| Chain sequence(s) |
H: QVQLVQSGAEVKKPGSSVKVSCKASHQDSILYGISWVRQAPGQGLEWMGGVIPIFNLAHEADGFQGRVTITADESTSTAYMELSSLRSEQTAVYYCARSSRIYDLNPSLTAYYDMQVWGQGTMVTVS L: SVLTQPPSVSAAPGQKVTISCSRSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAWVFGGGTKLTVLRT |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | Q | H | -1.4872 | |
| 2 | V | H | -1.0430 | |
| 3 | Q | H | -1.6195 | |
| 4 | L | H | 0.0000 | |
| 5 | V | H | -0.0453 | |
| 6 | Q | H | 0.0000 | |
| 7 | S | H | -0.6940 | |
| 8 | G | H | -0.6848 | |
| 9 | A | H | -0.1449 | |
| 10 | E | H | -0.5419 | |
| 11 | V | H | 0.6495 | |
| 12 | K | H | -1.0995 | |
| 13 | K | H | -2.1210 | |
| 14 | P | H | -1.9987 | |
| 15 | G | H | -1.5358 | |
| 16 | S | H | -1.2477 | |
| 17 | S | H | -1.4389 | |
| 18 | V | H | 0.0000 | |
| 19 | K | H | -2.1445 | |
| 20 | V | H | 0.0000 | |
| 21 | S | H | -0.6353 | |
| 22 | C | H | 0.0000 | |
| 23 | K | H | -1.3011 | |
| 24 | A | H | -1.2461 | |
| 25 | S | H | -1.4956 | |
| 26 | H | H | -1.9899 | |
| 27 | Q | H | -1.7890 | |
| 28 | D | H | -1.8117 | |
| 29 | S | H | 0.0000 | |
| 30 | I | H | 0.2151 | |
| 31 | L | H | 1.4088 | |
| 32 | Y | H | 0.8249 | |
| 33 | G | H | 0.0000 | |
| 34 | I | H | 0.0000 | |
| 35 | S | H | 0.0000 | |
| 36 | W | H | 0.0000 | |
| 37 | V | H | 0.0000 | |
| 38 | R | H | 0.0000 | |
| 39 | Q | H | -0.7072 | |
| 40 | A | H | 0.0000 | |
| 41 | P | H | -1.1142 | |
| 42 | G | H | -1.2410 | |
| 43 | Q | H | -1.8184 | |
| 44 | G | H | -1.2735 | |
| 45 | L | H | 0.0000 | |
| 46 | E | H | -0.7928 | |
| 47 | W | H | 0.0000 | |
| 48 | M | H | 0.0000 | |
| 49 | G | H | 0.0000 | |
| 50 | G | H | 0.0000 | |
| 51 | V | H | 0.0000 | |
| 52 | I | H | 0.0000 | |
| 52A | P | H | 0.0000 | |
| 53 | I | H | 1.0607 | |
| 54 | F | H | 1.1246 | |
| 55 | N | H | -0.3069 | |
| 56 | L | H | 0.5526 | |
| 57 | A | H | -0.1109 | |
| 58 | H | H | -0.8199 | |
| 59 | E | H | -1.8531 | |
| 60 | A | H | -1.7878 | |
| 61 | D | H | -2.5983 | |
| 62 | G | H | -1.9676 | |
| 63 | F | H | 0.0000 | |
| 64 | Q | H | -2.5847 | |
| 65 | G | H | -1.7701 | |
| 66 | R | H | -1.4815 | |
| 67 | V | H | 0.0000 | |
| 68 | T | H | -0.9598 | |
| 69 | I | H | -0.4533 | |
| 70 | T | H | -0.4607 | |
| 71 | A | H | -0.7888 | |
| 72 | D | H | -1.6622 | |
| 73 | E | H | -1.7275 | |
| 74 | S | H | -1.1268 | |
| 75 | T | H | -1.2597 | |
| 76 | S | H | -1.5547 | |
| 77 | T | H | 0.0000 | |
| 78 | A | H | 0.0000 | |
| 79 | Y | H | -0.6001 | |
| 80 | M | H | 0.0000 | |
| 81 | E | H | -1.6145 | |
| 82 | L | H | 0.0000 | |
| 82A | S | H | -1.2127 | |
| 82B | S | H | -1.1772 | |
| 82C | L | H | 0.0000 | |
| 83 | R | H | -2.7948 | |
| 84 | S | H | -2.2684 | |
| 85 | E | H | -2.4949 | |
| 86 | Q | H | 0.0000 | |
| 87 | T | H | -0.7198 | |
| 88 | A | H | 0.0000 | |
| 89 | V | H | 0.2962 | |
| 90 | Y | H | 0.0000 | |
| 91 | Y | H | 0.0000 | |
| 92 | C | H | 0.0000 | |
| 93 | A | H | 0.0000 | |
| 94 | R | H | 0.0000 | |
| 95 | S | H | 0.0000 | |
| 96 | S | H | 0.6022 | |
| 97 | R | H | 0.0000 | |
| 98 | I | H | 2.0923 | |
| 99 | Y | H | 1.5839 | |
| 100 | D | H | -0.7086 | |
| 100A | L | H | -0.1980 | |
| 100B | N | H | -1.1562 | |
| 100C | P | H | -0.8835 | |
| 100D | S | H | -0.6804 | |
| 100E | L | H | -0.1855 | |
| 100F | T | H | 0.0000 | |
| 100G | A | H | 0.0000 | |
| 100H | Y | H | 0.0000 | |
| 100I | Y | H | 0.2513 | |
| 100J | D | H | 0.0000 | |
| 100K | M | H | 0.0000 | |
| 101 | Q | H | -0.6365 | |
| 102 | V | H | -0.4249 | |
| 103 | W | H | -0.3615 | |
| 104 | G | H | 0.0000 | |
| 105 | Q | H | -1.0431 | |
| 106 | G | H | -0.3997 | |
| 107 | T | H | 0.0000 | |
| 108 | M | H | 0.3261 | |
| 109 | V | H | 0.0000 | |
| 110 | T | H | -0.3219 | |
| 111 | V | H | 0.0000 | |
| 112 | S | H | -1.0550 | |
| 2 | S | L | 0.2128 | |
| 3 | V | L | 1.4559 | |
| 4 | L | L | 0.0000 | |
| 5 | T | L | 0.0010 | |
| 6 | Q | L | -0.4246 | |
| 7 | P | L | -0.5400 | |
| 8 | P | L | -0.7538 | |
| 10 | S | L | -0.7611 | |
| 11 | V | L | -0.2920 | |
| 12 | S | L | -0.5145 | |
| 13 | A | L | 0.0000 | |
| 14 | A | L | -1.0066 | |
| 15 | P | L | -1.4927 | |
| 16 | G | L | -1.7564 | |
| 17 | Q | L | -2.3026 | |
| 18 | K | L | -2.4942 | |
| 19 | V | L | 0.0000 | |
| 20 | T | L | -0.5026 | |
| 21 | I | L | 0.0000 | |
| 22 | S | L | -0.2853 | |
| 23 | C | L | 0.0000 | |
| 24 | S | L | -0.2521 | |
| 25 | R | L | -0.2776 | |
| 26 | S | L | -0.7348 | |
| 27 | S | L | -0.9575 | |
| 28 | S | L | -0.6765 | |
| 29 | N | L | 0.0000 | |
| 30 | I | L | 0.0000 | |
| 30A | G | L | -1.3512 | |
| 30B | N | L | -1.4323 | |
| 31 | N | L | 0.0000 | |
| 32 | Y | L | 0.0121 | |
| 33 | V | L | 0.0000 | |
| 34 | S | L | 0.0000 | |
| 35 | W | L | 0.0000 | |
| 36 | Y | L | 0.0000 | |
| 37 | Q | L | 0.0000 | |
| 38 | Q | L | 0.0000 | |
| 39 | L | L | -0.4010 | |
| 40 | P | L | -0.5458 | |
| 41 | G | L | -0.4452 | |
| 42 | T | L | -0.5186 | |
| 43 | A | L | -0.4653 | |
| 44 | P | L | 0.0000 | |
| 45 | K | L | -0.8865 | |
| 46 | L | L | 0.0000 | |
| 47 | L | L | 0.0000 | |
| 48 | I | L | 0.0000 | |
| 49 | Y | L | -0.5163 | |
| 50 | D | L | -1.0879 | |
| 51 | N | L | -1.5048 | |
| 52 | N | L | -2.4767 | |
| 53 | K | L | -2.6695 | |
| 54 | R | L | -1.7404 | |
| 55 | P | L | 0.0000 | |
| 56 | S | L | -0.5485 | |
| 57 | G | L | -0.7286 | |
| 58 | I | L | -0.8529 | |
| 59 | P | L | -1.2484 | |
| 60 | D | L | -2.3116 | |
| 61 | R | L | -1.6382 | |
| 62 | F | L | 0.0000 | |
| 63 | S | L | -1.3950 | |
| 64 | G | L | -1.4107 | |
| 65 | S | L | -1.5210 | |
| 66 | K | L | -1.6253 | |
| 67 | S | L | -1.1189 | |
| 68 | G | L | -1.2057 | |
| 69 | T | L | -1.0757 | |
| 70 | S | L | -0.8938 | |
| 71 | A | L | 0.0000 | |
| 72 | T | L | -0.7099 | |
| 73 | L | L | 0.0000 | |
| 74 | G | L | -0.6098 | |
| 75 | I | L | 0.0000 | |
| 76 | T | L | -1.8170 | |
| 77 | G | L | -1.7212 | |
| 78 | L | L | 0.0000 | |
| 79 | Q | L | -1.9237 | |
| 80 | T | L | -1.4004 | |
| 81 | G | L | -1.3262 | |
| 82 | D | L | 0.0000 | |
| 83 | E | L | -2.1929 | |
| 84 | A | L | 0.0000 | |
| 85 | D | L | -1.1268 | |
| 86 | Y | L | 0.0000 | |
| 87 | Y | L | 0.0000 | |
| 88 | C | L | 0.0000 | |
| 89 | G | L | 0.0000 | |
| 90 | T | L | 0.0000 | |
| 91 | W | L | 0.0000 | |
| 92 | D | L | 0.0000 | |
| 93 | S | L | -0.3430 | |
| 94 | S | L | 0.0865 | |
| 95 | L | L | 0.1527 | |
| 95A | S | L | -0.2204 | |
| 95B | A | L | 0.0000 | |
| 96 | W | L | 0.0000 | |
| 97 | V | L | 0.0000 | |
| 98 | F | L | 0.0000 | |
| 99 | G | L | 0.0000 | |
| 100 | G | L | -0.6499 | |
| 101 | G | L | -0.9022 | |
| 102 | T | L | 0.0000 | |
| 103 | K | L | -1.6799 | |
| 104 | L | L | 0.0000 | |
| 105 | T | L | -0.7679 | |
| 106 | V | L | -0.8047 | |
| 107 | L | L | -0.0479 | |
| 108 | R | L | -1.3873 | |
| 109 | T | L | -0.7770 |