Project name: 5csz:H

Chain sequence(s)	H: VELVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAINASGTRTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGKGYVRYFDVWGQGTLVTVSSASTKGPSVFPLAPSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7993
• Maximal score value: 2.4371
• Average score: -0.5153
• Total score value: -109.7579

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	H	0.7874
3	E	H	-0.8715
4	L	H	0.0000
5	V	H	0.2980
6	E	H	0.0000
7	S	H	-0.5186
8	G	H	-0.8924
9	G	H	-0.4913
10	G	H	-0.2710
11	L	H	-0.0243
12	V	H	-0.5737
13	Q	H	-1.5169
14	P	H	-1.5232
15	G	H	-1.2373
16	G	H	0.0000
17	S	H	-1.1934
18	L	H	-1.0807
19	R	H	-2.2301
20	L	H	0.0000
21	S	H	-0.5263
22	C	H	0.0000
23	A	H	-0.4991
24	A	H	0.0000
25	S	H	-0.4561
26	G	H	-0.1302
27	F	H	0.0691
28	T	H	-0.0929
29	F	H	0.0000
30	S	H	-0.8329
31	S	H	-0.2658
32	Y	H	-0.0636
33	A	H	-0.1311
34	M	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.4540
40	A	H	-1.0921
41	P	H	-1.0393
42	G	H	-1.4146
43	K	H	-2.0960
44	G	H	-0.9204
45	L	H	0.5692
46	E	H	-0.2299
47	W	H	0.4670
48	V	H	0.0000
49	S	H	0.0000
50	A	H	-0.0855
51	I	H	0.0000
52	N	H	-0.7706
53	A	H	-0.6695
54	S	H	-0.9182
55	G	H	-1.1526
56	T	H	-1.2256
57	R	H	-1.9841
58	T	H	-0.8320
59	Y	H	-0.3686
60	Y	H	-0.6364
61	A	H	-1.2132
62	D	H	-2.3847
63	S	H	-1.7444
64	V	H	0.0000
65	K	H	-2.5362
66	G	H	-1.7428
67	R	H	-1.4645
68	F	H	0.0000
69	T	H	-0.8905
70	I	H	0.0000
71	S	H	-0.6901
72	R	H	-1.0334
73	D	H	-1.5523
74	N	H	-1.7400
75	S	H	-1.6178
76	K	H	-2.4807
77	N	H	-1.9897
78	T	H	-1.1559
79	L	H	0.0000
80	Y	H	-0.5966
81	L	H	0.0000
82	Q	H	-1.5279
83	M	H	0.0000
84	N	H	-1.2977
85	S	H	-1.0624
86	L	H	0.0000
87	R	H	-2.0507
88	A	H	-1.6046
89	E	H	-2.1603
90	D	H	0.0000
91	T	H	-0.7036
92	A	H	0.0000
93	V	H	0.4472
94	Y	H	0.0000
95	Y	H	0.4419
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	G	H	0.0000
100	K	H	-0.2957
101	G	H	-0.4283
109	Y	H	1.0345
110	V	H	0.4892
111	R	H	-0.8165
112	Y	H	0.6384
113	F	H	0.6940
114	D	H	-0.1986
115	V	H	0.3401
116	W	H	0.3053
117	G	H	-0.3545
118	Q	H	-1.0117
119	G	H	0.0000
120	T	H	0.0346
121	L	H	0.3744
122	V	H	0.0000
123	T	H	-0.3910
124	V	H	0.0000
125	S	H	-0.9585
126	S	H	-0.7265
127	A	H	-0.4847
128	S	H	-0.6024
129	T	H	-0.6112
130	K	H	-1.1718
131	G	H	-1.4322
132	P	H	0.0000
133	S	H	-0.0746
134	V	H	0.0000
135	F	H	0.9018
136	P	H	-0.0264
137	L	H	0.3212
138	A	H	-0.8362
139	P	H	0.0000
140	S	H	-0.6681
148	T	H	-0.2540
149	A	H	-0.1884
150	A	H	0.0630
151	L	H	0.0000
152	G	H	0.0000
153	C	H	0.0000
154	L	H	0.6913
155	V	H	0.0000
156	K	H	-0.2011
157	D	H	-0.5503
158	Y	H	0.0000
159	F	H	0.0000
160	P	H	0.0000
161	E	H	-0.5129
162	P	H	-0.7694
163	V	H	-0.7868
164	T	H	-0.6537
165	V	H	-0.3420
166	S	H	-0.5112
167	W	H	0.0000
168	N	H	-0.7869
169	S	H	-0.6716
170	G	H	-0.5343
171	A	H	-0.2570
172	L	H	-0.0122
173	T	H	-0.2979
174	S	H	-0.2964
175	G	H	-0.3155
176	V	H	-0.0916
177	H	H	-0.6145
178	T	H	0.0250
179	F	H	0.8234
180	P	H	0.6529
181	A	H	1.2028
182	V	H	2.4371
183	L	H	2.0064
184	Q	H	0.7024
185	S	H	0.1067
186	S	H	-0.1774
187	G	H	0.2386
188	L	H	0.3314
189	Y	H	0.8481
190	S	H	0.0000
191	L	H	0.0000
192	S	H	0.5716
193	S	H	0.0000
194	V	H	0.2901
195	V	H	0.0000
196	T	H	-0.2073
197	V	H	0.0000
198	P	H	-0.4984
199	S	H	-0.4623
200	S	H	-0.5246
201	S	H	-0.5664
202	L	H	-0.7266
203	G	H	-1.2396
204	T	H	-0.8313
205	Q	H	-1.1167
206	T	H	-1.0684
207	Y	H	0.0000
208	I	H	-1.3029
209	C	H	0.0000
210	N	H	-1.4794
211	V	H	0.0000
212	N	H	-2.1173
213	H	H	0.0000
214	K	H	-2.7993
215	P	H	-1.6214
216	S	H	-1.8427
217	N	H	-2.6331
218	T	H	-2.1091
219	K	H	-2.7304
220	V	H	-1.5798
221	D	H	-2.4506
222	K	H	-2.0721
223	K	H	-2.4075
224	V	H	0.0000
225	E	H	-2.6777
226	P	H	-1.8174
227	K	H	-2.3191
228	S	H	-1.2948