Project name: 5itf:B

Chain sequence(s)	B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8833
• Maximal score value: 2.5987
• Average score: -0.5356
• Total score value: -116.2222

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4854
2	V	B	-0.8981
3	Q	B	-1.6682
4	L	B	0.0000
5	K	B	-2.2946
6	Q	B	0.0000
7	S	B	-0.8747
8	G	B	-1.2341
9	P	B	-0.5550
10	G	B	-0.4516
11	L	B	-0.1434
12	V	B	0.0000
13	Q	B	-1.8241
14	P	B	-1.7097
15	S	B	-1.7483
16	Q	B	-2.2271
17	S	B	-2.0172
18	L	B	0.0000
19	S	B	-0.7445
20	I	B	0.0000
21	T	B	-0.6136
22	C	B	0.0000
23	T	B	-1.1979
24	V	B	0.0000
25	S	B	-1.2768
26	G	B	-1.0173
27	F	B	-0.5484
28	S	B	-0.9484
29	L	B	0.0000
30	T	B	-0.9884
31	N	B	-0.8944
32	Y	B	0.4433
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.4730
40	S	B	-1.0414
41	P	B	-1.1375
42	G	B	-1.6537
43	K	B	-2.0968
44	G	B	-0.7281
45	L	B	0.6401
46	E	B	-0.0850
47	W	B	0.3209
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.5543
53	S	B	-0.6651
54	G	B	-1.2461
55	G	B	-1.5356
56	N	B	-1.9346
57	T	B	-1.5070
58	D	B	-1.5310
59	Y	B	-0.6664
60	N	B	-0.6492
61	T	B	-0.5111
62	P	B	-0.4613
63	F	B	0.0000
64	T	B	-0.5959
65	S	B	-0.6961
66	R	B	-1.2200
67	L	B	0.0000
68	S	B	-1.1179
69	I	B	0.0000
70	N	B	-1.8174
71	K	B	-1.6445
72	D	B	-2.0040
73	N	B	-2.6217
74	S	B	-1.8739
75	K	B	-2.5020
76	S	B	-1.7783
77	Q	B	-1.6821
78	V	B	0.0000
79	F	B	-0.4859
80	F	B	0.0000
81	K	B	-1.5234
82	M	B	0.0000
83	N	B	-2.3321
84	S	B	-1.8483
85	L	B	0.0000
86	Q	B	-2.3414
87	S	B	-1.6156
88	N	B	-2.0927
89	D	B	0.0000
90	T	B	-0.7096
91	A	B	0.0000
92	I	B	0.5546
93	Y	B	0.0000
94	Y	B	0.0574
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.4121
100	T	B	1.2090
101	Y	B	1.8895
102	Y	B	1.7143
103	D	B	0.6723
104	Y	B	0.6075
105	E	B	-0.4085
106	F	B	0.4062
107	A	B	0.6076
108	Y	B	0.4333
109	W	B	0.0723
110	G	B	0.0000
111	Q	B	-1.5296
112	G	B	-0.6664
113	T	B	0.0000
114	L	B	0.1767
115	V	B	0.0000
116	T	B	-0.3847
117	V	B	0.0000
118	S	B	-0.6585
119	A	B	-0.4503
120	A	B	-0.3442
121	S	B	-0.5417
122	T	B	-0.7084
123	K	B	-1.1756
124	G	B	-1.4569
125	P	B	-0.5975
126	S	B	-0.0902
127	V	B	0.0000
128	F	B	0.9105
129	P	B	-0.1228
130	L	B	0.3522
131	A	B	-0.8905
132	P	B	0.0000
133	S	B	-0.8893
134	S	B	-0.4278
138	S	B	-0.6767
139	G	B	-0.8621
140	G	B	-0.9693
141	T	B	-0.6665
142	A	B	0.0000
143	A	B	0.0656
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.6609
148	V	B	0.0000
149	K	B	-0.2305
150	D	B	-0.7270
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.3955
155	P	B	-0.6184
156	V	B	-0.5464
157	T	B	-0.4979
158	V	B	-0.1998
159	S	B	-0.4367
160	W	B	0.0000
161	N	B	-0.6979
162	S	B	-0.6403
163	G	B	-0.4996
164	A	B	-0.2314
165	L	B	0.0004
166	T	B	-0.3011
167	S	B	-0.3222
168	G	B	-0.3527
169	V	B	-0.1000
170	H	B	-0.5185
171	T	B	0.2359
172	F	B	1.2016
173	P	B	0.8710
174	A	B	1.4096
175	V	B	2.5987
176	L	B	2.1510
177	Q	B	0.6907
178	S	B	0.0960
179	S	B	-0.2458
180	G	B	0.1637
181	L	B	0.2566
182	Y	B	0.8087
183	S	B	0.0000
184	L	B	1.0359
185	S	B	0.7596
186	S	B	0.0000
187	V	B	0.3755
188	V	B	0.0000
189	T	B	-0.2262
190	V	B	0.0000
191	P	B	-0.6001
192	S	B	-0.7008
193	S	B	-0.6856
194	S	B	-0.7491
195	L	B	-0.9290
196	G	B	-1.0528
197	T	B	-0.8328
198	Q	B	-1.4107
199	T	B	-1.2108
200	Y	B	0.0000
201	I	B	-1.3408
202	C	B	0.0000
203	N	B	-1.3782
204	V	B	0.0000
205	N	B	-1.7236
206	H	B	0.0000
207	K	B	-2.7686
208	P	B	-1.5800
209	S	B	-1.8189
210	N	B	-2.5036
211	T	B	-1.9534
212	K	B	-2.5539
213	V	B	-1.5876
214	D	B	-2.5215
215	K	B	-1.9238
216	R	B	-2.6157
217	V	B	0.0000
218	E	B	-2.8833
219	P	B	-1.8761
220	K	B	-2.2361