Project name: 5vsh:A

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGFTFTDYTMDWVRYAPGKGLEWVADVNPNSGGSIYNQRFKGRFTLSVDRSKNTLYLQMNSLRRAEDTAVYYCARNLGPSFYFDYWGRGTLVTVSSASTKGPSVFPLAPCGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0601
• Maximal score value: 2.4093
• Average score: -0.4985
• Total score value: -106.6719

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.1242
2	V	A	-1.1468
3	Q	A	-1.2496
4	L	A	0.0000
5	V	A	0.9378
6	E	A	0.0000
7	S	A	-0.2821
8	G	A	-1.0105
9	G	A	-0.5790
10	G	A	-0.3059
11	L	A	-0.1565
12	V	A	0.0000
13	Q	A	-1.7475
14	P	A	-1.9168
15	G	A	-1.5545
16	G	A	0.0000
17	S	A	-1.3782
18	L	A	-1.2842
19	R	A	-2.2488
20	L	A	0.0000
21	S	A	-0.3868
22	C	A	0.0000
23	A	A	-0.1975
24	A	A	0.0000
25	S	A	-0.8653
26	G	A	-1.2675
27	F	A	-0.6665
28	T	A	-0.6137
29	F	A	0.0000
30	T	A	-1.7625
31	D	A	-1.7341
32	Y	A	-0.3703
33	T	A	-0.0959
34	M	A	0.0000
35	D	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	R	A	0.0000
39	Y	A	0.6405
40	A	A	0.0000
41	P	A	-0.7526
42	G	A	-1.2491
43	K	A	-1.7302
44	G	A	-0.4520
45	L	A	1.1055
46	E	A	0.3492
47	W	A	0.6443
48	V	A	0.0000
49	A	A	0.0000
50	D	A	0.0000
51	V	A	0.0000
52	N	A	-1.0720
53	P	A	0.0000
54	N	A	-2.2311
55	S	A	-1.3025
56	G	A	-1.2283
57	G	A	-0.4188
58	S	A	0.6135
59	I	A	1.5310
60	Y	A	-0.1546
61	N	A	-1.3089
62	Q	A	-2.5828
63	R	A	-3.0601
64	F	A	0.0000
65	K	A	-2.7137
66	G	A	-1.9632
67	R	A	-1.8843
68	F	A	0.0000
69	T	A	-0.8189
70	L	A	0.0000
71	S	A	-0.3979
72	V	A	-1.1702
73	D	A	-2.0876
74	R	A	-2.8092
75	S	A	-2.0570
76	K	A	-2.6995
77	N	A	-2.1601
78	T	A	0.0000
79	L	A	0.0000
80	Y	A	-0.6095
81	L	A	0.0000
82	Q	A	-1.6171
83	M	A	0.0000
84	N	A	-1.4540
85	S	A	-1.3116
86	L	A	0.0000
87	R	A	-2.9110
88	A	A	-1.9943
89	E	A	-2.4289
90	D	A	0.0000
91	T	A	-0.7062
92	A	A	0.0000
93	V	A	0.5872
94	Y	A	0.0000
95	Y	A	0.5237
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	N	A	0.0000
100	L	A	1.3572
101	G	A	0.4503
102	P	A	0.3158
103	S	A	0.9307
104	F	A	1.7090
105	Y	A	1.7419
106	F	A	0.8281
107	D	A	-0.5599
108	Y	A	0.2297
109	W	A	0.2714
110	G	A	-0.1993
111	R	A	-1.4017
112	G	A	0.0000
113	T	A	0.0000
114	L	A	0.1748
115	V	A	0.0000
116	T	A	-0.5308
117	V	A	0.0000
118	S	A	-0.8936
119	S	A	-0.7562
120	A	A	-0.5351
121	S	A	-0.6686
122	T	A	-0.8075
123	K	A	-1.6043
124	G	A	-1.7007
125	P	A	0.0000
126	S	A	-0.2135
127	V	A	0.0000
128	F	A	1.1088
129	P	A	0.1560
130	L	A	0.5007
131	A	A	-0.0397
132	P	A	-0.0236
133	C	A	0.4651
139	G	A	-0.7834
140	G	A	-0.8576
141	T	A	-0.5904
142	A	A	-0.3145
143	A	A	0.1153
144	L	A	0.0000
145	G	A	0.0000
146	C	A	0.0000
147	L	A	0.7514
148	V	A	0.0000
149	K	A	-0.4060
150	D	A	-0.7173
151	Y	A	0.0000
152	F	A	0.0000
153	P	A	0.0000
154	E	A	-0.4500
155	P	A	-0.7175
156	V	A	-0.4529
157	T	A	-0.5038
158	V	A	-0.1518
159	S	A	-0.3643
160	W	A	0.0000
161	N	A	-0.6994
162	S	A	-0.6711
163	G	A	-0.5692
164	A	A	-0.2360
165	L	A	0.0124
166	T	A	-0.2793
167	S	A	-0.3498
168	G	A	-0.4375
169	V	A	0.0053
170	H	A	-0.5053
171	T	A	0.0681
172	F	A	0.7573
173	P	A	0.6215
174	A	A	1.2099
175	V	A	2.4093
176	L	A	2.1071
177	Q	A	0.6156
178	S	A	0.0431
179	S	A	-0.2687
180	G	A	0.1579
181	L	A	0.1127
182	Y	A	0.7014
183	S	A	0.0000
184	L	A	0.0000
185	S	A	0.6025
186	S	A	0.0000
187	V	A	0.4240
188	V	A	0.0000
189	T	A	-0.2199
190	V	A	0.0000
191	P	A	-0.5175
192	S	A	-0.5420
193	S	A	-0.6426
194	S	A	-0.6080
195	L	A	-0.7185
196	G	A	-0.9951
197	T	A	-0.7820
198	Q	A	-1.1695
199	T	A	-1.1425
200	Y	A	0.0000
201	I	A	-1.3006
202	C	A	0.0000
203	N	A	-1.5396
204	V	A	0.0000
205	N	A	-1.8558
206	H	A	0.0000
207	K	A	-2.7473
208	P	A	-1.6867
209	S	A	-1.9410
210	N	A	-2.6333
211	T	A	-2.0623
212	K	A	-2.7611
213	V	A	-1.6654
214	D	A	-2.6422
215	K	A	-2.1495
216	K	A	-2.3763
217	V	A	0.0000
218	E	A	-2.2439
219	P	A	-1.0741