |
|
| 128 |
F |
B |
1.0812 |
|
| 129 |
P |
B |
-0.0046 |
|
| 130 |
L |
B |
0.3836 |
|
| 131 |
A |
B |
-1.0571 |
|
| 132 |
P |
B |
0.0000 |
|
| 133 |
S |
B |
-1.3391 |
|
| 134 |
S |
B |
-1.2029 |
|
| 135 |
K |
B |
-1.8845 |
|
| 136 |
S |
B |
-0.9978 |
|
| 137 |
T |
B |
-1.0116 |
|
| 138 |
S |
B |
-0.9572 |
|
| 139 |
G |
B |
-0.8553 |
|
| 140 |
G |
B |
-0.9439 |
|
| 141 |
T |
B |
-0.6889 |
|
| 142 |
A |
B |
0.0000 |
|
| 143 |
A |
B |
-0.1936 |
|
| 144 |
L |
B |
0.0000 |
|
| 145 |
G |
B |
0.0000 |
|
| 146 |
C |
B |
0.0000 |
|
| 147 |
L |
B |
0.7348 |
|
| 148 |
V |
B |
0.0000 |
|
| 149 |
K |
B |
-0.3868 |
|
| 150 |
D |
B |
-0.8106 |
|
| 151 |
Y |
B |
0.0000 |
|
| 152 |
F |
B |
0.0000 |
|
| 153 |
P |
B |
0.0000 |
|
| 154 |
E |
B |
-0.0586 |
|
| 155 |
P |
B |
-0.5122 |
|
| 156 |
V |
B |
-0.7293 |
|
| 157 |
T |
B |
-0.6821 |
|
| 158 |
V |
B |
-0.4232 |
|
| 159 |
S |
B |
-0.3937 |
|
| 160 |
W |
B |
0.0000 |
|
| 161 |
N |
B |
-0.8218 |
|
| 162 |
S |
B |
-0.6633 |
|
| 163 |
G |
B |
-0.5831 |
|
| 164 |
A |
B |
-0.2505 |
|
| 165 |
L |
B |
-0.0471 |
|
| 166 |
T |
B |
-0.2913 |
|
| 167 |
S |
B |
-0.3598 |
|
| 168 |
G |
B |
-0.4554 |
|
| 169 |
V |
B |
0.0353 |
|
| 170 |
H |
B |
-0.4001 |
|
| 171 |
T |
B |
0.2197 |
|
| 172 |
F |
B |
1.0474 |
|
| 173 |
P |
B |
0.7623 |
|
| 174 |
A |
B |
1.2521 |
|
| 175 |
V |
B |
2.3443 |
|
| 176 |
L |
B |
1.8759 |
|
| 177 |
Q |
B |
0.0741 |
|
| 178 |
S |
B |
-0.2149 |
|
| 179 |
S |
B |
-0.4264 |
|
| 180 |
G |
B |
0.0100 |
|
| 181 |
L |
B |
0.0625 |
|
| 182 |
Y |
B |
0.6505 |
|
| 183 |
S |
B |
0.0000 |
|
| 184 |
L |
B |
0.0000 |
|
| 185 |
S |
B |
0.7109 |
|
| 186 |
S |
B |
0.0000 |
|
| 187 |
V |
B |
0.4865 |
|
| 188 |
V |
B |
0.0000 |
|
| 189 |
T |
B |
-0.2106 |
|
| 190 |
V |
B |
0.0000 |
|
| 191 |
P |
B |
-0.5468 |
|
| 192 |
S |
B |
-0.5951 |
|
| 193 |
S |
B |
-0.6137 |
|
| 194 |
S |
B |
-0.6764 |
|
| 195 |
L |
B |
-0.8410 |
|
| 196 |
G |
B |
-0.9933 |
|
| 197 |
T |
B |
-0.8128 |
|
| 198 |
Q |
B |
-1.3930 |
|
| 199 |
T |
B |
-1.2681 |
|
| 200 |
Y |
B |
0.0000 |
|
| 201 |
I |
B |
-1.4776 |
|
| 202 |
C |
B |
0.0000 |
|
| 203 |
N |
B |
-1.4789 |
|
| 204 |
V |
B |
0.0000 |
|
| 205 |
N |
B |
-2.2786 |
|
| 206 |
H |
B |
0.0000 |
|
| 207 |
K |
B |
-2.9037 |
|
| 208 |
P |
B |
-1.6659 |
|
| 209 |
S |
B |
-1.9079 |
|
| 210 |
N |
B |
-2.6586 |
|
| 211 |
T |
B |
-2.2134 |
|
| 212 |
K |
B |
-2.7466 |
|
| 213 |
V |
B |
-1.6113 |
|
| 214 |
D |
B |
-2.2044 |
|
| 215 |
K |
B |
-1.9339 |
|
| 216 |
R |
B |
-2.5765 |
|
| 217 |
V |
B |
0.0000 |
|
| 218 |
E |
B |
-2.9042 |
|
| 219 |
P |
B |
-1.8855 |
|
| 220 |
K |
B |
-2.2358 |
|