Project name: 6b3s:L
Status: done
submitted: 2019-03-20 20:42:49, status changed: 2019-03-20 20:53:43
Settings
|
Chain sequence(s)
|
L: EIVMTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCHQYGSTPLTFGGGTKAEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4786
-
Maximal score value
-
2.169
-
Average score
-
-0.7897
-
Total score value
-
-168.208
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
L |
-1.3305 |
|
| 2 |
I |
L |
-0.0370 |
|
| 3 |
V |
L |
1.0054 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.4146 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.6685 |
|
| 8 |
P |
L |
-0.4502 |
|
| 9 |
A |
L |
-0.4539 |
|
| 10 |
T |
L |
-0.4411 |
|
| 11 |
L |
L |
-0.2390 |
|
| 12 |
S |
L |
-0.4930 |
|
| 13 |
L |
L |
-0.8405 |
|
| 14 |
S |
L |
-1.2863 |
|
| 15 |
P |
L |
-1.6483 |
|
| 16 |
G |
L |
-1.8098 |
|
| 17 |
E |
L |
-2.3279 |
|
| 18 |
R |
L |
-2.5901 |
|
| 19 |
A |
L |
0.0000 |
|
| 20 |
T |
L |
-0.5955 |
|
| 21 |
L |
L |
0.0000 |
|
| 22 |
S |
L |
-0.8545 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.4174 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-1.1013 |
|
| 27 |
Q |
L |
-1.7275 |
|
| 28 |
S |
L |
-1.3076 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
S |
L |
-0.5972 |
|
| 31 |
S |
L |
-0.1462 |
|
| 32 |
Y |
L |
0.5941 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.1619 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.2825 |
|
| 39 |
K |
L |
-1.7196 |
|
| 40 |
P |
L |
-1.3325 |
|
| 41 |
G |
L |
-1.3521 |
|
| 42 |
Q |
L |
-1.9433 |
|
| 43 |
A |
L |
-1.2122 |
|
| 44 |
P |
L |
-1.1642 |
|
| 45 |
R |
L |
-1.4793 |
|
| 46 |
L |
L |
-0.3338 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.3766 |
|
| 50 |
D |
L |
-1.0290 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-1.3526 |
|
| 53 |
N |
L |
-2.1577 |
|
| 54 |
R |
L |
-2.0823 |
|
| 55 |
A |
L |
-1.0780 |
|
| 56 |
T |
L |
-0.7086 |
|
| 57 |
G |
L |
-0.6694 |
|
| 58 |
I |
L |
0.0000 |
|
| 59 |
P |
L |
-0.5212 |
|
| 60 |
A |
L |
-0.4888 |
|
| 61 |
R |
L |
-0.9361 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.8414 |
|
| 64 |
G |
L |
-0.8498 |
|
| 65 |
S |
L |
-0.9384 |
|
| 66 |
G |
L |
-1.2076 |
|
| 67 |
S |
L |
-0.8566 |
|
| 68 |
G |
L |
-1.1074 |
|
| 69 |
T |
L |
-1.8370 |
|
| 70 |
D |
L |
-2.3434 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7747 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6117 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.4700 |
|
| 77 |
S |
L |
-1.8053 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
E |
L |
-2.0820 |
|
| 80 |
P |
L |
-1.6360 |
|
| 81 |
E |
L |
-2.2846 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-0.7757 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
V |
L |
-0.4916 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.2609 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
H |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
Y |
L |
1.0327 |
|
| 92 |
G |
L |
0.1347 |
|
| 93 |
S |
L |
-0.2257 |
|
| 94 |
T |
L |
-0.1060 |
|
| 95 |
P |
L |
-0.1074 |
|
| 96 |
L |
L |
1.4759 |
|
| 97 |
T |
L |
1.3990 |
|
| 98 |
F |
L |
2.1690 |
|
| 99 |
G |
L |
0.5644 |
|
| 100 |
G |
L |
-0.0424 |
|
| 101 |
G |
L |
-0.2307 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.0754 |
|
| 104 |
A |
L |
0.0000 |
|
| 105 |
E |
L |
-0.6839 |
|
| 106 |
I |
L |
-0.6456 |
|
| 107 |
K |
L |
-1.2265 |
|
| 108 |
R |
L |
-0.9160 |
|
| 109 |
T |
L |
-0.0991 |
|
| 110 |
V |
L |
0.4909 |
|
| 111 |
A |
L |
-0.0387 |
|
| 112 |
A |
L |
-0.1718 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1426 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.2462 |
|
| 117 |
I |
L |
1.2478 |
|
| 118 |
F |
L |
1.4372 |
|
| 119 |
P |
L |
-0.0268 |
|
| 120 |
P |
L |
-0.8559 |
|
| 121 |
S |
L |
-1.8579 |
|
| 122 |
D |
L |
-3.3250 |
|
| 123 |
E |
L |
-3.4786 |
|
| 124 |
Q |
L |
-2.6142 |
|
| 125 |
L |
L |
-2.6049 |
|
| 126 |
K |
L |
-3.0769 |
|
| 127 |
S |
L |
-1.9450 |
|
| 128 |
G |
L |
-1.3919 |
|
| 129 |
T |
L |
-1.2187 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0124 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7248 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5588 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6046 |
|
| 138 |
N |
L |
-1.2780 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.6757 |
|
| 142 |
R |
L |
-2.8345 |
|
| 143 |
E |
L |
-3.1745 |
|
| 144 |
A |
L |
-2.3162 |
|
| 145 |
K |
L |
-2.4697 |
|
| 146 |
V |
L |
-1.1766 |
|
| 147 |
Q |
L |
-0.7630 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.5963 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.9232 |
|
| 152 |
N |
L |
-1.5306 |
|
| 153 |
A |
L |
-0.2827 |
|
| 154 |
L |
L |
0.6983 |
|
| 155 |
Q |
L |
-0.1266 |
|
| 156 |
S |
L |
-0.4288 |
|
| 157 |
G |
L |
-0.9890 |
|
| 158 |
N |
L |
-0.9242 |
|
| 159 |
S |
L |
-1.4203 |
|
| 160 |
Q |
L |
-2.2874 |
|
| 161 |
E |
L |
-2.3433 |
|
| 162 |
S |
L |
-1.1852 |
|
| 163 |
V |
L |
-0.8372 |
|
| 164 |
T |
L |
-1.2721 |
|
| 165 |
E |
L |
-2.3823 |
|
| 166 |
Q |
L |
-2.1446 |
|
| 167 |
D |
L |
-2.4150 |
|
| 168 |
S |
L |
-1.9009 |
|
| 169 |
K |
L |
-2.3808 |
|
| 170 |
D |
L |
-1.8191 |
|
| 171 |
S |
L |
-1.9258 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-1.0720 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4364 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5975 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.4941 |
|
| 181 |
L |
L |
-0.6329 |
|
| 182 |
S |
L |
-1.0699 |
|
| 183 |
K |
L |
-2.1563 |
|
| 184 |
A |
L |
-1.8149 |
|
| 185 |
D |
L |
-2.4274 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.1891 |
|
| 188 |
K |
L |
-3.4620 |
|
| 189 |
H |
L |
-3.0300 |
|
| 190 |
K |
L |
-3.0690 |
|
| 191 |
V |
L |
-1.3987 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-1.0246 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2599 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.5520 |
|
| 200 |
G |
L |
-0.4167 |
|
| 201 |
L |
L |
-0.2515 |
|
| 202 |
S |
L |
-0.4714 |
|
| 203 |
S |
L |
-0.4773 |
|
| 204 |
P |
L |
-0.6307 |
|
| 205 |
V |
L |
-0.1554 |
|
| 206 |
T |
L |
-0.4686 |
|
| 207 |
K |
L |
-0.3974 |
|
| 208 |
S |
L |
-0.3295 |
|
| 209 |
F |
L |
-0.6129 |
|
| 210 |
N |
L |
-1.7625 |
|
| 211 |
R |
L |
-2.1779 |
|
| 212 |
G |
L |
-1.5598 |
|
| 213 |
A |
L |
-0.5974 |
|