Project name: retro9

Chain sequence(s)	A: MEEPQSDLSTELPLSQETFSYLGKLLPEKLVLSPSLSPAAEAVDDLLLPEDAADWLESQAGAQGISEAPTLATSWTLSSSVPSQKTYPAPIVSVWASCILGQPSLSPTRTPLNLTCCFAGWQRPVQCSCGSPQHPRPAPVFTPWPSTRRQHMMEVVKHCPHLECRCDYSDCLDPPQHLIQIT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4612
• Maximal score value: 2.1916
• Average score: -0.2166
• Total score value: -39.4178

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	-0.4814
2	E	A	-2.0986
3	E	A	-1.7229
4	P	A	-0.9169
5	Q	A	-0.9307
6	S	A	-1.0605
7	D	A	-1.6450
8	L	A	-0.6060
9	S	A	-0.2938
10	T	A	-0.4530
11	E	A	0.0000
12	L	A	0.4666
13	P	A	0.0040
14	L	A	0.3297
15	S	A	-0.2010
16	Q	A	-0.8411
17	E	A	0.0000
18	T	A	0.0000
19	F	A	0.0000
20	S	A	0.0000
21	Y	A	0.0758
22	L	A	1.0088
23	G	A	0.0000
24	K	A	0.1328
25	L	A	0.0000
26	L	A	0.0000
27	P	A	0.1017
28	E	A	0.0892
29	K	A	0.1688
30	L	A	0.6641
31	V	A	1.3691
32	L	A	1.1324
33	S	A	0.3618
34	P	A	-0.3765
35	S	A	-0.8846
36	L	A	0.0000
37	S	A	0.0000
38	P	A	0.4879
39	A	A	0.0000
40	A	A	-1.2524
41	E	A	-1.7580
42	A	A	-0.2801
43	V	A	0.8125
44	D	A	0.0508
45	D	A	0.0000
46	L	A	0.0000
47	L	A	0.0000
48	L	A	-0.4271
49	P	A	-0.8273
50	E	A	-2.0481
51	D	A	-2.2620
52	A	A	-1.7773
53	A	A	-1.2824
54	D	A	-1.8743
55	W	A	-0.7255
56	L	A	-0.1852
57	E	A	-1.5369
58	S	A	0.0000
59	Q	A	-0.2599
60	A	A	-0.4121
61	G	A	0.0000
62	A	A	0.2769
63	Q	A	0.2692
64	G	A	0.0000
65	I	A	0.9671
66	S	A	-0.4097
67	E	A	-1.2367
68	A	A	0.0841
69	P	A	0.1208
70	T	A	0.7994
71	L	A	0.5466
72	A	A	0.0000
73	T	A	0.6798
74	S	A	0.2998
75	W	A	1.1738
76	T	A	1.1878
77	L	A	1.6264
78	S	A	0.7324
79	S	A	0.1876
80	S	A	0.4816
81	V	A	-0.0607
82	P	A	-0.4000
83	S	A	-1.1604
84	Q	A	-1.5703
85	K	A	-1.8816
86	T	A	-0.3073
87	Y	A	1.1201
88	P	A	1.3994
89	A	A	1.0002
90	P	A	0.2344
91	I	A	0.7601
92	V	A	2.1916
93	S	A	1.8062
94	V	A	2.1108
95	W	A	0.9481
96	A	A	0.3163
97	S	A	0.3970
98	C	A	1.1488
99	I	A	1.7530
100	L	A	0.8206
101	G	A	-0.3598
102	Q	A	-1.1964
103	P	A	-0.6873
104	S	A	0.0177
105	L	A	0.3306
106	S	A	0.7165
107	P	A	0.7440
108	T	A	0.3093
109	R	A	-0.2013
110	T	A	0.2046
111	P	A	0.1226
112	L	A	0.8634
113	N	A	-0.0157
114	L	A	0.6867
115	T	A	0.3843
116	C	A	0.7738
117	C	A	1.2103
118	F	A	2.0505
119	A	A	0.8083
120	G	A	-0.0129
121	W	A	-0.1011
122	Q	A	-1.1810
123	R	A	-0.5141
124	P	A	-0.4373
125	V	A	0.1541
126	Q	A	-0.2494
127	C	A	0.7829
128	S	A	0.8488
129	C	A	0.9321
130	G	A	0.4867
131	S	A	-0.3680
132	P	A	-0.9919
133	Q	A	-1.9211
134	H	A	-1.7328
135	P	A	-1.7205
136	R	A	-2.3965
137	P	A	-1.1036
138	A	A	-0.8794
139	P	A	0.0282
140	V	A	0.7503
141	F	A	1.2444
142	T	A	0.0000
143	P	A	0.2475
144	W	A	0.1623
145	P	A	-0.6963
146	S	A	-1.3899
147	T	A	-1.5835
148	R	A	-3.3099
149	R	A	-3.4612
150	Q	A	-2.9577
151	H	A	-2.5174
152	M	A	-1.6789
153	M	A	-1.1719
154	E	A	-1.9217
155	V	A	-0.3801
156	V	A	-0.6298
157	K	A	-2.1000
158	H	A	-1.4877
159	C	A	-0.4480
160	P	A	-0.9824
161	H	A	-1.1588
162	L	A	-1.3440
163	E	A	-2.0925
164	C	A	-0.3722
165	R	A	-0.2660
166	C	A	0.4592
167	D	A	-0.3216
168	Y	A	0.7551
169	S	A	-0.0544
170	D	A	-1.0624
171	C	A	0.6538
172	L	A	1.3263
173	D	A	0.3751
174	P	A	-0.3223
175	P	A	-0.5916
176	Q	A	-1.5072
177	H	A	-0.9556
178	L	A	-0.4251
179	I	A	-0.1767
180	Q	A	-0.3156
181	I	A	0.0455
182	T	A	-0.3888