Project name: 5xhf:A
Status: done
submitted: 2019-03-21 14:58:06, status changed: 2019-03-21 15:08:21
Settings
|
Chain sequence(s)
|
A: DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6832
-
Maximal score value
-
2.4985
-
Average score
-
-0.8621
-
Total score value
-
-182.7604
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-2.2650 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
Q |
A |
-1.9951 |
|
| 4 |
M |
A |
0.0000 |
|
| 5 |
T |
A |
-1.1909 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
-0.8007 |
|
| 8 |
P |
A |
-0.6253 |
|
| 9 |
S |
A |
-0.8613 |
|
| 10 |
S |
A |
-0.6848 |
|
| 11 |
L |
A |
-0.5087 |
|
| 12 |
S |
A |
-0.7687 |
|
| 13 |
A |
A |
0.0000 |
|
| 14 |
S |
A |
-0.7760 |
|
| 15 |
V |
A |
0.2972 |
|
| 16 |
G |
A |
-0.5406 |
|
| 17 |
D |
A |
-1.7009 |
|
| 18 |
R |
A |
-2.2322 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
T |
A |
-0.6492 |
|
| 21 |
I |
A |
0.0000 |
|
| 22 |
T |
A |
-0.6512 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.5703 |
|
| 25 |
A |
A |
-2.1450 |
|
| 26 |
S |
A |
-2.0305 |
|
| 27 |
Q |
A |
-2.6008 |
|
| 28 |
D |
A |
-2.4331 |
|
| 29 |
V |
A |
0.0000 |
|
| 30 |
N |
A |
-1.7487 |
|
| 31 |
T |
A |
-1.0030 |
|
| 32 |
A |
A |
-0.5251 |
|
| 33 |
V |
A |
0.0000 |
|
| 34 |
A |
A |
0.6728 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.1308 |
|
| 37 |
Q |
A |
-0.9576 |
|
| 38 |
Q |
A |
-1.7081 |
|
| 39 |
K |
A |
-2.0854 |
|
| 40 |
P |
A |
-1.6692 |
|
| 41 |
G |
A |
-1.5742 |
|
| 42 |
K |
A |
-2.4586 |
|
| 43 |
A |
A |
-1.6237 |
|
| 44 |
P |
A |
-1.6305 |
|
| 45 |
K |
A |
-1.9815 |
|
| 46 |
L |
A |
-0.2188 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
Y |
A |
1.6648 |
|
| 50 |
S |
A |
0.5045 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
0.7407 |
|
| 53 |
F |
A |
2.4985 |
|
| 54 |
L |
A |
1.9016 |
|
| 55 |
Y |
A |
1.4771 |
|
| 56 |
S |
A |
0.2930 |
|
| 57 |
G |
A |
-0.3087 |
|
| 58 |
V |
A |
0.0000 |
|
| 59 |
P |
A |
-0.2787 |
|
| 60 |
S |
A |
-0.3418 |
|
| 61 |
R |
A |
-0.7059 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
0.2938 |
|
| 64 |
G |
A |
0.0239 |
|
| 65 |
S |
A |
-0.8464 |
|
| 66 |
R |
A |
-2.1900 |
|
| 67 |
S |
A |
-1.5640 |
|
| 68 |
G |
A |
-1.8606 |
|
| 69 |
T |
A |
-2.1087 |
|
| 70 |
D |
A |
-2.0258 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.8703 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
T |
A |
-0.6058 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
S |
A |
-1.2796 |
|
| 77 |
S |
A |
-0.9920 |
|
| 78 |
L |
A |
0.0000 |
|
| 79 |
Q |
A |
-0.8266 |
|
| 80 |
P |
A |
-1.3890 |
|
| 81 |
E |
A |
-1.9739 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
F |
A |
-1.3868 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
T |
A |
-0.9148 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
-0.0276 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.2815 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
H |
A |
-0.4990 |
|
| 92 |
Y |
A |
0.1602 |
|
| 93 |
T |
A |
-0.3554 |
|
| 94 |
T |
A |
-0.4825 |
|
| 95 |
P |
A |
-0.4907 |
|
| 96 |
P |
A |
-0.4019 |
|
| 97 |
T |
A |
-0.1766 |
|
| 98 |
F |
A |
0.8500 |
|
| 99 |
G |
A |
-0.3727 |
|
| 100 |
Q |
A |
-1.1675 |
|
| 101 |
G |
A |
0.0000 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-1.3593 |
|
| 104 |
V |
A |
0.0000 |
|
| 105 |
E |
A |
-1.3994 |
|
| 106 |
I |
A |
0.0000 |
|
| 107 |
K |
A |
-1.7123 |
|
| 108 |
R |
A |
-0.9943 |
|
| 109 |
T |
A |
-0.2326 |
|
| 110 |
V |
A |
0.1083 |
|
| 111 |
A |
A |
-0.1190 |
|
| 112 |
A |
A |
-0.2905 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1858 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.2618 |
|
| 117 |
I |
A |
1.1387 |
|
| 118 |
F |
A |
1.2700 |
|
| 119 |
P |
A |
-0.1036 |
|
| 120 |
P |
A |
-0.9298 |
|
| 121 |
S |
A |
-2.0467 |
|
| 122 |
D |
A |
-3.4405 |
|
| 123 |
E |
A |
-3.6832 |
|
| 124 |
Q |
A |
-3.2085 |
|
| 125 |
L |
A |
-2.8572 |
|
| 126 |
K |
A |
-3.2325 |
|
| 127 |
S |
A |
-2.1173 |
|
| 128 |
G |
A |
-1.7179 |
|
| 129 |
T |
A |
-1.6765 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
-0.1453 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.5808 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.6388 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.8268 |
|
| 138 |
N |
A |
-1.8485 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
0.0000 |
|
| 141 |
P |
A |
-1.9147 |
|
| 142 |
R |
A |
-3.2076 |
|
| 143 |
E |
A |
-3.2604 |
|
| 144 |
A |
A |
-2.3760 |
|
| 145 |
K |
A |
-2.3049 |
|
| 146 |
V |
A |
-1.2225 |
|
| 147 |
Q |
A |
-0.6052 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.3392 |
|
| 150 |
V |
A |
-0.6822 |
|
| 151 |
D |
A |
-1.5841 |
|
| 152 |
N |
A |
-1.4017 |
|
| 153 |
A |
A |
-0.0583 |
|
| 154 |
L |
A |
0.9314 |
|
| 156 |
S |
A |
-0.5980 |
|
| 157 |
G |
A |
-1.4484 |
|
| 158 |
N |
A |
-1.8279 |
|
| 159 |
S |
A |
-1.8356 |
|
| 160 |
Q |
A |
-2.4991 |
|
| 161 |
E |
A |
-2.3822 |
|
| 162 |
S |
A |
-1.2305 |
|
| 163 |
V |
A |
-0.8920 |
|
| 164 |
T |
A |
-1.2551 |
|
| 165 |
E |
A |
-2.3597 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.7910 |
|
| 168 |
S |
A |
-2.4218 |
|
| 169 |
K |
A |
-2.6194 |
|
| 170 |
D |
A |
-2.2679 |
|
| 171 |
S |
A |
-2.3093 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-1.2467 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4935 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.7646 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.5445 |
|
| 181 |
L |
A |
-0.8773 |
|
| 182 |
S |
A |
-1.5919 |
|
| 183 |
K |
A |
-2.6738 |
|
| 184 |
A |
A |
-1.9641 |
|
| 185 |
D |
A |
-2.9472 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.5414 |
|
| 188 |
K |
A |
-3.6032 |
|
| 189 |
H |
A |
-3.0145 |
|
| 190 |
K |
A |
-3.2743 |
|
| 191 |
V |
A |
-1.7185 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.6295 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.1900 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.6309 |
|
| 200 |
G |
A |
-0.4538 |
|
| 201 |
L |
A |
-0.2727 |
|
| 202 |
S |
A |
-0.4535 |
|
| 203 |
S |
A |
-0.4192 |
|
| 204 |
P |
A |
-0.4962 |
|
| 205 |
V |
A |
0.0462 |
|
| 206 |
T |
A |
-0.3041 |
|
| 207 |
K |
A |
-0.3217 |
|
| 208 |
S |
A |
-0.3508 |
|
| 209 |
F |
A |
-0.9102 |
|
| 210 |
N |
A |
-2.0650 |
|
| 211 |
R |
A |
-2.4782 |
|
| 212 |
G |
A |
-2.0204 |
|
| 213 |
E |
A |
-2.5333 |
|