Project name: 5wt9:H

Chain sequence(s)	H: QVQLVESGGGVVQPGRSLRLDCKASGITFSNSGMHWVRQAPGKGLEWVAVIWYDGSKRYYADSVKGRFTISRDNSKNTLFLQMNSLRAEDTAVYYCATNDDYWGQGTLVTVSSASTKGPSVFPLAPCSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0741
• Maximal score value: 2.4372
• Average score: -0.6642
• Total score value: -138.1576

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.3167
2	V	H	-0.5099
3	Q	H	-1.3064
4	L	H	0.0000
5	V	H	-0.3204
6	E	H	0.0000
7	S	H	-0.6508
8	G	H	-0.8509
9	G	H	-0.4159
10	G	H	0.1400
11	V	H	0.4579
12	V	H	0.0000
13	Q	H	-1.4006
14	P	H	-1.8751
15	G	H	-1.9831
16	R	H	-2.6246
17	S	H	-2.0159
18	L	H	-1.3941
19	R	H	-2.0854
20	L	H	0.0000
21	D	H	-1.1337
22	C	H	0.0000
23	K	H	-1.6313
24	A	H	0.0000
25	S	H	-0.9888
26	G	H	-0.7551
27	I	H	-0.3486
28	T	H	-0.5786
29	F	H	0.0000
30	S	H	-1.3469
31	N	H	-1.4800
32	S	H	-1.4397
33	G	H	-1.1176
34	M	H	0.0000
35	H	H	-0.3450
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.4751
40	A	H	-1.0948
41	P	H	-0.9027
42	G	H	-1.4446
43	K	H	-2.0827
44	G	H	-0.9524
45	L	H	0.5769
46	E	H	-0.1977
47	W	H	0.2536
48	V	H	0.0000
49	A	H	0.0000
50	V	H	0.0000
51	I	H	0.0000
52	W	H	-0.7857
53	Y	H	-0.7549
54	D	H	-1.9861
55	G	H	-1.4152
56	S	H	-1.3420
57	K	H	-1.5093
58	R	H	-1.0032
59	Y	H	0.0107
60	Y	H	-0.5676
61	A	H	-1.1234
62	D	H	-2.2572
63	S	H	-1.7643
64	V	H	0.0000
65	K	H	-2.4513
66	G	H	-1.8031
67	R	H	-1.4172
68	F	H	0.0000
69	T	H	-0.8275
70	I	H	0.0000
71	S	H	-0.4043
72	R	H	-1.0385
73	D	H	-1.6563
74	N	H	-2.0416
75	S	H	-1.6659
76	K	H	-2.5756
77	N	H	-1.9963
78	T	H	-1.5892
79	L	H	0.0000
80	F	H	-0.6330
81	L	H	0.0000
82	Q	H	-1.1429
83	M	H	0.0000
84	N	H	-1.9031
85	S	H	-1.6901
86	L	H	0.0000
87	R	H	-2.5397
88	A	H	-1.6854
89	E	H	-2.2678
90	D	H	0.0000
91	T	H	-0.7074
92	A	H	0.0000
93	V	H	0.3293
94	Y	H	0.0000
95	Y	H	0.2884
96	C	H	0.0000
97	A	H	0.0000
98	T	H	0.0000
99	N	H	-2.5914
100	D	H	-3.0741
101	D	H	-2.6525
102	Y	H	-0.9380
103	W	H	-0.3435
104	G	H	-0.5184
105	Q	H	-0.9968
106	G	H	-0.2951
107	T	H	-0.0331
108	L	H	0.4789
109	V	H	0.0000
110	T	H	0.0000
111	V	H	0.0000
112	S	H	-0.6754
113	S	H	-0.4038
114	A	H	-0.3552
115	S	H	-0.4673
116	T	H	-0.6423
117	K	H	-1.2860
118	G	H	-1.4402
119	P	H	-0.5330
120	S	H	-0.0378
121	V	H	0.0000
122	F	H	1.0712
123	P	H	0.1182
124	L	H	0.4706
125	A	H	-0.6885
126	P	H	0.0000
127	C	H	0.2858
134	S	H	-0.3639
135	T	H	-0.2261
136	A	H	0.0000
137	A	H	0.2412
138	L	H	0.0000
139	G	H	0.0000
140	C	H	0.0000
141	L	H	0.7764
142	V	H	0.0000
143	K	H	-0.1769
144	D	H	-0.5983
145	Y	H	0.0000
146	F	H	0.0000
147	P	H	0.0000
148	E	H	-0.3406
149	P	H	-0.8009
150	V	H	-0.5444
151	T	H	-0.5523
152	V	H	-0.1574
153	S	H	-0.4577
154	W	H	0.0000
155	N	H	-0.9884
156	S	H	-0.7462
157	G	H	-0.5489
158	A	H	-0.2496
159	L	H	-0.1323
160	T	H	-0.3681
161	S	H	-0.4374
162	G	H	-0.5656
163	V	H	-0.1870
164	H	H	-0.6195
165	T	H	0.0743
166	F	H	0.8691
167	P	H	0.5787
168	A	H	1.1956
169	V	H	2.4372
170	L	H	2.1738
171	Q	H	0.7955
172	S	H	0.1675
173	S	H	-0.1457
174	G	H	0.2592
175	L	H	0.2993
176	Y	H	0.7545
177	S	H	0.0000
178	L	H	0.0000
179	S	H	0.6238
180	S	H	0.0000
181	V	H	0.3064
182	V	H	0.0000
183	T	H	-0.2635
184	V	H	0.0000
185	P	H	-0.5048
186	S	H	-0.2533
187	S	H	-0.5478
188	S	H	-0.6435
189	L	H	-0.6840
190	G	H	-1.0033
191	T	H	-0.8847
192	K	H	-1.6539
193	T	H	-1.4309
194	Y	H	0.0000
195	T	H	-1.8894
196	C	H	0.0000
197	N	H	-1.6417
198	V	H	0.0000
199	D	H	-1.7997
200	H	H	0.0000
201	K	H	-2.7547
202	P	H	-1.7490
203	S	H	-1.8919
204	N	H	-2.5600
205	T	H	-2.0653
206	K	H	-2.6273
207	V	H	-1.8264
208	D	H	-2.8235
209	K	H	-2.3124
210	R	H	-2.8952
211	V	H	0.0000
212	E	H	-2.8842
213	S	H	-1.7135
214	K	H	-2.0979