Project name: d73d9557a34f95b

Chain sequence(s)	A: EDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQQLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.7886
• Maximal score value: 1.4409
• Average score: -2.3648
• Total score value: -385.4607

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
436	E	A	-2.8837
437	D	A	-2.8233
438	S	A	-1.8787
439	V	A	-1.4325
440	E	A	-2.2254
441	A	A	-1.6583
442	V	A	-0.9781
443	G	A	0.0000
444	A	A	-0.5707
445	Q	A	-0.5969
446	L	A	0.0000
447	K	A	-1.3663
448	V	A	-0.0079
449	Y	A	-0.8003
450	H	A	-1.7167
451	Q	A	-2.0799
452	Q	A	-2.2179
453	Y	A	-2.3819
454	Q	A	-2.8752
455	D	A	-3.1320
456	K	A	-2.8852
457	S	A	-3.3370
458	R	A	-4.1343
459	E	A	-3.7522
460	Y	A	-3.2273
461	D	A	-3.7790
462	Q	A	-3.4972
463	L	A	0.0000
464	Y	A	-1.7270
465	E	A	-2.9215
466	E	A	-2.5734
467	Y	A	-2.1866
468	T	A	-1.9694
469	R	A	-3.3841
470	T	A	-2.5797
471	S	A	-2.4226
472	Q	A	-3.1936
473	E	A	-3.2472
474	L	A	-2.5994
475	Q	A	-2.6379
476	M	A	-1.5550
477	K	A	-2.3483
478	R	A	-2.9923
479	T	A	-1.7889
480	A	A	-1.3722
481	I	A	-1.8602
482	E	A	-2.6625
483	A	A	-1.8118
484	F	A	-1.0725
485	N	A	-2.1291
486	E	A	-2.6035
487	T	A	-1.4570
488	I	A	0.0000
489	K	A	-2.9323
490	I	A	-1.6217
491	F	A	-2.2473
492	E	A	-3.6210
493	E	A	-3.7566
494	Q	A	-3.1112
495	G	A	-3.7984
496	Q	A	-3.6911
497	T	A	-3.3701
498	Q	A	-3.8160
499	E	A	-4.4613
500	K	A	-3.8963
501	C	A	-2.2626
502	S	A	-2.6151
503	K	A	-3.8557
504	E	A	-3.2979
505	Y	A	-1.6392
506	L	A	-3.0071
507	E	A	-3.8740
508	R	A	-4.4103
509	F	A	-4.2767
510	R	A	-4.7467
511	R	A	-4.7886
512	E	A	-4.4202
513	G	A	-4.3777
514	N	A	-4.0688
515	E	A	-4.5063
516	K	A	-3.9314
517	E	A	-3.3726
518	M	A	-2.5951
519	Q	A	-2.6689
520	R	A	-2.8198
521	I	A	-1.5233
522	L	A	-0.7426
523	L	A	-1.0741
524	N	A	-2.4113
525	S	A	-2.8770
526	E	A	-3.4480
527	R	A	-3.7968
528	L	A	-3.2497
529	K	A	-3.7905
530	S	A	-3.5761
531	R	A	-3.7392
532	I	A	0.0000
533	A	A	-2.6561
534	E	A	-3.6119
535	I	A	-2.4186
536	H	A	-2.5199
537	E	A	-3.2160
538	S	A	-2.1475
539	R	A	-2.3592
540	T	A	-2.3797
541	K	A	-3.1277
542	L	A	-2.6555
543	E	A	-3.2082
544	Q	A	-3.1915
545	Q	A	-2.8280
546	L	A	0.0000
547	R	A	-2.9788
548	A	A	-2.1067
549	Q	A	-2.5915
550	A	A	-2.3501
551	S	A	-2.7335
552	D	A	-3.5422
553	N	A	0.0000
554	R	A	-4.0625
555	E	A	-4.5668
556	I	A	-3.1214
557	D	A	-3.3084
558	K	A	-4.3152
559	R	A	-3.5354
560	M	A	0.0000
561	N	A	-2.6301
562	S	A	-1.8895
563	L	A	-1.6083
564	K	A	-1.3953
565	P	A	-1.0356
566	D	A	-1.7485
567	L	A	-1.4528
568	M	A	-0.9518
569	Q	A	-2.0316
570	L	A	0.0000
571	R	A	-3.1753
572	K	A	-3.0106
573	I	A	-1.3573
574	R	A	-1.7328
575	D	A	-1.7010
576	Q	A	-0.6688
577	Y	A	0.1138
578	L	A	0.3466
579	V	A	1.4409
580	W	A	0.8468
581	L	A	0.0000
582	T	A	-0.6746
583	Q	A	-1.1258
584	K	A	-1.1065
585	G	A	-1.3621
586	A	A	-2.1738
587	R	A	-3.4676
588	Q	A	-3.6115
589	K	A	-3.6385
590	K	A	-3.6399
591	I	A	-2.5670
592	N	A	-2.7066
593	E	A	-3.0897
594	W	A	0.0000
595	L	A	-1.1858
596	G	A	-1.0960
597	I	A	-0.1379
598	K	A	-1.2837